These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

131 related articles for article (PubMed ID: 1374646)

  • 1. Effects of analogs of the DNA minor groove binder Hoechst 33258 on topoisomerase II and I mediated activities.
    Beerman TA; McHugh MM; Sigmund R; Lown JW; Rao KE; Bathini Y
    Biochim Biophys Acta; 1992 May; 1131(1):53-61. PubMed ID: 1374646
    [TBL] [Abstract][Full Text] [Related]  

  • 2. DNA minor groove binding agents interfere with topoisomerase II mediated lesions induced by epipodophyllotoxin derivative VM-26 and acridine derivative m-AMSA in nuclei from L1210 cells.
    Woynarowski JM; Sigmund RD; Beerman TA
    Biochemistry; 1989 May; 28(9):3850-5. PubMed ID: 2473776
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Netropsin and bis-netropsin analogs as inhibitors of the catalytic activity of mammalian DNA topoisomerase II and topoisomerase cleavable complexes.
    Beerman TA; Woynarowski JM; Sigmund RD; Gawron LS; Rao KE; Lown JW
    Biochim Biophys Acta; 1991 Aug; 1090(1):52-60. PubMed ID: 1653020
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Various inhibitors of DNA topoisomerases diminish repair-specific DNA incision in UV-irradiated human fibroblasts.
    Thielmann HW; Popanda O; Gersbach H; Gilberg F
    Carcinogenesis; 1993 Nov; 14(11):2341-51. PubMed ID: 8242865
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Effects of minor groove binding drugs on camptothecin-induced DNA lesions in L1210 nuclei.
    McHugh MM; Sigmund RD; Beerman TA
    Biochem Pharmacol; 1990 Feb; 39(4):707-14. PubMed ID: 1689578
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Modulation of topoisomerase II catalytic activity by DNA minor groove binding agents distamycin, Hoechst 33258, and 4',6-diamidine-2-phenylindole.
    Woynarowski JM; McHugh M; Sigmund RD; Beerman TA
    Mol Pharmacol; 1989 Feb; 35(2):177-82. PubMed ID: 2465485
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Subcellular distribution of the alpha and beta topoisomerase II-DNA complexes stabilized by VM-26.
    Danks MK; Qiu J; Catapano CV; Schmidt CA; Beck WT; Fernandes DJ
    Biochem Pharmacol; 1994 Nov; 48(9):1785-95. PubMed ID: 7980648
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Effect of minor groove binding drugs on mammalian topoisomerase I activity.
    McHugh MM; Woynarowski JM; Sigmund RD; Beerman TA
    Biochem Pharmacol; 1989 Jul; 38(14):2323-8. PubMed ID: 2473754
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Topoisomerase-II-mediated lesions in nascent DNA: comparison of the effects of epipodophyllotoxin derivatives, VM-26 and VP-16, and 9-anilinoacridine derivatives, m-AMSA and o-AMSA.
    Woynarowski JM; Sigmund RD; Beerman TA
    Biochim Biophys Acta; 1988 May; 950(1):21-9. PubMed ID: 2833925
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Inhibition of Leishmania donovani promastigote DNA topoisomerase I and human monocyte DNA topoisomerases I and II by antimonial drugs and classical antitopoisomerase agents.
    Walker J; Saravia NG
    J Parasitol; 2004 Oct; 90(5):1155-62. PubMed ID: 15562618
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The function of DNA topoisomerases in UV-induced DNA excision repair: studies with specific inhibitors in permeabilized human fibroblasts.
    Popanda O; Thielmann HW
    Carcinogenesis; 1992 Dec; 13(12):2321-8. PubMed ID: 1335377
    [TBL] [Abstract][Full Text] [Related]  

  • 12. DNA topoisomerase II from mammalian mitochondria is inhibited by the antitumor drugs, m-AMSA and VM-26.
    Lin JH; Castora FJ
    Biochem Biophys Res Commun; 1991 Apr; 176(2):690-7. PubMed ID: 1851000
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Distinct patterns of cell cycle disturbance elicited by compounds interfering with DNA topoisomerase I and II activity.
    Poot M; Hiller KH; Heimpel S; Hoehn H
    Exp Cell Res; 1995 May; 218(1):326-30. PubMed ID: 7537696
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Synthesis, DNA binding, topoisomerase inhibition and cytotoxic properties of 2-chloroethylnitrosourea derivatives of hoechst 33258.
    Bielawski K; Bielawska A; Anchim T; Wołczyński S
    Biol Pharm Bull; 2005 Jun; 28(6):1004-9. PubMed ID: 15930735
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Anthocyanidins modulate the activity of human DNA topoisomerases I and II and affect cellular DNA integrity.
    Habermeyer M; Fritz J; Barthelmes HU; Christensen MO; Larsen MK; Boege F; Marko D
    Chem Res Toxicol; 2005 Sep; 18(9):1395-404. PubMed ID: 16167831
    [TBL] [Abstract][Full Text] [Related]  

  • 16. A role of DNA topoisomerases in the active dissociation of DNA minor groove-ligand complexes. A flow cytometric study of inhibitor effects.
    Smith PJ; Debenham PG; Watson JV
    Mutat Res; 1989 Mar; 217(2):163-72. PubMed ID: 2537463
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Influence of minor groove binders on the eukaryotic topoisomerase II cleavage reaction with 41 base pair model oligonucleotides.
    Bell A; Kittler L; Löber G; Zimmer C
    Invest New Drugs; 1996; 13(4):271-84. PubMed ID: 8824345
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The topoisomerase II inhibitor VM-26 induces marked changes in histone H1 kinase activity, histones H1 and H3 phosphorylation, and chromosome condensation in G2 phase and mitotic BHK cells.
    Roberge M; Th'ng J; Hamaguchi J; Bradbury EM
    J Cell Biol; 1990 Nov; 111(5 Pt 1):1753-62. PubMed ID: 2172257
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Response of purified mitochondrial DNA topoisomerase I from bovine liver to camptothecin and m-AMSA.
    Lin JH; Castora FJ
    Arch Biochem Biophys; 1995 Dec; 324(2):293-9. PubMed ID: 8554321
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Cellular and chromosomal hypersensitivity to DNA crosslinking agents and topoisomerase inhibitors in the radiosensitive Chinese hamster irs mutants: phenotypic similarities to ataxia telangiectasia and Fanconi's anaemia cells.
    Jones NJ; Ellard S; Waters R; Parry EM
    Carcinogenesis; 1993 Dec; 14(12):2487-94. PubMed ID: 8269616
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.