524 related articles for article (PubMed ID: 1312898)
1. Metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in human lung and liver microsomes and cytochromes P-450 expressed in hepatoma cells.
Smith TJ; Guo Z; Gonzalez FJ; Guengerich FP; Stoner GD; Yang CS
Cancer Res; 1992 Apr; 52(7):1757-63. PubMed ID: 1312898
[TBL] [Abstract][Full Text] [Related]
2. Kinetic analysis of the activation of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone by heterologously expressed human P450 enzymes and the effect of P450-specific chemical inhibitors on this activation in human liver microsomes.
Patten CJ; Smith TJ; Murphy SE; Wang MH; Lee J; Tynes RE; Koch P; Yang CS
Arch Biochem Biophys; 1996 Sep; 333(1):127-38. PubMed ID: 8806763
[TBL] [Abstract][Full Text] [Related]
3. Activation of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) in human lung microsomes by cytochromes P450, lipoxygenase, and hydroperoxides.
Smith TJ; Stoner GD; Yang CS
Cancer Res; 1995 Dec; 55(23):5566-73. PubMed ID: 7585636
[TBL] [Abstract][Full Text] [Related]
4. Metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone by inducible and constitutive cytochrome P450 enzymes in rats.
Guo Z; Smith TJ; Thomas PE; Yang CS
Arch Biochem Biophys; 1992 Oct; 298(1):279-86. PubMed ID: 1524438
[TBL] [Abstract][Full Text] [Related]
5. Enzymes involved in the bioactivation of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in patas monkey lung and liver microsomes.
Smith TJ; Liao AM; Liu Y; Jones AB; Anderson LM; Yang CS
Carcinogenesis; 1997 Aug; 18(8):1577-84. PubMed ID: 9276633
[TBL] [Abstract][Full Text] [Related]
6. Metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) by human cytochrome P450 1A2 and its inhibition by phenethyl isothiocyanate.
Smith TJ; Guo Z; Guengerich FP; Yang CS
Carcinogenesis; 1996 Apr; 17(4):809-13. PubMed ID: 8625495
[TBL] [Abstract][Full Text] [Related]
7. Metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in mouse lung microsomes and its inhibition by isothiocyanates.
Smith TJ; Guo ZY; Thomas PE; Chung FL; Morse MA; Elkind K; Yang CS
Cancer Res; 1990 Nov; 50(21):6817-22. PubMed ID: 2208146
[TBL] [Abstract][Full Text] [Related]
8. Metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) by cytochrome P450IIB1 in a reconstituted system.
Guo Z; Smith TJ; Ishizaki H; Yang CS
Carcinogenesis; 1991 Dec; 12(12):2277-82. PubMed ID: 1747927
[TBL] [Abstract][Full Text] [Related]
9. Mechanisms of inhibition of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone bioactivation in mouse by dietary phenethyl isothiocyanate.
Smith TJ; Guo Z; Li C; Ning SM; Thomas PE; Yang CS
Cancer Res; 1993 Jul; 53(14):3276-82. PubMed ID: 8324738
[TBL] [Abstract][Full Text] [Related]
10. Kinetics and enzyme involvement in the metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) in microsomes of rat lung and nasal mucosa.
Smith TJ; Guo Z; Hong JY; Ning SM; Thomas PE; Yang CS
Carcinogenesis; 1992 Aug; 13(8):1409-14. PubMed ID: 1499091
[TBL] [Abstract][Full Text] [Related]
11. Comparative metabolism of the tobacco-related carcinogens benzo[a]pyrene, 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone, 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol, and N'- nitrosonornicotine in human hepatic microsomes.
Staretz ME; Murphy SE; Patten CJ; Nunes MG; Koehl W; Amin S; Koenig LA; Guengerich FP; Hecht SS
Drug Metab Dispos; 1997 Feb; 25(2):154-62. PubMed ID: 9029045
[TBL] [Abstract][Full Text] [Related]
12. Biotransformation of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) in peripheral human lung microsomes.
Smith GB; Bend JR; Bedard LL; Reid KR; Petsikas D; Massey TE
Drug Metab Dispos; 2003 Sep; 31(9):1134-41. PubMed ID: 12920169
[TBL] [Abstract][Full Text] [Related]
13. Metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) in human placental microsomes.
Collazo NR; Sultatos LG
Biochem Pharmacol; 1995 Nov; 50(11):1933-41. PubMed ID: 8615875
[TBL] [Abstract][Full Text] [Related]
14. Effect of tobacco smoke condensate on the metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone by adult and fetal hamster microsomes.
Jorquera R; Castonguay A; Schuller HM
Drug Metab Dispos; 1993; 21(2):318-24. PubMed ID: 8097703
[TBL] [Abstract][Full Text] [Related]
15. Metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK), a tobacco-specific carcinogen, by rabbit nasal microsomes and cytochrome P450s NMa and NMb.
Hong JY; Ding X; Smith TJ; Coon MJ; Yang CS
Carcinogenesis; 1992 Nov; 13(11):2141-4. PubMed ID: 1423886
[TBL] [Abstract][Full Text] [Related]
16. 11Beta-hydroxysteroid dehydrogenase responsible for carbonyl reduction of the tobacco-specific nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in mouse lung microsomes.
Maser E
Cancer Res; 1998 Jul; 58(14):2996-3003. PubMed ID: 9679962
[TBL] [Abstract][Full Text] [Related]
17. Metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) in isolated rat lung and liver.
Schrader E; Hirsch-Ernst KI; Richter E; Foth H
Naunyn Schmiedebergs Arch Pharmacol; 1998 Mar; 357(3):336-43. PubMed ID: 9550307
[TBL] [Abstract][Full Text] [Related]
18. Human cervical tissue metabolizes the tobacco-specific nitrosamine, 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone, via alpha-hydroxylation and carbonyl reduction pathways.
Prokopczyk B; Trushin N; Leszczynska J; Waggoner SE; El-Bayoumy K
Carcinogenesis; 2001 Jan; 22(1):107-14. PubMed ID: 11159748
[TBL] [Abstract][Full Text] [Related]
19. Biotransformation of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in lung tissue from mouse, rat, hamster, and man.
Richter E; Engl J; Friesenegger S; Tricker AR
Chem Res Toxicol; 2009 Jun; 22(6):1008-17. PubMed ID: 19408892
[TBL] [Abstract][Full Text] [Related]
20. Effects of pregnancy and ethanol treatment on the metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone by hamster liver and lung microsomes.
Jorquera R; Castonguay A; Schuller HM
Drug Metab Dispos; 1992; 20(4):510-7. PubMed ID: 1356727
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]