These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

303 related articles for article (PubMed ID: 1376245)

  • 1. Mitogen activated protein (MAP) kinase transforms tau protein into an Alzheimer-like state.
    Drewes G; Lichtenberg-Kraag B; Döring F; Mandelkow EM; Biernat J; Goris J; Dorée M; Mandelkow E
    EMBO J; 1992 Jun; 11(6):2131-8. PubMed ID: 1376245
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Abnormal Alzheimer-like phosphorylation of tau-protein by cyclin-dependent kinases cdk2 and cdk5.
    Baumann K; Mandelkow EM; Biernat J; Piwnica-Worms H; Mandelkow E
    FEBS Lett; 1993 Dec; 336(3):417-24. PubMed ID: 8282104
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Dephosphorylation of tau protein and Alzheimer paired helical filaments by calcineurin and phosphatase-2A.
    Drewes G; Mandelkow EM; Baumann K; Goris J; Merlevede W; Mandelkow E
    FEBS Lett; 1993 Dec; 336(3):425-32. PubMed ID: 8282105
    [TBL] [Abstract][Full Text] [Related]  

  • 4. p44mpk MAP kinase induces Alzheimer type alterations in tau function and in primary hippocampal neurons.
    Lu Q; Soria JP; Wood JG
    J Neurosci Res; 1993 Jul; 35(4):439-44. PubMed ID: 7689658
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Glycogen synthase kinase-3 and the Alzheimer-like state of microtubule-associated protein tau.
    Mandelkow EM; Drewes G; Biernat J; Gustke N; Van Lint J; Vandenheede JR; Mandelkow E
    FEBS Lett; 1992 Dec; 314(3):315-21. PubMed ID: 1334849
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Alzheimer's disease-like phosphorylation of the microtubule-associated protein tau by glycogen synthase kinase-3 in transfected mammalian cells.
    Lovestone S; Reynolds CH; Latimer D; Davis DR; Anderton BH; Gallo JM; Hanger D; Mulot S; Marquardt B; Stabel S
    Curr Biol; 1994 Dec; 4(12):1077-86. PubMed ID: 7704571
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Phosphorylation-dependent epitopes of neurofilament antibodies on tau protein and relationship with Alzheimer tau.
    Lichtenberg-Kraag B; Mandelkow EM; Biernat J; Steiner B; Schröter C; Gustke N; Meyer HE; Mandelkow E
    Proc Natl Acad Sci U S A; 1992 Jun; 89(12):5384-8. PubMed ID: 1376918
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Brain proline-directed protein kinase phosphorylates tau on sites that are abnormally phosphorylated in tau associated with Alzheimer's paired helical filaments.
    Paudel HK; Lew J; Ali Z; Wang JH
    J Biol Chem; 1993 Nov; 268(31):23512-8. PubMed ID: 8226879
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The switch of tau protein to an Alzheimer-like state includes the phosphorylation of two serine-proline motifs upstream of the microtubule binding region.
    Biernat J; Mandelkow EM; Schröter C; Lichtenberg-Kraag B; Steiner B; Berling B; Meyer H; Mercken M; Vandermeeren A; Goedert M; Mandelkow E
    EMBO J; 1992 Apr; 11(4):1593-7. PubMed ID: 1563356
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Implication of brain cdc2 and MAP2 kinases in the phosphorylation of tau protein in Alzheimer's disease.
    Ledesma MD; Correas I; Avila J; Díaz-Nido J
    FEBS Lett; 1992 Aug; 308(2):218-24. PubMed ID: 1323485
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Microtubule-associated protein/microtubule affinity-regulating kinase (p110mark). A novel protein kinase that regulates tau-microtubule interactions and dynamic instability by phosphorylation at the Alzheimer-specific site serine 262.
    Drewes G; Trinczek B; Illenberger S; Biernat J; Schmitt-Ulms G; Meyer HE; Mandelkow EM; Mandelkow E
    J Biol Chem; 1995 Mar; 270(13):7679-88. PubMed ID: 7706316
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Phosphorylation of Ser262 strongly reduces binding of tau to microtubules: distinction between PHF-like immunoreactivity and microtubule binding.
    Biernat J; Gustke N; Drewes G; Mandelkow EM; Mandelkow E
    Neuron; 1993 Jul; 11(1):153-63. PubMed ID: 8393323
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Comparison of the phosphorylation of microtubule-associated protein tau by non-proline dependent protein kinases.
    Singh TJ; Grundke-Iqbal I; McDonald B; Iqbal K
    Mol Cell Biochem; 1994 Feb; 131(2):181-9. PubMed ID: 8035784
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Protein kinase FA/glycogen synthase kinase-3 alpha after heparin potentiation phosphorylates tau on sites abnormally phosphorylated in Alzheimer's disease brain.
    Yang SD; Yu JS; Shiah SG; Huang JJ
    J Neurochem; 1994 Oct; 63(4):1416-25. PubMed ID: 7931292
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Microtubule-associated protein tau, paired helical filaments, and phosphorylation.
    Mandelkow EM; Biernat J; Drewes G; Steiner B; Lichtenberg-Kraag B; Wille H; Gustke N; Mandelkow E
    Ann N Y Acad Sci; 1993 Sep; 695():209-16. PubMed ID: 7694533
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Sites of phosphorylation in tau and factors affecting their regulation.
    Anderton BH; Betts J; Blackstock WP; Brion JP; Chapman S; Connell J; Dayanandan R; Gallo JM; Gibb G; Hanger DP; Hutton M; Kardalinou E; Leroy K; Lovestone S; Mack T; Reynolds CH; Van Slegtenhorst M
    Biochem Soc Symp; 2001; (67):73-80. PubMed ID: 11447841
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Sequential phosphorylation of Tau by glycogen synthase kinase-3beta and protein kinase A at Thr212 and Ser214 generates the Alzheimer-specific epitope of antibody AT100 and requires a paired-helical-filament-like conformation.
    Zheng-Fischhöfer Q; Biernat J; Mandelkow EM; Illenberger S; Godemann R; Mandelkow E
    Eur J Biochem; 1998 Mar; 252(3):542-52. PubMed ID: 9546672
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Glycogen synthase kinase-3 induces Alzheimer's disease-like phosphorylation of tau: generation of paired helical filament epitopes and neuronal localisation of the kinase.
    Hanger DP; Hughes K; Woodgett JR; Brion JP; Anderton BH
    Neurosci Lett; 1992 Nov; 147(1):58-62. PubMed ID: 1336152
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Phosphorylation that detaches tau protein from microtubules (Ser262, Ser214) also protects it against aggregation into Alzheimer paired helical filaments.
    Schneider A; Biernat J; von Bergen M; Mandelkow E; Mandelkow EM
    Biochemistry; 1999 Mar; 38(12):3549-58. PubMed ID: 10090741
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The Alzheimer-like phosphorylation of tau protein reduces microtubule binding and involves Ser-Pro and Thr-Pro motifs.
    Gustke N; Steiner B; Mandelkow EM; Biernat J; Meyer HE; Goedert M; Mandelkow E
    FEBS Lett; 1992 Jul; 307(2):199-205. PubMed ID: 1644173
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 16.