200 related articles for article (PubMed ID: 1309768)
1. Insulin stimulation of phosphatidylinositol 3-kinase activity maps to insulin receptor regions required for endogenous substrate phosphorylation.
Backer JM; Schroeder GG; Kahn CR; Myers MG; Wilden PA; Cahill DA; White MF
J Biol Chem; 1992 Jan; 267(2):1367-74. PubMed ID: 1309768
[TBL] [Abstract][Full Text] [Related]
2. Mutations in the juxtamembrane region of the insulin receptor impair activation of phosphatidylinositol 3-kinase by insulin.
Kapeller R; Chen KS; Yoakim M; Schaffhausen BS; Backer J; White MF; Cantley LC; Ruderman NB
Mol Endocrinol; 1991 Jun; 5(6):769-77. PubMed ID: 1656240
[TBL] [Abstract][Full Text] [Related]
3. The insulin receptor functions normally in Chinese hamster ovary cells after truncation of the C terminus.
Myers MG; Backer JM; Siddle K; White MF
J Biol Chem; 1991 Jun; 266(16):10616-23. PubMed ID: 1645354
[TBL] [Abstract][Full Text] [Related]
4. Enhanced insulin-induced mitogenesis and mitogen-activated protein kinase activities in mutant insulin receptors with substitution of two COOH-terminal tyrosine autophosphorylation sites by phenylalanine.
Ando A; Momomura K; Tobe K; Yamamoto-Honda R; Sakura H; Tamori Y; Kaburagi Y; Koshio O; Akanuma Y; Yazaki Y
J Biol Chem; 1992 Jun; 267(18):12788-96. PubMed ID: 1618780
[TBL] [Abstract][Full Text] [Related]
5. Phosphorylation in vitro of the 85 kDa subunit of phosphatidylinositol 3-kinase and its possible activation by insulin receptor tyrosine kinase.
Hayashi H; Miyake N; Kanai F; Shibasaki F; Takenawa T; Ebina Y
Biochem J; 1991 Dec; 280 ( Pt 3)(Pt 3):769-75. PubMed ID: 1722393
[TBL] [Abstract][Full Text] [Related]
6. Receptor-mediated internalization of insulin requires a 12-amino acid sequence in the juxtamembrane region of the insulin receptor beta-subunit.
Backer JM; Kahn CR; Cahill DA; Ullrich A; White MF
J Biol Chem; 1990 Sep; 265(27):16450-4. PubMed ID: 2204623
[TBL] [Abstract][Full Text] [Related]
7. Phosphatidylinositol kinase or an associated protein is a substrate for the insulin receptor tyrosine kinase.
Endemann G; Yonezawa K; Roth RA
J Biol Chem; 1990 Jan; 265(1):396-400. PubMed ID: 1688432
[TBL] [Abstract][Full Text] [Related]
8. Association of IRS-1 with the insulin receptor and the phosphatidylinositol 3'-kinase. Formation of binary and ternary signaling complexes in intact cells.
Backer JM; Myers MG; Sun XJ; Chin DJ; Shoelson SE; Miralpeix M; White MF
J Biol Chem; 1993 Apr; 268(11):8204-12. PubMed ID: 8385139
[TBL] [Abstract][Full Text] [Related]
9. The level of insulin receptor tyrosine kinase activity modulates the activities of phosphatidylinositol 3-kinase, microtubule-associated protein, and S6 kinases.
Wilden PA; Kahn CR
Mol Endocrinol; 1994 May; 8(5):558-67. PubMed ID: 8058065
[TBL] [Abstract][Full Text] [Related]
10. Cytoplasmic juxtamembrane region of the insulin receptor: a critical role in ATP binding, endogenous substrate phosphorylation, and insulin-stimulated bioeffects in CHO cells.
