882 related articles for article (PubMed ID: 1304349)
1. The refined 1.9-A X-ray crystal structure of D-Phe-Pro-Arg chloromethylketone-inhibited human alpha-thrombin: structure analysis, overall structure, electrostatic properties, detailed active-site geometry, and structure-function relationships.
Bode W; Turk D; Karshikov A
Protein Sci; 1992 Apr; 1(4):426-71. PubMed ID: 1304349
[TBL] [Abstract][Full Text] [Related]
2. The isomorphous structures of prethrombin2, hirugen-, and PPACK-thrombin: changes accompanying activation and exosite binding to thrombin.
Vijayalakshmi J; Padmanabhan KP; Mann KG; Tulinsky A
Protein Sci; 1994 Dec; 3(12):2254-71. PubMed ID: 7756983
[TBL] [Abstract][Full Text] [Related]
3. The refined 1.9 A crystal structure of human alpha-thrombin: interaction with D-Phe-Pro-Arg chloromethylketone and significance of the Tyr-Pro-Pro-Trp insertion segment.
Bode W; Mayr I; Baumann U; Huber R; Stone SR; Hofsteenge J
EMBO J; 1989 Nov; 8(11):3467-75. PubMed ID: 2583108
[TBL] [Abstract][Full Text] [Related]
4. New insights into the regulation of the blood clotting cascade derived from the X-ray crystal structure of bovine meizothrombin des F1 in complex with PPACK.
Martin PD; Malkowski MG; Box J; Esmon CT; Edwards BF
Structure; 1997 Dec; 5(12):1681-93. PubMed ID: 9438869
[TBL] [Abstract][Full Text] [Related]
5. The 2.2 A crystal structure of human chymase in complex with succinyl-Ala-Ala-Pro-Phe-chloromethylketone: structural explanation for its dipeptidyl carboxypeptidase specificity.
Pereira PJ; Wang ZM; Rubin H; Huber R; Bode W; Schechter NM; Strobl S
J Mol Biol; 1999 Feb; 286(1):163-73. PubMed ID: 9931257
[TBL] [Abstract][Full Text] [Related]
6. Bovine chymotrypsinogen A X-ray crystal structure analysis and refinement of a new crystal form at 1.8 A resolution.
Wang D; Bode W; Huber R
J Mol Biol; 1985 Oct; 185(3):595-624. PubMed ID: 4057257
[TBL] [Abstract][Full Text] [Related]
7. Refined structure of the hirudin-thrombin complex.
Rydel TJ; Tulinsky A; Bode W; Huber R
J Mol Biol; 1991 Sep; 221(2):583-601. PubMed ID: 1920434
[TBL] [Abstract][Full Text] [Related]
8. Structures of the noncovalent complexes of human and bovine prothrombin fragment 2 with human PPACK-thrombin.
Arni RK; Padmanabhan K; Padmanabhan KP; Wu TP; Tulinsky A
Biochemistry; 1993 May; 32(18):4727-37. PubMed ID: 8387813
[TBL] [Abstract][Full Text] [Related]
9. Comparison of the structures of the cyclotheonamide A complexes of human alpha-thrombin and bovine beta-trypsin.
Ganesh V; Lee AY; Clardy J; Tulinsky A
Protein Sci; 1996 May; 5(5):825-35. PubMed ID: 8732754
[TBL] [Abstract][Full Text] [Related]
10. Role of thrombin exosites in inhibition by heparin cofactor II.
Rogers SJ; Pratt CW; Whinna HC; Church FC
J Biol Chem; 1992 Feb; 267(6):3613-7. PubMed ID: 1740413
[TBL] [Abstract][Full Text] [Related]
11. The high-resolution X-ray crystal structure of the complex formed between subtilisin Carlsberg and eglin c, an elastase inhibitor from the leech Hirudo medicinalis. Structural analysis, subtilisin structure and interface geometry.
