164 related articles for article (PubMed ID: 13679061)
1. Structural basis for inhibition of human PNP by immucillin-H.
Filgueira de Azevedo W; Canduri F; Marangoni dos Santos D; Pereira JH; Dias MV; Silva RG; Mendes MA; Basso LA; Palma MS; Santos DS
Biochem Biophys Res Commun; 2003 Oct; 309(4):917-22. PubMed ID: 13679061
[TBL] [Abstract][Full Text] [Related]
2. Assignment of downfield proton resonances in purine nucleoside phosphorylase immucillin-H complex by saturation-transferred NOEs.
Deng H; Lewandowicz A; Cahill SM; Furneaux RH; Tyler PC; Girvin ME; Callender RH; Schramm VL
Biochemistry; 2004 Feb; 43(7):1980-7. PubMed ID: 14967038
[TBL] [Abstract][Full Text] [Related]
3. New catalytic mechanism for human purine nucleoside phosphorylase.
Canduri F; Fadel V; Basso LA; Palma MS; Santos DS; de Azevedo WF
Biochem Biophys Res Commun; 2005 Feb; 327(3):646-9. PubMed ID: 15649395
[TBL] [Abstract][Full Text] [Related]
4. Transition state structure of purine nucleoside phosphorylase and principles of atomic motion in enzymatic catalysis.
Fedorov A; Shi W; Kicska G; Fedorov E; Tyler PC; Furneaux RH; Hanson JC; Gainsford GJ; Larese JZ; Schramm VL; Almo SC
Biochemistry; 2001 Jan; 40(4):853-60. PubMed ID: 11170405
[TBL] [Abstract][Full Text] [Related]
5. Structures of purine nucleoside phosphorylase from Mycobacterium tuberculosis in complexes with immucillin-H and its pieces.
Shi W; Basso LA; Santos DS; Tyler PC; Furneaux RH; Blanchard JS; Almo SC; Schramm VL
Biochemistry; 2001 Jul; 40(28):8204-15. PubMed ID: 11444966
[TBL] [Abstract][Full Text] [Related]
6. Crystal structure of human PNP complexed with guanine.
de Azevedo WF; Canduri F; dos Santos DM; Pereira JH; Bertacine Dias MV; Silva RG; Mendes MA; Basso LA; Palma MS; Santos DS
Biochem Biophys Res Commun; 2003 Dec; 312(3):767-72. PubMed ID: 14680831
[TBL] [Abstract][Full Text] [Related]
7. Structure of human PNP complexed with ligands.
Canduri F; Silva RG; dos Santos DM; Palma MS; Basso LA; Santos DS; de Azevedo WF
Acta Crystallogr D Biol Crystallogr; 2005 Jul; 61(Pt 7):856-62. PubMed ID: 15983407
[TBL] [Abstract][Full Text] [Related]
8. The transition state analog inhibitor of Purine Nucleoside Phosphorylase (PNP) Immucillin-H arrests bone loss in rat periodontal disease models.
Deves C; de Assunção TM; Ducati RG; Campos MM; Basso LA; Santos DS; Batista EL
Bone; 2013 Jan; 52(1):167-75. PubMed ID: 23026564
[TBL] [Abstract][Full Text] [Related]
9. Immucillin H, a powerful transition-state analog inhibitor of purine nucleoside phosphorylase, selectively inhibits human T lymphocytes.
Kicska GA; Long L; Hörig H; Fairchild C; Tyler PC; Furneaux RH; Schramm VL; Kaufman HL
Proc Natl Acad Sci U S A; 2001 Apr; 98(8):4593-8. PubMed ID: 11287638
[TBL] [Abstract][Full Text] [Related]
10. Atomic dissection of the hydrogen bond network for transition-state analogue binding to purine nucleoside phosphorylase.
