BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

179 related articles for article (PubMed ID: 1374166)

  • 1. Structure of HIV-1 reverse transcriptase/DNA complex at 7 A resolution showing active site locations.
    Arnold E; Jacobo-Molina A; Nanni RG; Williams RL; Lu X; Ding J; Clark AD; Zhang A; Ferris AL; Clark P
    Nature; 1992 May; 357(6373):85-9. PubMed ID: 1374166
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Crystal structures of an N-terminal fragment from Moloney murine leukemia virus reverse transcriptase complexed with nucleic acid: functional implications for template-primer binding to the fingers domain.
    Najmudin S; Coté ML; Sun D; Yohannan S; Montano SP; Gu J; Georgiadis MM
    J Mol Biol; 2000 Feb; 296(2):613-32. PubMed ID: 10669612
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Structure and functional implications of the polymerase active site region in a complex of HIV-1 RT with a double-stranded DNA template-primer and an antibody Fab fragment at 2.8 A resolution.
    Ding J; Das K; Hsiou Y; Sarafianos SG; Clark AD; Jacobo-Molina A; Tantillo C; Hughes SH; Arnold E
    J Mol Biol; 1998 Dec; 284(4):1095-111. PubMed ID: 9837729
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Locations of anti-AIDS drug binding sites and resistance mutations in the three-dimensional structure of HIV-1 reverse transcriptase. Implications for mechanisms of drug inhibition and resistance.
    Tantillo C; Ding J; Jacobo-Molina A; Nanni RG; Boyer PL; Hughes SH; Pauwels R; Andries K; Janssen PA; Arnold E
    J Mol Biol; 1994 Oct; 243(3):369-87. PubMed ID: 7525966
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Effects of mutations in the polymerase domain on the polymerase, RNase H and strand transfer activities of human immunodeficiency virus type 1 reverse transcriptase.
    Gao HQ; Boyer PL; Arnold E; Hughes SH
    J Mol Biol; 1998 Apr; 277(3):559-72. PubMed ID: 9533880
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Crystal structure of bacteriophage T7 RNA polymerase at 3.3 A resolution.
    Sousa R; Chung YJ; Rose JP; Wang BC
    Nature; 1993 Aug; 364(6438):593-9. PubMed ID: 7688864
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Substitution of Asp114 or Arg116 in the fingers domain of moloney murine leukemia virus reverse transcriptase affects interactions with the template-primer resulting in decreased processivity.
    Gu J; Villanueva RA; Snyder CS; Roth MJ; Georgiadis MM
    J Mol Biol; 2001 Jan; 305(2):341-59. PubMed ID: 11124910
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Buried surface analysis of HIV-1 reverse transcriptase p66/p51 heterodimer and its interaction with dsDNA template/primer.
    Ding J; Jacobo-Molina A; Tantillo C; Lu X; Nanni RG; Arnold E
    J Mol Recognit; 1994 Jun; 7(2):157-61. PubMed ID: 7530020
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Protein-nucleic acid interactions and DNA conformation in a complex of human immunodeficiency virus type 1 reverse transcriptase with a double-stranded DNA template-primer.
    Ding J; Hughes SH; Arnold E
    Biopolymers; 1997; 44(2):125-38. PubMed ID: 9354757
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Synthesis and biological evaluation of certain alkenyldiarylmethanes as anti-HIV-1 agents which act as non-nucleoside reverse transcriptase inhibitors.
    Cushman M; Golebiewski WM; Graham L; Turpin JA; Rice WG; Fliakas-Boltz V; Buckheit RW
    J Med Chem; 1996 Aug; 39(16):3217-27. PubMed ID: 8759644
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Similarities and differences in the RNase H activities of human immunodeficiency virus type 1 reverse transcriptase and Moloney murine leukemia virus reverse transcriptase.
    Gao HQ; Sarafianos SG; Arnold E; Hughes SH
    J Mol Biol; 1999 Dec; 294(5):1097-113. PubMed ID: 10600369
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Convergent combination therapy can select viable multidrug-resistant HIV-1 in vitro.
    Larder BA; Kellam P; Kemp SD
    Nature; 1993 Sep; 365(6445):451-3. PubMed ID: 7692302
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Role of glutamine-151 of human immunodeficiency virus type-1 reverse transcriptase in RNA-directed DNA synthesis.
    Kaushik N; Harris D; Rege N; Modak MJ; Yadav PN; Pandey VN
    Biochemistry; 1997 Nov; 36(47):14430-8. PubMed ID: 9398161
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The phenylmethylthiazolylthiourea nonnucleoside reverse transcriptase (RT) inhibitor MSK-076 selects for a resistance mutation in the active site of human immunodeficiency virus type 2 RT.
    Auwerx J; Stevens M; Van Rompay AR; Bird LE; Ren J; De Clercq E; Oberg B; Stammers DK; Karlsson A; Balzarini J
    J Virol; 2004 Jul; 78(14):7427-37. PubMed ID: 15220416
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Effects of the Delta67 complex of mutations in human immunodeficiency virus type 1 reverse transcriptase on nucleoside analog excision.
    Boyer PL; Imamichi T; Sarafianos SG; Arnold E; Hughes SH
    J Virol; 2004 Sep; 78(18):9987-97. PubMed ID: 15331732
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The crystal structure of the monomeric reverse transcriptase from Moloney murine leukemia virus.
    Das D; Georgiadis MM
    Structure; 2004 May; 12(5):819-29. PubMed ID: 15130474
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Pre-steady-state kinetic characterization of wild type and 3'-azido-3'-deoxythymidine (AZT) resistant human immunodeficiency virus type 1 reverse transcriptase: implication of RNA directed DNA polymerization in the mechanism of AZT resistance.
    Kerr SG; Anderson KS
    Biochemistry; 1997 Nov; 36(46):14064-70. PubMed ID: 9369478
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Sequence-specific actinomycin D binding to single-stranded DNA inhibits HIV reverse transcriptase and other polymerases.
    Rill RL; Hecker KH
    Biochemistry; 1996 Mar; 35(11):3525-33. PubMed ID: 8639503
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Structure of HIV-1 reverse transcriptase in a complex with the non-nucleoside inhibitor alpha-APA R 95845 at 2.8 A resolution.
    Ding J; Das K; Tantillo C; Zhang W; Clark AD; Jessen S; Lu X; Hsiou Y; Jacobo-Molina A; Andries K
    Structure; 1995 Apr; 3(4):365-79. PubMed ID: 7542140
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Crystal structure of human immunodeficiency virus type 1 reverse transcriptase complexed with double-stranded DNA at 3.0 A resolution shows bent DNA.
    Jacobo-Molina A; Ding J; Nanni RG; Clark AD; Lu X; Tantillo C; Williams RL; Kamer G; Ferris AL; Clark P
    Proc Natl Acad Sci U S A; 1993 Jul; 90(13):6320-4. PubMed ID: 7687065
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.