BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

188 related articles for article (PubMed ID: 13679864)

  • 1. Farnesyltransferase inhibitors are potent lung cancer chemopreventive agents in A/J mice with a dominant-negative p53 and/or heterozygous deletion of Ink4a/Arf.
    Zhang Z; Wang Y; Lantry LE; Kastens E; Liu G; Hamilton AD; Sebti SM; Lubet RA; You M
    Oncogene; 2003 Sep; 22(40):6257-65. PubMed ID: 13679864
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Mice with alterations in both p53 and Ink4a/Arf display a striking increase in lung tumor multiplicity and progression: differential chemopreventive effect of budesonide in wild-type and mutant A/J mice.
    Wang Y; Zhang Z; Kastens E; Lubet RA; You M
    Cancer Res; 2003 Aug; 63(15):4389-95. PubMed ID: 12907609
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Cancer chemopreventive activity of a mixture of Chinese herbs (antitumor B) in mouse lung tumor models.
    Zhang Z; Wang Y; Yao R; Li J; Yan Y; La Regina M; Lemon WL; Grubbs CJ; Lubet RA; You M
    Oncogene; 2004 May; 23(21):3841-50. PubMed ID: 15021904
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Chemopreventive efficacy of promising farnesyltransferase inhibitors.
    Lantry LE; Zhang Z; Crist KA; Wang Y; Hara M; Zeeck A; Lubet RA; You M
    Exp Lung Res; 2000 Dec; 26(8):773-90. PubMed ID: 11195470
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Both p16(Ink4a) and the p19(Arf)-p53 pathway constrain progression of pancreatic adenocarcinoma in the mouse.
    Bardeesy N; Aguirre AJ; Chu GC; Cheng KH; Lopez LV; Hezel AF; Feng B; Brennan C; Weissleder R; Mahmood U; Hanahan D; Redston MS; Chin L; Depinho RA
    Proc Natl Acad Sci U S A; 2006 Apr; 103(15):5947-52. PubMed ID: 16585505
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Ras CAAX peptidomimetic FTI 276 selectively blocks tumor growth in nude mice of a human lung carcinoma with K-Ras mutation and p53 deletion.
    Sun J; Qian Y; Hamilton AD; Sebti SM
    Cancer Res; 1995 Oct; 55(19):4243-7. PubMed ID: 7671229
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Effect of farnesyltransferase inhibitor FTI-276 on established lung adenomas from A/J mice induced by 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone.
    Lantry LE; Zhang Z; Yao R; Crist KA; Wang Y; Ohkanda J; Hamilton AD; Sebti SM; Lubet RA; You M
    Carcinogenesis; 2000 Jan; 21(1):113-6. PubMed ID: 10607742
    [TBL] [Abstract][Full Text] [Related]  

  • 8. A germ-line p53 mutation accelerates pulmonary tumorigenesis: p53-independent efficacy of chemopreventive agents green tea or dexamethasone/myo-inositol and chemotherapeutic agents taxol or adriamycin.
    Zhang Z; Liu Q; Lantry LE; Wang Y; Kelloff GJ; Anderson MW; Wiseman RW; Lubet RA; You M
    Cancer Res; 2000 Feb; 60(4):901-7. PubMed ID: 10706103
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Tobacco smoke-induced lung tumorigenesis in mutant A/J mice with alterations in K-ras, p53, or Ink4a/Arf.
    Wang Y; Zhang Z; Lubet R; You M
    Oncogene; 2005 Apr; 24(18):3042-9. PubMed ID: 15846305
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Transformation-selective apoptotic program triggered by farnesyltransferase inhibitors requires Bin1.
    DuHadaway JB; Du W; Donover S; Baker J; Liu AX; Sharp DM; Muller AJ; Prendergast GC
    Oncogene; 2003 Jun; 22(23):3578-88. PubMed ID: 12789266
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Obligate roles for p16(Ink4a) and p19(Arf)-p53 in the suppression of murine pancreatic neoplasia.
    Bardeesy N; Morgan J; Sinha M; Signoretti S; Srivastava S; Loda M; Merlino G; DePinho RA
    Mol Cell Biol; 2002 Jan; 22(2):635-43. PubMed ID: 11756558
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Genetic and epigenetic alterations in lung tumors from bitransgenic Ki-rasG12C expressing mice.
    Floyd HS; Jennings-Gee JE; Kock ND; Miller MS
    Mol Carcinog; 2006 Jul; 45(7):506-17. PubMed ID: 16482519
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Ink4a/Arf tumor suppressor does not modulate the degenerative conditions or tumor spectrum of the telomerase-deficient mouse.
    Khoo CM; Carrasco DR; Bosenberg MW; Paik JH; Depinho RA
    Proc Natl Acad Sci U S A; 2007 Mar; 104(10):3931-6. PubMed ID: 17360455
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Prevention of lung cancer progression by bexarotene in mouse models.
    Wang Y; Zhang Z; Yao R; Jia D; Wang D; Lubet RA; You M
    Oncogene; 2006 Mar; 25(9):1320-9. PubMed ID: 16247446
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The role of Ink4a/Arf in ErbB2 mammary gland tumorigenesis.
    D'Amico M; Wu K; Di Vizio D; Reutens AT; Stahl M; Fu M; Albanese C; Russell RG; Muller WJ; White M; Negassa A; Lee HW; DePinho RA; Pestell RG
    Cancer Res; 2003 Jun; 63(12):3395-402. PubMed ID: 12810676
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Farnesyltransferase inhibitor (L-744,832) restores TGF-beta type II receptor expression and enhances radiation sensitivity in K-ras mutant pancreatic cancer cell line MIA PaCa-2.
    Alcock RA; Dey S; Chendil D; Inayat MS; Mohiuddin M; Hartman G; Chatfield LK; Gallicchio VS; Ahmed MM
    Oncogene; 2002 Nov; 21(51):7883-90. PubMed ID: 12420225
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The differential impact of p16(INK4a) or p19(ARF) deficiency on cell growth and tumorigenesis.
    Sharpless NE; Ramsey MR; Balasubramanian P; Castrillon DH; DePinho RA
    Oncogene; 2004 Jan; 23(2):379-85. PubMed ID: 14724566
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Disruption of the Cockayne syndrome B gene impairs spontaneous tumorigenesis in cancer-predisposed Ink4a/ARF knockout mice.
    Lu Y; Lian H; Sharma P; Schreiber-Agus N; Russell RG; Chin L; van der Horst GT; Bregman DB
    Mol Cell Biol; 2001 Mar; 21(5):1810-8. PubMed ID: 11238917
    [TBL] [Abstract][Full Text] [Related]  

  • 19. INK4a/ARF locus alterations in human non-Hodgkin's lymphomas mainly occur in tumors with wild-type p53 gene.
    Pinyol M; Hernández L; Martínez A; Cobo F; Hernández S; Beà S; López-Guillermo A; Nayach I; Palacín A; Nadal A; Fernández PL; Montserrat E; Cardesa A; Campo E
    Am J Pathol; 2000 Jun; 156(6):1987-96. PubMed ID: 10854221
    [TBL] [Abstract][Full Text] [Related]  

  • 20. INK4a-ARF alterations and p53 mutations in primary and consecutive squamous cell carcinoma of the head and neck.
    Weber A; Bellmann U; Bootz F; Wittekind C; Tannapfel A
    Virchows Arch; 2002 Aug; 441(2):133-42. PubMed ID: 12189502
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.