BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

141 related articles for article (PubMed ID: 1381235)

  • 1. Defective transport as a mechanism of acquired resistance to methotrexate in patients with acute lymphocytic leukemia.
    Trippett T; Schlemmer S; Elisseyeff Y; Goker E; Wachter M; Steinherz P; Tan C; Berman E; Wright JE; Rosowsky A
    Blood; 1992 Sep; 80(5):1158-62. PubMed ID: 1381235
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Defective transport is a common mechanism of acquired methotrexate resistance in acute lymphocytic leukemia and is associated with decreased reduced folate carrier expression.
    Gorlick R; Goker E; Trippett T; Steinherz P; Elisseyeff Y; Mazumdar M; Flintoff WF; Bertino JR
    Blood; 1997 Feb; 89(3):1013-8. PubMed ID: 9028333
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Cytotoxicity of trimetrexate against antifolate-resistant human T-cell leukemia cell lines developed in oxidized or reduced folate.
    Miyachi H; Takemura Y; Kobayashi H; Ando Y
    Jpn J Cancer Res; 1997 Sep; 88(9):900-6. PubMed ID: 9369939
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Selective treatment of SCID mice bearing methotrexate-transport-resistant human acute lymphoblastic leukemia tumors with trimetrexate and leucovorin protection.
    Lacerda JF; Göker E; Kheradpour A; Dennig D; Elisseyeff Y; Jagiello C; O'Reilly RJ; Bertino JR
    Blood; 1995 May; 85(10):2675-9. PubMed ID: 7742525
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Identification of a membrane-associated folate-binding protein in human leukemic CCRF-CEM cells with transport-related methotrexate resistance.
    Jansen G; Westerhof GR; Kathmann I; Rademaker BC; Rijksen G; Schornagel JH
    Cancer Res; 1989 May; 49(9):2455-9. PubMed ID: 2706633
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Elevated dihydrofolate reductase and impaired methotrexate transport as elements in methotrexate resistance in childhood acute lymphoblastic leukemia.
    Matherly LH; Taub JW; Ravindranath Y; Proefke SA; Wong SC; Gimotty P; Buck S; Wright JE; Rosowsky A
    Blood; 1995 Jan; 85(2):500-9. PubMed ID: 7812005
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Basis for natural resistance to methotrexate in human acute non-lymphocytic leukemia.
    Lin JT; Tong WP; Trippett TM; Niedzwiecki D; Tao Y; Tan C; Steinherz P; Schweitzer BI; Bertino JR
    Leuk Res; 1991; 15(12):1191-6. PubMed ID: 1722550
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Multiple mechanisms of resistance to methotrexate and novel antifolates in human CCRF-CEM leukemia cells and their implications for folate homeostasis.
    Mauritz R; Peters GJ; Priest DG; Assaraf YG; Drori S; Kathmann I; Noordhuis P; Bunni MA; Rosowsky A; Schornagel JH; Pinedo HM; Jansen G
    Biochem Pharmacol; 2002 Jan; 63(2):105-15. PubMed ID: 11841783
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Differential methotrexate resistance in childhood T- versus common/preB-acute lymphoblastic leukemia can be measured by an in situ thymidylate synthase inhibition assay, but not by the MTT assay.
    Rots MG; Pieters R; Kaspers GJ; van Zantwijk CH; Noordhuis P; Mauritz R; Veerman AJ; Jansen G; Peters GJ
    Blood; 1999 Feb; 93(3):1067-74. PubMed ID: 9920857
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Blast cell methotrexate-polyglutamate accumulation in vivo differs by lineage, ploidy, and methotrexate dose in acute lymphoblastic leukemia.
    Synold TW; Relling MV; Boyett JM; Rivera GK; Sandlund JT; Mahmoud H; Crist WM; Pui CH; Evans WE
    J Clin Invest; 1994 Nov; 94(5):1996-2001. PubMed ID: 7525652
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Ex vivo resistance in childhood acute lymphoblastic leukemia: Correlations between BCRP, MRP1, MRP4 and MRP5 ABC transporter expression and intracellular methotrexate polyglutamate accumulation.
    Jaramillo AC; Cloos J; Lemos C; Stam RW; Kaspers GJL; Jansen G; Peters GJ
    Leuk Res; 2019 Apr; 79():45-51. PubMed ID: 30849662
    [TBL] [Abstract][Full Text] [Related]  

  • 12. 5-amino-4-imidazolecarboxamide riboside potentiates both transport of reduced folates and antifolates by the human reduced folate carrier and their subsequent metabolism.
    McGuire JJ; Haile WH; Yeh CC
    Cancer Res; 2006 Apr; 66(7):3836-44. PubMed ID: 16585211
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Patterns of cross-resistance to the antifolate drugs trimetrexate, metoprine, homofolate, and CB3717 in human lymphoma and osteosarcoma cells resistant to methotrexate.
    Diddens H; Niethammer D; Jackson RC
    Cancer Res; 1983 Nov; 43(11):5286-92. PubMed ID: 6225514
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Mechanisms of methotrexate resistance in acute leukemia. Decreased transport and polyglutamylation.
    Gorlick R; Cole P; Banerjee D; Longo G; Li WW; Hochhauser D; Bertino JR
    Adv Exp Med Biol; 1999; 457():543-50. PubMed ID: 10500832
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Acute monocytic leukemia: a myeloid leukemia subset that may be sensitive to methotrexate.
    Göker E; Kheradpour A; Waltham M; Banerjee D; Tong WP; Elisseyeff Y; Bertino JR
    Leukemia; 1995 Feb; 9(2):274-6. PubMed ID: 7532768
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Reduced folate carrier expression in acute lymphoblastic leukemia: a mechanism for ploidy but not lineage differences in methotrexate accumulation.
    Belkov VM; Krynetski EY; Schuetz JD; Yanishevski Y; Masson E; Mathew S; Raimondi S; Pui CH; Relling MV; Evans WE
    Blood; 1999 Mar; 93(5):1643-50. PubMed ID: 10029593
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Regulation of carrier-mediated transport of folates and antifolates in methotrexate-sensitive and-resistant leukemia cells.
    Jansen G; Mauritz RM; Assaraf YG; Sprecher H; Drori S; Kathmann I; Westerhof GR; Priest DG; Bunni M; Pinedo HM; Schornagel JH; Peters GJ
    Adv Enzyme Regul; 1997; 37():59-76. PubMed ID: 9381986
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Decreased polyglutamylation of methotrexate in acute lymphoblastic leukemia blasts in adults compared to children with this disease.
    Göker E; Lin JT; Trippett T; Elisseyeff Y; Tong WP; Niedzwiecki D; Tan C; Steinherz P; Schweitzer BI; Bertino JR
    Leukemia; 1993 Jul; 7(7):1000-4. PubMed ID: 7686600
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Methotrexate resistance in relation to treatment outcome in childhood acute lymphoblastic leukemia.
    Wojtuszkiewicz A; Peters GJ; van Woerden NL; Dubbelman B; Escherich G; Schmiegelow K; Sonneveld E; Pieters R; van de Ven PM; Jansen G; Assaraf YG; Kaspers GJ; Cloos J
    J Hematol Oncol; 2015 May; 8():61. PubMed ID: 26022503
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Accumulation of methotrexate polyglutamates in lymphoblasts is a determinant of antileukemic effects in vivo. A rationale for high-dose methotrexate.
    Masson E; Relling MV; Synold TW; Liu Q; Schuetz JD; Sandlund JT; Pui CH; Evans WE
    J Clin Invest; 1996 Jan; 97(1):73-80. PubMed ID: 8550853
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.