Kicska GA; Tyler PC; Evans GB; Furneaux RH; Shi W; Fedorov A; Lewandowicz A; Cahill SM; Almo SC; Schramm VL
Biochemistry; 2002 Dec; 41(49):14489-98. PubMed ID: 12463747
[TBL] [Abstract][Full Text] [Related]
11. Determining the structural basis for specificity of ligands using crystallographic screening.
de Azevedo WF; Canduri F; Basso LA; Palma MS; Santos DS
Cell Biochem Biophys; 2006; 44(3):405-11. PubMed ID: 16679527
[TBL] [Abstract][Full Text] [Related]
12. Crystal structure of human purine nucleoside phosphorylase complexed with acyclovir.
dos Santos DM; Canduri F; Pereira JH; Vinicius Bertacine Dias M; Silva RG; Mendes MA; Palma MS; Basso LA; de Azevedo WF; Santos DS
Biochem Biophys Res Commun; 2003 Aug; 308(3):553-9. PubMed ID: 12914786
[TBL] [Abstract][Full Text] [Related]
13. Conformational states of human purine nucleoside phosphorylase at rest, at work, and with transition state analogues.
Edwards AA; Tipton JD; Brenowitz MD; Emmett MR; Marshall AG; Evans GB; Tyler PC; Schramm VL
Biochemistry; 2010 Mar; 49(9):2058-67. PubMed ID: 20108972
[TBL] [Abstract][Full Text] [Related]
14. Purine-less death in Plasmodium falciparum induced by immucillin-H, a transition state analogue of purine nucleoside phosphorylase.
Kicska GA; Tyler PC; Evans GB; Furneaux RH; Schramm VL; Kim K
J Biol Chem; 2002 Feb; 277(5):3226-31. PubMed ID: 11706018
[TBL] [Abstract][Full Text] [Related]
15. Plasmodium falciparum purine nucleoside phosphorylase: crystal structures, immucillin inhibitors, and dual catalytic function.
Shi W; Ting LM; Kicska GA; Lewandowicz A; Tyler PC; Evans GB; Furneaux RH; Kim K; Almo SC; Schramm VL
J Biol Chem; 2004 Apr; 279(18):18103-6. PubMed ID: 14982926
[TBL] [Abstract][Full Text] [Related]
16. Crystal structure of human purine nucleoside phosphorylase at 2.3A resolution.
de Azevedo WF; Canduri F; dos Santos DM; Silva RG; de Oliveira JS; de Carvalho LP; Basso LA; Mendes MA; Palma MS; Santos DS
Biochem Biophys Res Commun; 2003 Aug; 308(3):545-52. PubMed ID: 12914785
[TBL] [Abstract][Full Text] [Related]
17. Purine nucleoside phosphorylase inhibitor BCX-1777 (Immucillin-H)--a novel potent and orally active immunosuppressive agent.
Bantia S; Miller PJ; Parker CD; Ananth SL; Horn LL; Kilpatrick JM; Morris PE; Hutchison TL; Montgomery JA; Sandhu JS
Int Immunopharmacol; 2001 Jun; 1(6):1199-210. PubMed ID: 11407314
[TBL] [Abstract][Full Text] [Related]
18. Development of transition state analogues of purine nucleoside phosphorylase as anti-T-cell agents.
Schramm VL
Biochim Biophys Acta; 2002 Jul; 1587(2-3):107-17. PubMed ID: 12084452
[TBL] [Abstract][Full Text] [Related]
19. Over-the-barrier transition state analogues and crystal structure with Mycobacterium tuberculosis purine nucleoside phosphorylase.
Lewandowicz A; Shi W; Evans GB; Tyler PC; Furneaux RH; Basso LA; Santos DS; Almo SC; Schramm VL
Biochemistry; 2003 May; 42(20):6057-66. PubMed ID: 12755607
[TBL] [Abstract][Full Text] [Related]
20. Anopheles gambiae purine nucleoside phosphorylase: catalysis, structure, and inhibition.
Taylor EA; Rinaldo-Matthis A; Li L; Ghanem M; Hazleton KZ; Cassera MB; Almo SC; Schramm VL
Biochemistry; 2007 Oct; 46(43):12405-15. PubMed ID: 17918964
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]