125 related articles for article (PubMed ID: 1331447)
1. Development of a novel series of styrylquinoline compounds as high-affinity leukotriene D4 receptor antagonists: synthetic and structure-activity studies leading to the discovery of (+-)-3-[[[3-[2-(7-chloro-2-quinolinyl)-(E)-ethenyl]phenyl][[3- (dimethylamino)-3-oxopropyl]thio]methyl]thio]propionic acid.
Zamboni R; Belley M; Champion E; Charette L; DeHaven R; Frenette R; Gauthier JY; Jones TR; Leger S; Masson P
J Med Chem; 1992 Oct; 35(21):3832-44. PubMed ID: 1331447
[TBL] [Abstract][Full Text] [Related]
2. Stereospecific synthesis, assignment of absolute configuration, and biological activity of the enantiomers of 3-[[[3-[2-(7-chloroquinolin-2-yl)-(E)-ethenyl]phenyl] [[3-(dimethylamino)-3-oxopropyl]thio]methyl]thio]propionic acid, a potent and specific leukotriene D4 receptor antagonist.
Gauthier JY; Jones T; Champion E; Charette L; Dehaven R; Ford-Hutchinson AW; Hoogsteen K; Lord A; Masson P; Piechuta H
J Med Chem; 1990 Oct; 33(10):2841-5. PubMed ID: 2170650
[TBL] [Abstract][Full Text] [Related]
3. Pharmacology of the leukotriene antagonist verlukast: the (R)-enantiomer of MK-571.
Jones TR; Zamboni R; Belley M; Champion E; Charette L; Ford-Hutchinson AW; Gauthier JY; Leger S; Lord A; Masson P
Can J Physiol Pharmacol; 1991 Dec; 69(12):1847-54. PubMed ID: 1666333
[TBL] [Abstract][Full Text] [Related]
4. Pharmacology of L-660,711 (MK-571): a novel potent and selective leukotriene D4 receptor antagonist.
Jones TR; Zamboni R; Belley M; Champion E; Charette L; Ford-Hutchinson AW; Frenette R; Gauthier JY; Leger S; Masson P
Can J Physiol Pharmacol; 1989 Jan; 67(1):17-28. PubMed ID: 2540892
[TBL] [Abstract][Full Text] [Related]
5. Pharmacology of montelukast sodium (Singulair), a potent and selective leukotriene D4 receptor antagonist.
Jones TR; Labelle M; Belley M; Champion E; Charette L; Evans J; Ford-Hutchinson AW; Gauthier JY; Lord A; Masson P
Can J Physiol Pharmacol; 1995 Feb; 73(2):191-201. PubMed ID: 7621356
[TBL] [Abstract][Full Text] [Related]
6. The development of a novel series of (quinolin-2-ylmethoxy)phenyl-containing compounds as high-affinity leukotriene receptor antagonists. 3. Structural variation of the acidic side chain to give antagonists of enhanced potency.
Galemmo RA; Johnson WH; Learn KS; Lee TD; Huang FC; Campbell HF; Youssefyeh R; O'Rourke SV; Schuessler G; Sweeney DM
J Med Chem; 1990 Oct; 33(10):2828-41. PubMed ID: 2170649
[TBL] [Abstract][Full Text] [Related]
7. Synthesis and structure-activity relationships of carboxyflavones as structurally rigid CysLT1 (LTD4) receptor antagonists.
Zwaagstra ME; Timmerman H; van de Stolpe AC; de Kanter FJ; Tamura M; Wada Y; Zhang MQ
J Med Chem; 1998 Apr; 41(9):1428-38. PubMed ID: 9554876
[TBL] [Abstract][Full Text] [Related]
8. Optimization of the quinoline and substituted benzyl moieties of a series of phenyltetrazole leukotriene D4 receptor antagonists.
Sawyer JS; Baldwin RF; Rinkema LE; Roman CR; Fleisch JH
J Med Chem; 1992 Apr; 35(7):1200-9. PubMed ID: 1313877
[TBL] [Abstract][Full Text] [Related]
9. Development of a novel series of (2-quinolinylmethoxy)phenyl-containing compounds as high-affinity leukotriene D4 receptor antagonists. 4. Addition of chromone moiety enhances leukotriene D4 receptor binding affinity.
