162 related articles for article (PubMed ID: 1379586)
1. Monoclonal antibodies recognizing protease-generated neoepitopes from cartilage proteoglycan degradation. Application to studies of human link protein cleavage by stromelysin.
Hughes CE; Caterson B; White RJ; Roughley PJ; Mort JS
J Biol Chem; 1992 Aug; 267(23):16011-4. PubMed ID: 1379586
[TBL] [Abstract][Full Text] [Related]
2. Monoclonal antibodies that specifically recognize neoepitope sequences generated by 'aggrecanase' and matrix metalloproteinase cleavage of aggrecan: application to catabolism in situ and in vitro.
Hughes CE; Caterson B; Fosang AJ; Roughley PJ; Mort JS
Biochem J; 1995 Feb; 305 ( Pt 3)(Pt 3):799-804. PubMed ID: 7531436
[TBL] [Abstract][Full Text] [Related]
3. Use of an antibody against the matrix metalloproteinase-generated aggrecan neoepitope FVDIPEN-COOH to assess the effects of stromelysin in a rabbit model of cartilage degradation.
Bayne EK; MacNaul KL; Donatelli SA; Christen A; Griffin PR; Hoerrner LA; Calaycay JR; Ayala JM; Chapman K; Hagmann W
Arthritis Rheum; 1995 Oct; 38(10):1400-9. PubMed ID: 7575690
[TBL] [Abstract][Full Text] [Related]
4. Degradation of proteoglycan aggregate by a cartilage metalloproteinase. Evidence for the involvement of stromelysin in the generation of link protein heterogeneity in situ.
Nguyen Q; Murphy G; Roughley PJ; Mort JS
Biochem J; 1989 Apr; 259(1):61-7. PubMed ID: 2719651
[TBL] [Abstract][Full Text] [Related]
5. Link protein as a monitor in situ of endogenous proteolysis in adult human articular cartilage.
Nguyen Q; Liu J; Roughley PJ; Mort JS
Biochem J; 1991 Aug; 278 ( Pt 1)(Pt 1):143-7. PubMed ID: 1883326
[TBL] [Abstract][Full Text] [Related]
6. Matrix metalloproteinases cleave at two distinct sites on human cartilage link protein.
Nguyen Q; Murphy G; Hughes CE; Mort JS; Roughley PJ
Biochem J; 1993 Oct; 295 ( Pt 2)(Pt 2):595-8. PubMed ID: 7694569
[TBL] [Abstract][Full Text] [Related]
7. A stromelysin assay for the assessment of metalloprotease inhibitors on human aggregated proteoglycan.
Doughty JR; Goldberg RL; Ganu V; Melton RA; Hu SI; Di Pasquale G
Agents Actions; 1993; 39 Spec No():C151-3. PubMed ID: 7506000
[TBL] [Abstract][Full Text] [Related]
8. Development of a cleavage-site-specific monoclonal antibody for detecting metalloproteinase-derived aggrecan fragments: detection of fragments in human synovial fluids.
Fosang AJ; Last K; Gardiner P; Jackson DC; Brown L
Biochem J; 1995 Aug; 310 ( Pt 1)(Pt 1):337-43. PubMed ID: 7544117
[TBL] [Abstract][Full Text] [Related]
9. Monoclonal antibodies as probes for determining the microheterogeneity of the link proteins of cartilage proteoglycan.
Caterson B; Baker JR; Christner JE; Lee Y; Lentz M
J Biol Chem; 1985 Sep; 260(20):11348-56. PubMed ID: 2411733
[TBL] [Abstract][Full Text] [Related]
10. Aggrecan degradation in human intervertebral disc and articular cartilage.
Sztrolovics R; Alini M; Roughley PJ; Mort JS
Biochem J; 1997 Aug; 326 ( Pt 1)(Pt 1):235-41. PubMed ID: 9337874
[TBL] [Abstract][Full Text] [Related]
11. Aggrecan degradation in human cartilage. Evidence for both matrix metalloproteinase and aggrecanase activity in normal, osteoarthritic, and rheumatoid joints.
