BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

111 related articles for article (PubMed ID: 1306804)

  • 21. Cynomolgus monkey CYP2D44 newly identified in liver, metabolizes bufuralol, and dextromethorphan.
    Uno Y; Uehara S; Kohara S; Murayama N; Yamazaki H
    Drug Metab Dispos; 2010 Sep; 38(9):1486-92. PubMed ID: 20501912
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Effect of sodium ozagrel on the activity of rat CYP2D6.
    Wu H; Yu W; Huang L; Wang J; Tang X; Yang W; Liu Y; Yu H; Zhu D
    Eur J Pharmacol; 2007 Nov; 573(1-3):55-9. PubMed ID: 17651725
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Effects of freezing, thawing, and storing human liver microsomes on cytochrome P450 activity.
    Pearce RE; McIntyre CJ; Madan A; Sanzgiri U; Draper AJ; Bullock PL; Cook DC; Burton LA; Latham J; Nevins C; Parkinson A
    Arch Biochem Biophys; 1996 Jul; 331(2):145-69. PubMed ID: 8660694
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Assessment of individual CYP2D6 activity in extensive metabolizers with renal failure: comparison of sparteine and dextromethorphan.
    Kévorkian JP; Michel C; Hofmann U; Jacqz-Aigrain E; Kroemer HK; Peraldi MN; Eichelbaum M; Jaillon P; Funck-Brentano C
    Clin Pharmacol Ther; 1996 May; 59(5):583-92. PubMed ID: 8646830
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Involvement of human cytochrome P450 2D6 in the bioactivation of acetaminophen.
    Dong H; Haining RL; Thummel KE; Rettie AE; Nelson SD
    Drug Metab Dispos; 2000 Dec; 28(12):1397-400. PubMed ID: 11095574
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Metabolism of the antimammary cancer antiestrogenic agent tamoxifen. I. Cytochrome P-450-catalyzed N-demethylation and 4-hydroxylation.
    Mani C; Gelboin HV; Park SS; Pearce R; Parkinson A; Kupfer D
    Drug Metab Dispos; 1993; 21(4):645-56. PubMed ID: 8104124
    [TBL] [Abstract][Full Text] [Related]  

  • 27. The antipsychotic clozapine is metabolized by the polymorphic human microsomal and recombinant cytochrome P450 2D6.
    Fischer V; Vogels B; Maurer G; Tynes RE
    J Pharmacol Exp Ther; 1992 Mar; 260(3):1355-60. PubMed ID: 1545398
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Human hepatic cytochrome P450 2D6-like activity in nonhuman primates: catalytic characterization in vitro.
    Wu D; Otton SV; Morrow P; Inaba T; Kalow W; Sellers EM
    J Pharmacol Exp Ther; 1993 Aug; 266(2):715-9. PubMed ID: 8355202
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Potent inhibition of cytochrome P-450 2D6-mediated dextromethorphan O-demethylation by terbinafine.
    Abdel-Rahman SM; Marcucci K; Boge T; Gotschall RR; Kearns GL; Leeder JS
    Drug Metab Dispos; 1999 Jul; 27(7):770-5. PubMed ID: 10383919
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Influence of N-substitution of 7-methoxy-4-(aminomethyl)-coumarin on cytochrome P450 metabolism and selectivity.
    Venhorst J; Onderwater RC; Meerman JH; Commandeur JN; Vermeulen NP
    Drug Metab Dispos; 2000 Dec; 28(12):1524-32. PubMed ID: 11095593
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Effect of black seed on dextromethorphan O- and N-demethylation in human liver microsomes and healthy human subjects.
    Al-Jenoobi FI; Al-Thukair AA; Abbas FA; Ansari MJ; Alkharfy KM; Al-Mohizea AM; Al-Suwayeh SA; Jamil S
    Drug Metab Lett; 2010 Jan; 4(1):51-5. PubMed ID: 20201775
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Polymorphism of dextromethorphan metabolism: relationships between phenotype, genotype and response to the administration of encainide in humans.
    Funck-Brentano C; Thomas G; Jacqz-Aigrain E; Poirier JM; Simon T; Béréziat G; Jaillon P
    J Pharmacol Exp Ther; 1992 Nov; 263(2):780-6. PubMed ID: 1432700
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Characterization of the selectivity and mechanism of cytochrome P450 inhibition by dimethyl-4,4'-dimethoxy-5,6,5',6'-dimethylenedioxybiphenyl-2,2'-dicarboxylate.
    Kim JY; Baek M; Lee S; Kim SO; Dong MS; Kim BR; Kim DH
    Drug Metab Dispos; 2001 Dec; 29(12):1555-60. PubMed ID: 11717174
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Dextromethorphan metabolism in Jordanians: dissociation of dextromethorphan O-demethylation from debrisoquine 4-hydroxylation.
    Irshaid YM; al-Hadidi HF; Latif A; Awwadi F; al-Zoubi M; Rawashdeh NM
    Eur J Drug Metab Pharmacokinet; 1996; 21(4):301-7. PubMed ID: 9074894
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Pharmacokinetics of dextromethorphan and metabolites in humans: influence of the CYP2D6 phenotype and quinidine inhibition.
    Schadel M; Wu D; Otton SV; Kalow W; Sellers EM
    J Clin Psychopharmacol; 1995 Aug; 15(4):263-9. PubMed ID: 7593709
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Enzymes in addition to CYP3A4 and 3A5 mediate N-demethylation of dextromethorphan in human liver microsomes.
    Wang Y; Unadkat JD
    Biopharm Drug Dispos; 1999 Oct; 20(7):341-6. PubMed ID: 10760842
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Evaluation of dextromethorphan metabolism using hepatocytes from CYP2D6 poor and extensive metabolizers.
    Takashima T; Murase S; Iwasaki K; Shimada K
    Drug Metab Pharmacokinet; 2005 Jun; 20(3):177-82. PubMed ID: 15988119
    [TBL] [Abstract][Full Text] [Related]  

  • 38. A validated SIM GC/MS method for the simultaneous determination of dextromethorphan and its metabolites dextrorphan, 3-methoxymorphinan and 3-hydroxymorphinan in biological matrices and its application to in vitro CYP2D6 and CYP3A4 inhibition study.
    Spanakis M; Vizirianakis IS; Mironidou-Tzouveleki M; Niopas I
    Biomed Chromatogr; 2009 Nov; 23(11):1131-7. PubMed ID: 19444798
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Dextromethorphan O-demethylation in liver microsomes as a prototype reaction to monitor cytochrome P-450 db1 activity.
    Dayer P; Leemann T; Striberni R
    Clin Pharmacol Ther; 1989 Jan; 45(1):34-40. PubMed ID: 2910636
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Lack of gender differences and large intrasubject variability in cytochrome P450 activity measured by phenotyping with dextromethorphan.
    McCune JS; Lindley C; Decker JL; Williamson KM; Meadowcroft AM; Graff D; Sawyer WT; Blough DK; Pieper JA
    J Clin Pharmacol; 2001 Jul; 41(7):723-31. PubMed ID: 11452704
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 6.