BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

137 related articles for article (PubMed ID: 1394130)

  • 1. Epigenetic silencing of the DNA repair enzyme O6-methylguanine-DNA methyltransferase in Mex- human cells.
    Cairns-Smith S; Karran P
    Cancer Res; 1992 Oct; 52(19):5257-63. PubMed ID: 1394130
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Cytosine methylation and suppression of O6-methylguanine-DNA methyltransferase expression in human rhabdomyosarcoma cell lines and xenografts.
    von Wronski MA; Harris LC; Tano K; Mitra S; Bigner DD; Brent TP
    Oncol Res; 1992; 4(4-5):167-74. PubMed ID: 1504376
    [TBL] [Abstract][Full Text] [Related]  

  • 3. CpG methylation-dependent repression of the human O6-methylguanine-DNA methyltransferase gene linked to chromatin structure alteration.
    Bhakat KK; Mitra S
    Carcinogenesis; 2003 Aug; 24(8):1337-45. PubMed ID: 12807730
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Influence of CpG island methylation status in O6-methylguanine-DNA methyltransferase expression of oral cancer cell lines.
    Murakami J; Asaumi J; Maki Y; Tsujigiwa H; Nagatsuka H; Kokeguchi S; Inoue T; Kawasaki S; Tanaka N; MacPhee D; Matsubara N; Kishi K
    Oncol Rep; 2004 Aug; 12(2):339-45. PubMed ID: 15254699
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Induction of c-fos, c-jun, junB and junD mRNA and AP-1 by alkylating mutagens in cells deficient and proficient for the DNA repair protein O6-methylguanine-DNA methyltransferase (MGMT) and its relationship to cell death, mutation induction and chromosomal instability.
    Dosch J; Kaina B
    Oncogene; 1996 Nov; 13(9):1927-35. PubMed ID: 8934539
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Alterations in S-adenosylhomocysteine metabolism decrease O6-methylguanine DNA methyltransferase gene expression without affecting promoter methylation.
    Hermes M; Geisler H; Osswald H; Riehle R; Kloor D
    Biochem Pharmacol; 2008 Jun; 75(11):2100-11. PubMed ID: 18395186
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Methylation hot spots in the 5' flanking region denote silencing of the O6-methylguanine-DNA methyltransferase gene.
    Qian XC; Brent TP
    Cancer Res; 1997 Sep; 57(17):3672-7. PubMed ID: 9288770
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Inactivation of the DNA repair gene O6-methylguanine-DNA methyltransferase by promoter hypermethylation is a common event in primary human neoplasia.
    Esteller M; Hamilton SR; Burger PC; Baylin SB; Herman JG
    Cancer Res; 1999 Feb; 59(4):793-7. PubMed ID: 10029064
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Coregulation of the human O6-methylguanine-DNA methyltransferase with two unrelated genes that are closely linked.
    Karran P; Stephenson C; Macpherson P; Cairns-Smith S; Priestley A
    Cancer Res; 1990 Mar; 50(5):1532-7. PubMed ID: 2137369
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Epigenetic silencing of O6-methylguanine DNA methyltransferase gene in NiS-transformed cells.
    Ji W; Yang L; Yu L; Yuan J; Hu D; Zhang W; Yang J; Pang Y; Li W; Lu J; Fu J; Chen J; Lin Z; Chen W; Zhuang Z
    Carcinogenesis; 2008 Jun; 29(6):1267-75. PubMed ID: 18204074
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Promoter hypermethylation of the DNA repair gene O(6)-methylguanine-DNA methyltransferase is associated with the presence of G:C to A:T transition mutations in p53 in human colorectal tumorigenesis.
    Esteller M; Risques RA; Toyota M; Capella G; Moreno V; Peinado MA; Baylin SB; Herman JG
    Cancer Res; 2001 Jun; 61(12):4689-92. PubMed ID: 11406538
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Inhibition of human O6-methylguanine-DNA methyltransferase by 5-methylcytosine.
    Bentivegna SS; Bresnick E
    Cancer Res; 1994 Jan; 54(2):327-9. PubMed ID: 8275462
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Silencing effect of CpG island hypermethylation and histone modifications on O6-methylguanine-DNA methyltransferase (MGMT) gene expression in human cancer.
    Nakagawachi T; Soejima H; Urano T; Zhao W; Higashimoto K; Satoh Y; Matsukura S; Kudo S; Kitajima Y; Harada H; Furukawa K; Matsuzaki H; Emi M; Nakabeppu Y; Miyazaki K; Sekiguchi M; Mukai T
    Oncogene; 2003 Dec; 22(55):8835-44. PubMed ID: 14647440
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Inactivation of the DNA repair gene O6-methylguanine-DNA methyltransferase by promoter hypermethylation is associated with G to A mutations in K-ras in colorectal tumorigenesis.
    Esteller M; Toyota M; Sanchez-Cespedes M; Capella G; Peinado MA; Watkins DN; Issa JP; Sidransky D; Baylin SB; Herman JG
    Cancer Res; 2000 May; 60(9):2368-71. PubMed ID: 10811111
    [TBL] [Abstract][Full Text] [Related]  

  • 15. A comparison of human O6-methylguanine-DNA methyltransferase promoter activity in Mer+ and Mer- cells.
    Harris LC; Potter PM; Remack JS; Brent TP
    Cancer Res; 1992 Nov; 52(22):6404-6. PubMed ID: 1423289
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Expression of human O6-methylguanine-DNA methyltransferase in a DNA excision repair-deficient Chinese hamster ovary cell line and its response to certain alkylating agents.
    Wu ZN; Chan CL; Eastman A; Bresnick E
    Cancer Res; 1992 Jan; 52(1):32-5. PubMed ID: 1727384
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Methylation of selected CpGs in the human O6-methylguanine-DNA methyltransferase promoter region as a marker of gene silencing.
    Danam RP; Qian XC; Howell SR; Brent TP
    Mol Carcinog; 1999 Feb; 24(2):85-9. PubMed ID: 10078935
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Ribozyme-mediated modulation of human O6-methylguanine-DNA methyltransferase expression.
    Potter PM; Harris LC; Remack JS; Edwards CC; Brent TP
    Cancer Res; 1993 Apr; 53(8):1731-4. PubMed ID: 8467487
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Epigenetic regulation of the MGMT and hMSH6 DNA repair genes in cells resistant to methylating agents.
    Bearzatto A; Szadkowski M; Macpherson P; Jiricny J; Karran P
    Cancer Res; 2000 Jun; 60(12):3262-70. PubMed ID: 10866320
    [TBL] [Abstract][Full Text] [Related]  

  • 20. O6-methylguanine-DNA methyltransferase regulation by p53 in astrocytic cells.
    Blough MD; Zlatescu MC; Cairncross JG
    Cancer Res; 2007 Jan; 67(2):580-4. PubMed ID: 17234766
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.