Lark MW; Bayne EK; Flanagan J; Harper CF; Hoerrner LA; Hutchinson NI; Singer II; Donatelli SA; Weidner JR; Williams HR; Mumford RA; Lohmander LS
J Clin Invest; 1997 Jul; 100(1):93-106. PubMed ID: 9202061
[TBL] [Abstract][Full Text] [Related]
12. Link protein shows species variation in its susceptibility to proteolysis.
Liu J; Cassidy JD; Allan A; Neame PJ; Mort JS; Roughley PJ
J Orthop Res; 1992 Sep; 10(5):621-30. PubMed ID: 1500976
[TBL] [Abstract][Full Text] [Related]
13. Cleavage of cartilage proteoglycan between G1 and G2 domains by stromelysins.
Fosang AJ; Neame PJ; Hardingham TE; Murphy G; Hamilton JA
J Biol Chem; 1991 Aug; 266(24):15579-82. PubMed ID: 1874716
[TBL] [Abstract][Full Text] [Related]
14. Development of enzyme immunoassays specific for keratan sulphate- and core-protein-epitopes of the large aggregating proteoglycan from human articular cartilage.
Fischer DC; Kolbe-Busch S; Stöcker G; Hoffmann A; Haubeck HD
Eur J Clin Chem Clin Biochem; 1994 Apr; 32(4):285-91. PubMed ID: 7518698
[TBL] [Abstract][Full Text] [Related]
15. VDIPEN, a metalloproteinase-generated neoepitope, is induced and immunolocalized in articular cartilage during inflammatory arthritis.
Singer II; Kawka DW; Bayne EK; Donatelli SA; Weidner JR; Williams HR; Ayala JM; Mumford RA; Lark MW; Glant TT
J Clin Invest; 1995 May; 95(5):2178-86. PubMed ID: 7537757
[TBL] [Abstract][Full Text] [Related]
16. Normal human synovial fluid and articular cartilage contain similar intact proteoglycans.
Heimer R; Sporer R; Molinaro L; Hansen L; Laposata E
Lab Invest; 1992 Jun; 66(6):701-7. PubMed ID: 1376375
[TBL] [Abstract][Full Text] [Related]
17. Cleavage of aggrecan at the Asn341-Phe342 site coincides with the initiation of collagen damage in murine antigen-induced arthritis: a pivotal role for stromelysin 1 in matrix metalloproteinase activity.
van Meurs J; van Lent P; Stoop R; Holthuysen A; Singer I; Bayne E; Mudgett J; Poole R; Billinghurst C; van der Kraan P; Buma P; van den Berg W
Arthritis Rheum; 1999 Oct; 42(10):2074-84. PubMed ID: 10524678
[TBL] [Abstract][Full Text] [Related]
18. Quantification of a matrix metalloproteinase-generated aggrecan G1 fragment using monospecific anti-peptide serum.
Lark MW; Williams H; Hoernner LA; Weidner J; Ayala JM; Harper CF; Christen A; Olszewski J; Konteatis Z; Webber R
Biochem J; 1995 Apr; 307 ( Pt 1)(Pt 1):245-52. PubMed ID: 7717983
[TBL] [Abstract][Full Text] [Related]
19. Monoclonal antibodies against human collagenase and stromelysin.
Su JL; Becherer JD; Edwards C; Bukhart W; McGeehan GM; Champion BR
Hybridoma; 1995 Aug; 14(4):383-90. PubMed ID: 8522351
[TBL] [Abstract][Full Text] [Related]
20. Sensitivity of monoclonal antibody, 5-D-4, for the detection of aggrecan, aggrecan fragments, and keratan sulfate.
Saphos CA; Dey P; Lark MW; Moore VL
Agents Actions; 1993; 39 Spec No():C154-6. PubMed ID: 7506001
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]