Backer JM; Schroeder GG; Cahill DA; Ullrich A; Siddle K; White MF
Biochemistry; 1991 Jul; 30(26):6366-72. PubMed ID: 1647198
[TBL] [Abstract][Full Text] [Related]
11. Site-directed mutagenesis of the juxtamembrane domain of the human insulin receptor.
Kaburagi Y; Momomura K; Yamamoto-Honda R; Tobe K; Tamori Y; Sakura H; Akanuma Y; Yazaki Y; Kadowaki T
J Biol Chem; 1993 Aug; 268(22):16610-22. PubMed ID: 8393870
[TBL] [Abstract][Full Text] [Related]
12. Normal insulin receptor substrate-1 phosphorylation in autophosphorylation-defective truncated insulin receptor. Evidence that phosphorylation of substrates might be sufficient for certain biological effects evoked by insulin.
Yamamoto-Honda R; Kadowaki T; Momomura K; Tobe K; Tamori Y; Shibasaki Y; Mori Y; Kaburagi Y; Koshio O; Akanuma Y
J Biol Chem; 1993 Aug; 268(22):16859-65. PubMed ID: 8344965
[TBL] [Abstract][Full Text] [Related]
13. Insulin stimulates tyrosine phosphorylation of multiple high molecular weight substrates in Fao hepatoma cells.
Miralpeix M; Sun XJ; Backer JM; Myers MG; Araki E; White MF
Biochemistry; 1992 Sep; 31(37):9031-9. PubMed ID: 1382584
[TBL] [Abstract][Full Text] [Related]
14. Effect of phosphotyrosyl-IRS-1 level and insulin receptor tyrosine kinase activity on insulin-stimulated phosphatidylinositol 3, MAP, and S6 kinase activities.
Wilden PA; Broadway DE
J Cell Physiol; 1995 Apr; 163(1):9-18. PubMed ID: 7896903
[TBL] [Abstract][Full Text] [Related]
15. The insulin and insulin-like growth factor-I receptor substrate IRS-1 associates with and activates phosphatidylinositol 3-kinase in vitro.
Giorgetti S; Ballotti R; Kowalski-Chauvel A; Tartare S; Van Obberghen E
J Biol Chem; 1993 Apr; 268(10):7358-64. PubMed ID: 8385105
[TBL] [Abstract][Full Text] [Related]
16. Insulin signal transduction by a mutant human insulin receptor lacking the NPEY sequence. Evidence for an alternate mitogenic signaling pathway that is independent of Shc phosphorylation.
Berhanu P; Anderson C; Hickman M; Ciaraldi TP
J Biol Chem; 1997 Sep; 272(36):22884-90. PubMed ID: 9278451
[TBL] [Abstract][Full Text] [Related]
17. Identification of serines-967/968 in the juxtamembrane region of the insulin receptor as insulin-stimulated phosphorylation sites.
Liu F; Roth RA
Biochem J; 1994 Mar; 298 ( Pt 2)(Pt 2):471-7. PubMed ID: 8135757
[TBL] [Abstract][Full Text] [Related]
18. Potentiation of insulin stimulation of phosphatidylinositol 3-kinase by thiazolidinedione-derived antidiabetic agents in Chinese hamster ovary cells expressing human insulin receptors and L6 myotubes.
Zhang B; Szalkowski D; Diaz E; Hayes N; Smith R; Berger J
J Biol Chem; 1994 Oct; 269(41):25735-41. PubMed ID: 7929278
[TBL] [Abstract][Full Text] [Related]
19. Insulin receptor kinase domain autophosphorylation regulates receptor enzymatic function.
Wilden PA; Kahn CR; Siddle K; White MF
J Biol Chem; 1992 Aug; 267(23):16660-8. PubMed ID: 1322912
[TBL] [Abstract][Full Text] [Related]
20. Insulin-mimetic anti-insulin receptor monoclonal antibodies stimulate receptor kinase activity in intact cells.
Steele-Perkins G; Roth RA
J Biol Chem; 1990 Jun; 265(16):9458-63. PubMed ID: 1693150
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