Bode W; Papamokos E; Musil D
Eur J Biochem; 1987 Aug; 166(3):673-92. PubMed ID: 3301348
[TBL] [Abstract][Full Text] [Related]
12. Geometry of binding of the benzamidine- and arginine-based inhibitors N alpha-(2-naphthyl-sulphonyl-glycyl)-DL-p-amidinophenylalanyl-pipe ridine (NAPAP) and (2R,4R)-4-methyl-1-[N alpha-(3-methyl-1,2,3,4-tetrahydro-8- quinolinesulphonyl)-L-arginyl]-2-piperidine carboxylic acid (MQPA) to human alpha-thrombin. X-ray crystallographic determination of the NAPAP-trypsin complex and modeling of NAPAP-thrombin and MQPA-thrombin.
Bode W; Turk D; Stürzebecher J
Eur J Biochem; 1990 Oct; 193(1):175-82. PubMed ID: 2226434
[TBL] [Abstract][Full Text] [Related]
13. Structure of the non-covalent complex of prothrombin kringle 2 with PPACK-thrombin.
Arni RK; Padmanabhan K; Padmanabhan KP; Wu TP; Tulinsky A
Chem Phys Lipids; 1994 Jan; 67-68():59-66. PubMed ID: 8187245
[TBL] [Abstract][Full Text] [Related]
14. Structure of the hirugen and hirulog 1 complexes of alpha-thrombin.
Skrzypczak-Jankun E; Carperos VE; Ravichandran KG; Tulinsky A; Westbrook M; Maraganore JM
J Mol Biol; 1991 Oct; 221(4):1379-93. PubMed ID: 1942057
[TBL] [Abstract][Full Text] [Related]
15. Crystal structure of two new bifunctional nonsubstrate type thrombin inhibitors complexed with human alpha-thrombin.
Féthière J; Tsuda Y; Coulombe R; Konishi Y; Cygler M
Protein Sci; 1996 Jun; 5(6):1174-83. PubMed ID: 8762149
[TBL] [Abstract][Full Text] [Related]
16. The co-crystal structure of unliganded bovine alpha-thrombin and prethrombin-2: movement of the Tyr-Pro-Pro-Trp segment and active site residues upon ligand binding.
Malkowski MG; Martin PD; Guzik JC; Edwards BF
Protein Sci; 1997 Jul; 6(7):1438-48. PubMed ID: 9232645
[TBL] [Abstract][Full Text] [Related]
17. Bifunctional peptide boronate inhibitors of thrombin: crystallographic analysis of inhibition enhanced by linkage to an exosite 1 binding peptide.
Skordalakes E; Elgendy S; Goodwin CA; Green D; Scully MF; Kakkar VV; Freyssinet JM; Dodson G; Deadman JJ
Biochemistry; 1998 Oct; 37(41):14420-7. PubMed ID: 9772168
[TBL] [Abstract][Full Text] [Related]
18. Structural basis of thrombin-mediated factor V activation: the Glu666-Glu672 sequence is critical for processing at the heavy chain-B domain junction.
Corral-Rodríguez MÁ; Bock PE; Hernández-Carvajal E; Gutiérrez-Gallego R; Fuentes-Prior P
Blood; 2011 Jun; 117(26):7164-73. PubMed ID: 21555742
[TBL] [Abstract][Full Text] [Related]
19. Structure of the thrombin complex with triabin, a lipocalin-like exosite-binding inhibitor derived from a triatomine bug.
Fuentes-Prior P; Noeske-Jungblut C; Donner P; Schleuning WD; Huber R; Bode W
Proc Natl Acad Sci U S A; 1997 Oct; 94(22):11845-50. PubMed ID: 9342325
[TBL] [Abstract][Full Text] [Related]
20. X-ray analyses of aspartic proteinases. The three-dimensional structure at 2.1 A resolution of endothiapepsin.
Blundell TL; Jenkins JA; Sewell BT; Pearl LH; Cooper JB; Tickle IJ; Veerapandian B; Wood SP
J Mol Biol; 1990 Feb; 211(4):919-41. PubMed ID: 2179568
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