Huang FC; Galemmo RA; Poli GB; Learn KS; Morrissette MM; Johnson WH; Dankulich WP; Campbell HF; Carnathan GW; VanInwegen RG
J Med Chem; 1991 May; 34(5):1704-7. PubMed ID: 1851845
[TBL] [Abstract][Full Text] [Related]
10. Discovery of OT4003, a novel, potent, and orally active cys-LT1 receptor antagonist.
Tvaermose-Nielsen O; Rachlin S; Dannacher H; Björkling F; Kirstein D; Bramm E; Nielsen CK; Mortensen JT; Binderup L
Bioorg Med Chem; 1997 Feb; 5(2):415-27. PubMed ID: 9061206
[TBL] [Abstract][Full Text] [Related]
11. Binding of radiolabeled high affinity antagonist to leukotriene D4 receptor in guinea pig lung membranes: interconversion of agonist-receptor binding affinity states.
O'Sullivan BP; Mong S
Mol Pharmacol; 1989 Jun; 35(6):795-802. PubMed ID: 2543913
[TBL] [Abstract][Full Text] [Related]
12. Synthesis and structure-activity relationships of carboxylated chalcones: a novel series of CysLT1 (LTD4) receptor antagonists.
Zwaagstra ME; Timmerman H; Tamura M; Tohma T; Wada Y; Onogi K; Zhang MQ
J Med Chem; 1997 Mar; 40(7):1075-89. PubMed ID: 9089329
[TBL] [Abstract][Full Text] [Related]
13. Immediate hypersensitivity reactions in the guinea-pig conjunctiva: studies with a second-generation leukotriene D4 receptor antagonist, MK-571.
Chan CC; Dagenais F; Firby P; Foster A; Ford-Hutchinson AW
Can J Physiol Pharmacol; 1989 Aug; 67(8):845-50. PubMed ID: 2557140
[TBL] [Abstract][Full Text] [Related]
14. Characterization of the leukotriene D4 receptor in hyperreactive rat lung.
Metters KM; Frey EA; Ford-Hutchinson AW
Eur J Pharmacol; 1991 Feb; 194(1):51-61. PubMed ID: 1647964
[TBL] [Abstract][Full Text] [Related]
15. Development of a novel series of (2-quinolinylmethoxy)phenyl-containing compounds as high-affinity leukotriene receptor antagonists. 1. Initial structure-activity relationships.
Youssefyeh RD; Magnien E; Lee TD; Chan WK; Lin CJ; Galemmo RA; Johnson WH; Tan J; Campbell HF; Huang FC
J Med Chem; 1990 Apr; 33(4):1186-94. PubMed ID: 2157009
[TBL] [Abstract][Full Text] [Related]
16. N-[(arylmethoxy)phenyl] carboxylic acids, hydroxamic acids, tetrazoles, and sulfonyl carboxamides. Potent orally active leukotriene D4 antagonists of novel structure.
Musser JH; Kreft AF; Bender RH; Kubrak DM; Grimes D; Carlson RP; Hand JM; Chang J
J Med Chem; 1990 Jan; 33(1):240-5. PubMed ID: 2104935
[TBL] [Abstract][Full Text] [Related]
17. Characterization of the leukotriene D4 receptor in dimethylsulphoxide-differentiated U937 cells: comparison with the leukotriene D4 receptor in human lung and guinea-pig lung.
Frey EA; Nicholson DW; Metters KM
Eur J Pharmacol; 1993 Feb; 244(3):239-50. PubMed ID: 8384568
[TBL] [Abstract][Full Text] [Related]
18. (Phenylmethoxy)phenyl derivatives of omega-oxo- and omega-tetrazolylalkanoic acids and related tetrazoles. Synthesis and evaluation as leukotriene D4 receptor antagonists.
Dillard RD; Hahn RA; McCullough D; Carr FP; Rinkema LE; Roman CR; Fleisch JH
J Med Chem; 1991 Sep; 34(9):2768-78. PubMed ID: 1654427
[TBL] [Abstract][Full Text] [Related]
19. Pharmacologic actions of Ro 24-5913, a novel antagonist of leukotriene D4.
O'Donnell M; Crowley HJ; Yaremko B; O'Neill N; Welton AF
J Pharmacol Exp Ther; 1991 Nov; 259(2):751-8. PubMed ID: 1658310
[TBL] [Abstract][Full Text] [Related]
20. Characterisation of leukotriene receptors on rat lung strip.
Norman P; Abram TS; Cuthbert NJ; Tudhope SR; Gardiner PJ
Eur J Pharmacol; 1994 Dec; 271(1):73-8. PubMed ID: 7698214
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]