178 related articles for article (PubMed ID: 1358068)
1. P-glycoprotein possesses a 1,4-dihydropyridine-selective drug acceptor site which is alloserically coupled to a vinca-alkaloid-selective binding site.
Ferry DR; Russell MA; Cullen MH
Biochem Biophys Res Commun; 1992 Oct; 188(1):440-5. PubMed ID: 1358068
[TBL] [Abstract][Full Text] [Related]
2. Allosteric regulation of [3H]vinblastine binding to P-glycoprotein of MCF-7 ADR cells by dexniguldipine.
Ferry DR; Malkhandi PJ; Russell MA; Kerr DJ
Biochem Pharmacol; 1995 Jun; 49(12):1851-61. PubMed ID: 7598747
[TBL] [Abstract][Full Text] [Related]
3. Dexniguldipine-HCl is a potent allosteric inhibitor of [3H]vinblastine binding to P-glycoprotein of CCRF ADR 5000 cells.
Malkhandi J; Ferry DR; Boer R; Gekeler V; Ise W; Kerr DJ
Eur J Pharmacol; 1994 Dec; 288(1):105-14. PubMed ID: 7705462
[TBL] [Abstract][Full Text] [Related]
4. Azidopine noncompetitively interacts with vinblastine and cyclosporin A binding to P-glycoprotein in multidrug resistant cells.
Tamai I; Safa AR
J Biol Chem; 1991 Sep; 266(25):16796-800. PubMed ID: 1679434
[TBL] [Abstract][Full Text] [Related]
5. Localization of the 1,4-dihydropyridine drug acceptor of P-glycoprotein to a cytoplasmic domain using a permanently charged derivative N-methyl dexniguldipine.
Ferry D; Boer R; Callaghan R; Ulrich WR
Int J Clin Pharmacol Ther; 2000 Mar; 38(3):130-40. PubMed ID: 10739116
[TBL] [Abstract][Full Text] [Related]
6. Multidrug resistance transporter P-glycoprotein has distinct but interacting binding sites for cytotoxic drugs and reversing agents.
Pascaud C; Garrigos M; Orlowski S
Biochem J; 1998 Jul; 333 ( Pt 2)(Pt 2):351-8. PubMed ID: 9657975
[TBL] [Abstract][Full Text] [Related]
7. N-(p-azido-3-[125I]iodophenethyl)spiperone binds to specific regions of P-glycoprotein and another multidrug binding protein, spiperophilin, in human neuroblastoma cells.
Safa AR; Agresti M; Bryk D; Tamai I
Biochemistry; 1994 Jan; 33(1):256-65. PubMed ID: 7904476
[TBL] [Abstract][Full Text] [Related]
8. Agents which reverse multidrug-resistance are inhibitors of [3H]vinblastine transport by isolated vesicles.
Horio M; Lovelace E; Pastan I; Gottesman MM
Biochim Biophys Acta; 1991 Jan; 1061(1):106-10. PubMed ID: 1671642
[TBL] [Abstract][Full Text] [Related]
9. Characterization of the azidopine and vinblastine binding site of P-glycoprotein.
Bruggemann EP; Currier SJ; Gottesman MM; Pastan I
J Biol Chem; 1992 Oct; 267(29):21020-6. PubMed ID: 1356986
[TBL] [Abstract][Full Text] [Related]
10. Progesterone interacts with P-glycoprotein in multidrug-resistant cells and in the endometrium of gravid uterus.
Yang CP; DePinho SG; Greenberger LM; Arceci RJ; Horwitz SB
J Biol Chem; 1989 Jan; 264(2):782-8. PubMed ID: 2562956
[TBL] [Abstract][Full Text] [Related]
11. Stereoisomers of calcium antagonists which differ markedly in their potencies as calcium blockers are equally effective in modulating drug transport by P-glycoprotein.
Höllt V; Kouba M; Dietel M; Vogt G
Biochem Pharmacol; 1992 Jun; 43(12):2601-8. PubMed ID: 1352973
[TBL] [Abstract][Full Text] [Related]
12. Functional studies of P-glycoprotein in inside-out plasma membrane vesicles derived from murine erythroleukemia cells overexpressing MDR 3. Properties and kinetics of the interaction of vinblastine with P-glycoprotein and evidence for its active mediated transport.
Schlemmer SR; Sirotnak FM
J Biol Chem; 1994 Dec; 269(49):31059-66. PubMed ID: 7983045
[TBL] [Abstract][Full Text] [Related]
13. Competitive interaction of cyclosporins with the Vinca alkaloid-binding site of P-glycoprotein in multidrug-resistant cells.
Tamai I; Safa AR
J Biol Chem; 1990 Sep; 265(27):16509-13. PubMed ID: 1975813
[TBL] [Abstract][Full Text] [Related]
14. Modulation of P-glycoprotein-mediated drug transport by alterations in lipid fluidity of rat liver canalicular membrane vesicles.
Sinicrope FA; Dudeja PK; Bissonnette BM; Safa AR; Brasitus TA
J Biol Chem; 1992 Dec; 267(35):24995-5002. PubMed ID: 1360981
[TBL] [Abstract][Full Text] [Related]
15. Modulators of the multidrug-transporter, P-glycoprotein, exist in the human plasma.
Ichikawa M; Yoshimura A; Furukawa T; Sumizawa T; Akiyama S
Biochem Biophys Res Commun; 1990 Jan; 166(1):74-80. PubMed ID: 1967939
[TBL] [Abstract][Full Text] [Related]
16. BIBW22 BS, potent multidrug resistance-reversing agent, binds directly to P-glycoprotein and accumulates in drug-resistant cells.
Liu Z; Lheureux F; Pouliot JF; Heckel A; Bamberger U; Georges E
Mol Pharmacol; 1996 Sep; 50(3):482-92. PubMed ID: 8794885
[TBL] [Abstract][Full Text] [Related]
17. Interaction of tamoxifen with the multidrug resistance P-glycoprotein.
Callaghan R; Higgins CF
Br J Cancer; 1995 Feb; 71(2):294-9. PubMed ID: 7841043
[TBL] [Abstract][Full Text] [Related]
18. The multi-drug resistance reversal agent SR33557 and modulation of vinca alkaloid binding to P-glycoprotein by an allosteric interaction.
Martin C; Berridge G; Higgins CF; Callaghan R
Br J Pharmacol; 1997 Oct; 122(4):765-71. PubMed ID: 9375975
[TBL] [Abstract][Full Text] [Related]
19. Reversal of P-glycoprotein-associated multidrug resistance by ivermectin.
Pouliot JF; L'Heureux F; Liu Z; Prichard RK; Georges E
Biochem Pharmacol; 1997 Jan; 53(1):17-25. PubMed ID: 8960059
[TBL] [Abstract][Full Text] [Related]
20. Two pyridine analogues with more effective ability to reverse multidrug resistance and with lower calcium channel blocking activity than their dihydropyridine counterparts.
Shudo N; Mizoguchi T; Kiyosue T; Arita M; Yoshimura A; Seto K; Sakoda R; Akiyama S
Cancer Res; 1990 May; 50(10):3055-61. PubMed ID: 1970752
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
