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2. Characterization of two 85 kd proteins that associate with receptor tyrosine kinases, middle-T/pp60c-src complexes, and PI3-kinase. Otsu M; Hiles I; Gout I; Fry MJ; Ruiz-Larrea F; Panayotou G; Thompson A; Dhand R; Hsuan J; Totty N Cell; 1991 Apr; 65(1):91-104. PubMed ID: 1707345 [TBL] [Abstract][Full Text] [Related]
3. Expression and characterization of the p85 subunit of the phosphatidylinositol 3-kinase complex and a related p85 beta protein by using the baculovirus expression system. Gout I; Dhand R; Panayotou G; Fry MJ; Hiles I; Otsu M; Waterfield MD Biochem J; 1992 Dec; 288 ( Pt 2)(Pt 2):395-405. PubMed ID: 1334406 [TBL] [Abstract][Full Text] [Related]
4. Structure and function of phosphatidylinositol 3-kinase: a potential second messenger system involved in growth control. Fry MJ; Waterfield MD Philos Trans R Soc Lond B Biol Sci; 1993 Jun; 340(1293):337-44. PubMed ID: 8103937 [TBL] [Abstract][Full Text] [Related]
5. Cloning and mutagenesis of the p110 alpha subunit of human phosphoinositide 3'-hydroxykinase. Stirdivant SM; Ahern J; Conroy RR; Barnett SF; Ledder LM; Oliff A; Heimbrook DC Bioorg Med Chem; 1997 Jan; 5(1):65-74. PubMed ID: 9043658 [TBL] [Abstract][Full Text] [Related]
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8. Purification and characterization of a phosphatidylinositol 3-kinase complex from bovine brain by using phosphopeptide affinity columns. Fry MJ; Panayotou G; Dhand R; Ruiz-Larrea F; Gout I; Nguyen O; Courtneidge SA; Waterfield MD Biochem J; 1992 Dec; 288 ( Pt 2)(Pt 2):383-93. PubMed ID: 1281404 [TBL] [Abstract][Full Text] [Related]
10. Biochemical characterization of the free catalytic p110 alpha and the complexed heterodimeric p110 alpha.p85 alpha forms of the mammalian phosphatidylinositol 3-kinase. Woscholski R; Dhand R; Fry MJ; Waterfield MD; Parker PJ J Biol Chem; 1994 Oct; 269(40):25067-72. PubMed ID: 7929193 [TBL] [Abstract][Full Text] [Related]
11. A biosensor approach to probe the structure and function of the p85 alpha subunit of the phosphatidylinositol 3-kinase complex. End P; Gout I; Fry MJ; Panayotou G; Dhand R; Yonezawa K; Kasuga M; Waterfield MD J Biol Chem; 1993 May; 268(14):10066-75. PubMed ID: 7683666 [TBL] [Abstract][Full Text] [Related]
12. A region of the 85-kilodalton (kDa) subunit of phosphatidylinositol 3-kinase binds the 110-kDa catalytic subunit in vivo. Klippel A; Escobedo JA; Hu Q; Williams LT Mol Cell Biol; 1993 Sep; 13(9):5560-6. PubMed ID: 8395006 [TBL] [Abstract][Full Text] [Related]
13. Schizosaccharomyces pombe Vps34p, a phosphatidylinositol-specific PI 3-kinase essential for normal cell growth and vacuole morphology. Takegawa K; DeWald DB; Emr SD J Cell Sci; 1995 Dec; 108 ( Pt 12)():3745-56. PubMed ID: 8719881 [TBL] [Abstract][Full Text] [Related]
14. Cloning of PI3 kinase-associated p85 utilizing a novel method for expression/cloning of target proteins for receptor tyrosine kinases. Skolnik EY; Margolis B; Mohammadi M; Lowenstein E; Fischer R; Drepps A; Ullrich A; Schlessinger J Cell; 1991 Apr; 65(1):83-90. PubMed ID: 1849461 [TBL] [Abstract][Full Text] [Related]
15. A human phosphatidylinositol 3-kinase complex related to the yeast Vps34p-Vps15p protein sorting system. Volinia S; Dhand R; Vanhaesebroeck B; MacDougall LK; Stein R; Zvelebil MJ; Domin J; Panaretou C; Waterfield MD EMBO J; 1995 Jul; 14(14):3339-48. PubMed ID: 7628435 [TBL] [Abstract][Full Text] [Related]
16. cDNA cloning of a novel 85 kd protein that has SH2 domains and regulates binding of PI3-kinase to the PDGF beta-receptor. Escobedo JA; Navankasattusas S; Kavanaugh WM; Milfay D; Fried VA; Williams LT Cell; 1991 Apr; 65(1):75-82. PubMed ID: 1849460 [TBL] [Abstract][Full Text] [Related]
18. The catalytic subunit of phosphatidylinositol 3-kinase is a substrate for the activated platelet-derived growth factor receptor, but not for middle-T antigen-pp60c-src complexes. Roche S; Dhand R; Waterfield MD; Courtneidge SA Biochem J; 1994 Aug; 301 ( Pt 3)(Pt 3):703-11. PubMed ID: 7519847 [TBL] [Abstract][Full Text] [Related]
19. Tyrosine phosphorylation of the catalytic subunit p110 of phosphatidylinositol-3 kinase induced by HMG-CoA reductase inhibitor inhibits its kinase activity in L6 myoblasts. Nakagawa H; Mutoh T; Kumano T; Kuriyama M FEBS Lett; 2001 Nov; 508(1):53-6. PubMed ID: 11707267 [TBL] [Abstract][Full Text] [Related]
20. Regulation of the p85/p110 phosphatidylinositol 3'-kinase: stabilization and inhibition of the p110alpha catalytic subunit by the p85 regulatory subunit. Yu J; Zhang Y; McIlroy J; Rordorf-Nikolic T; Orr GA; Backer JM Mol Cell Biol; 1998 Mar; 18(3):1379-87. PubMed ID: 9488453 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]