BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

102 related articles for article (PubMed ID: 1420442)

  • 1. Influence of a peptide linker on biodistribution and metabolism of antibody-conjugated benzyl-EDTA. Comparison of enzymatic digestion in vitro and in vivo.
    Studer M; Kroger LA; DeNardo SJ; Kukis DL; Meares CF
    Bioconjug Chem; 1992; 3(5):424-9. PubMed ID: 1420442
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Metabolism of indium chelates attached to monoclonal antibody: minimal transchelation of indium from benzyl-EDTA chelate in vivo.
    Deshpande SV; Subramanian R; McCall MJ; DeNardo SJ; DeNardo GL; Meares CF
    J Nucl Med; 1990 Feb; 31(2):218-24. PubMed ID: 2107283
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Stability of a metabolizable ester bond in radioimmunoconjugates.
    Arano Y; Wakisaka K; Mukai T; Uezono T; Motonari H; Akizawa H; Kairiyama C; Ohmomo Y; Tanaka C; Ishiyama M; Sakahara H; Konishi J; Yokoyama A
    Nucl Med Biol; 1996 Feb; 23(2):129-36. PubMed ID: 8868284
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Radiolabeled metabolites of proteins play a critical role in radioactivity elimination from the liver.
    Arano Y; Mukai T; Akizawa H; Uezono T; Motonari H; Wakisaka K; Kairiyama C; Yokoyama A
    Nucl Med Biol; 1995 Jul; 22(5):555-64. PubMed ID: 7581163
    [TBL] [Abstract][Full Text] [Related]  

  • 5. [Comparative studies of 111In-labeled monoclonal antibody using spacer-containing and non-spacer bifunctional chelates: (II). Biodistribution, metabolism and excretion in vivo].
    Sun B
    Kaku Igaku; 1994 May; 31(5):473-87. PubMed ID: 8028219
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Albumin-binding prodrugs of camptothecin and doxorubicin with an Ala-Leu-Ala-Leu-linker that are cleaved by cathepsin B: synthesis and antitumor efficacy.
    Schmid B; Chung DE; Warnecke A; Fichtner I; Kratz F
    Bioconjug Chem; 2007; 18(3):702-16. PubMed ID: 17378599
    [TBL] [Abstract][Full Text] [Related]  

  • 7. [p-Nitroanilides of amino acids and peptides and fluorescence peptide with inner fluorescence quenching as substrates for cathepsins H, B, D and high molecular weight aspartic peptidase in the brain].
    Azarian AV; Agatian GL; Galoian AA
    Biokhimiia; 1987 Dec; 52(12):2033-7. PubMed ID: 3328984
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Structural features of the antibody-A chain linkage that influence the activity and stability of ricin A chain immunotoxins.
    Cumber AJ; Westwood JH; Henry RV; Parnell GD; Coles BF; Wawrzynczak EJ
    Bioconjug Chem; 1992; 3(5):397-401. PubMed ID: 1329989
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Introduction of five potentially metabolizable linking groups between 111In-cyclohexyl EDTA derivatives and F(ab')2 fragments of anti-carcinoembryonic antigen antibody--I. A new reproducible synthetic method.
    Gestin JF; Faivre-Chauvet A; Mease RC; Sai-Maurel C; Thédrez P; Slinkin M; Meinken GE; Srivastava SC; Chatal JF
    Nucl Med Biol; 1993 Aug; 20(6):755-62. PubMed ID: 8401376
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Effect of mass of 111In-benzyl-EDTA monoclonal antibody on hepatic uptake and processing in mice.
    Adams GP; DeNardo SJ; Deshpande SV; DeNardo GL; Meares CF; McCall MJ; Epstein AL
    Cancer Res; 1989 Apr; 49(7):1707-11. PubMed ID: 2493983
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Effect of the extent of chelate substitution on the immunoreactivity and biodistribution of 2IT-BAT-Lym-1 immunoconjugates.
    Kukis DL; DeNardo GL; DeNardo SJ; Mirick GR; Miers LA; Greiner DP; Meares CF
    Cancer Res; 1995 Feb; 55(4):878-84. PubMed ID: 7850803
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Introduction of five potentially metabolizable linking groups between 111In-cyclohexyl EDTA derivatives and F(ab')2 fragments of anti-carcinoembryonic antigen antibody--II. Comparative pharmacokinetics and biodistribution in human colorectal carcinoma-bearing nude mice.
    Faivre-Chauvet A; Gestin JF; Mease RC; Sai-Maurel C; Thédrez P; Slinkin M; Meinken GE; Srivastava SC; Chatal JF
    Nucl Med Biol; 1993 Aug; 20(6):763-71. PubMed ID: 8401377
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Effect of different linkages between chelates and monoclonal antibodies on levels of radioactivity in the liver.
    Deshpande SV; Denardo SJ; Meares CF; McCall MJ; Adams GP; Denardo GL
    Int J Rad Appl Instrum B; 1989; 16(6):587-97. PubMed ID: 2606714
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Assessment of radiochemical design of antibodies using an ester bond as the metabolizable linkage: evaluation of maleimidoethyl 3-(tri-n-butylstannyl)hippurate as a radioiodination reagent of antibodies for diagnostic and therapeutic applications.
    Arano Y; Wakisaka K; Ohmono Y; Uezono T; Akizawa H; Nakayama M; Sakahara H; Tanaka C; Konishi J; Yokoyama A
    Bioconjug Chem; 1996; 7(6):628-37. PubMed ID: 8950481
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Processing of antibody-radioisotope conjugates after binding to the surface of tumor cells.
    Mattes MJ; Griffiths GL; Diril H; Goldenberg DM; Ong GL; Shih LB
    Cancer; 1994 Feb; 73(3 Suppl):787-93. PubMed ID: 8306261
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Assessment of the radiochemical design of antibodies with a metabolizable linkage for target-selective radioactivity delivery.
    Arano Y; Wakisaka K; Akizawa H; Ono M; Kawai K; Nakayama M; Sakahara H; Konishi J; Saji H
    Bioconjug Chem; 1998; 9(4):497-506. PubMed ID: 9667952
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Effect of metabolism on retention of indium-111-labeled monoclonal antibody in liver and blood.
    Kinuya S; Jeong JM; Garmestani K; Saga T; Camera L; Brechbiel MW; Gansow OA; Carrasquillo JA; Neumann RD; Paik CH
    J Nucl Med; 1994 Nov; 35(11):1851-7. PubMed ID: 7965168
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Metal decomposition rates of 111In-DTPA and EDTA conjugates of monoclonal antibodies in vivo.
    Goodwin DA; Meares CF; McTigue M; McCall MJ; Chaovapong W
    Nucl Med Commun; 1986 Nov; 7(11):831-8. PubMed ID: 3106867
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Structure-function relationships in indium-111 radioimmunoconjugates.
    Brandt KD; Johnson DK
    Bioconjug Chem; 1992; 3(2):118-25. PubMed ID: 1515465
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Influence of the linker on the biodistribution and catabolism of actinium-225 self-immolative tumor-targeted isotope generators.
    Antczak C; Jaggi JS; LeFave CV; Curcio MJ; McDevitt MR; Scheinberg DA
    Bioconjug Chem; 2006; 17(6):1551-60. PubMed ID: 17105236
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.