BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

434 related articles for article (PubMed ID: 1428403)

  • 1. Engineering a humanized bispecific F(ab')2 fragment for improved binding to T cells.
    Rodrigues ML; Shalaby MR; Werther W; Presta L; Carter P
    Int J Cancer Suppl; 1992; 7():45-50. PubMed ID: 1428403
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Identification of heavy chain residues in a humanized anti-CD3 antibody important for efficient antigen binding and T cell activation.
    Zhu Z; Carter P
    J Immunol; 1995 Aug; 155(4):1903-10. PubMed ID: 7636241
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Engineering Fab' fragments for efficient F(ab)2 formation in Escherichia coli and for improved in vivo stability.
    Rodrigues ML; Snedecor B; Chen C; Wong WL; Garg S; Blank GS; Maneval D; Carter P
    J Immunol; 1993 Dec; 151(12):6954-61. PubMed ID: 7903100
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Trispecific F(ab')3 derivatives that use cooperative signaling via the TCR/CD3 complex and CD2 to activate and redirect resting cytotoxic T cells.
    Tutt A; Stevenson GT; Glennie MJ
    J Immunol; 1991 Jul; 147(1):60-9. PubMed ID: 1675655
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Engineering high affinity humanized anti-p185HER2/anti-CD3 bispecific F(ab')2 for efficient lysis of p185HER2 overexpressing tumor cells.
    Zhu Z; Lewis GD; Carter P
    Int J Cancer; 1995 Jul; 62(3):319-24. PubMed ID: 7628874
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The role of T cell activation in anti-CD3 x antitumor bispecific antibody therapy.
    Weiner GJ; Kostelny SA; Hillstrom JR; Cole MS; Link BK; Wang SL; Tso JY
    J Immunol; 1994 Mar; 152(5):2385-92. PubMed ID: 8133049
    [TBL] [Abstract][Full Text] [Related]  

  • 7. [High level expression of chimeric antibody fragment F(ab')2 directed against CD20 in Escherichia coli].
    Xiong DS; Zheng MJ; Liu YX; Xu YF; Wang JH; Yang CZ
    Sheng Wu Gong Cheng Xue Bao; 2004 Sep; 20(5):673-8. PubMed ID: 15973988
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Functional humanization of an anti-CD16 Fab fragment: obstacles of switching from murine {lambda} to human {lambda} or {kappa} light chains.
    Schlapschy M; Fogarasi M; Gruber H; Gresch O; Schäfer C; Aguib Y; Skerra A
    Protein Eng Des Sel; 2009 Mar; 22(3):175-88. PubMed ID: 19022801
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Valency of CD3 binding and internalization of the CD3 cell-surface complex control T cell responses to second signals: distinction between effects on protein kinase C, cytoplasmic free calcium, and proliferation.
    Ledbetter JA; June CH; Martin PJ; Spooner CE; Hansen JA; Meier KE
    J Immunol; 1986 Jun; 136(11):3945-52. PubMed ID: 3084650
    [TBL] [Abstract][Full Text] [Related]  

  • 10. An anti-murine CD3 monoclonal antibody with a low affinity for Fc gamma receptors suppresses transplantation responses while minimizing acute toxicity and immunogenicity.
    Alegre ML; Tso JY; Sattar HA; Smith J; Desalle F; Cole M; Bluestone JA
    J Immunol; 1995 Aug; 155(3):1544-55. PubMed ID: 7636216
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Development of humanized bispecific antibodies reactive with cytotoxic lymphocytes and tumor cells overexpressing the HER2 protooncogene.
    Shalaby MR; Shepard HM; Presta L; Rodrigues ML; Beverley PC; Feldmann M; Carter P
    J Exp Med; 1992 Jan; 175(1):217-25. PubMed ID: 1346155
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Anti-CD3 x anti-tumor F(ab')2 bifunctional antibody activates and retargets tumor-infiltrating lymphocytes.
    Chapoval AI; Nelson H; Thibault C
    J Immunol; 1995 Aug; 155(3):1296-303. PubMed ID: 7636196
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Formation of a bispecific antibody by the use of leucine zippers.
    Kostelny SA; Cole MS; Tso JY
    J Immunol; 1992 Mar; 148(5):1547-53. PubMed ID: 1531669
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Differential T cell hyporesponsiveness induced by in vivo administration of intact or F(ab')2 fragments of anti-CD3 monoclonal antibody. F(ab')2 fragments induce a selective T helper dysfunction.
    Hirsch R; Archibald J; Gress RE
    J Immunol; 1991 Oct; 147(7):2088-93. PubMed ID: 1833451
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Bispecific F (ab')2 monomer prepared with anti-CD3 and anti-tumor monoclonal antibodies is most potent in induction of cytolysis of human T cells.
    Nitta T; Yagita H; Azuma T; Sato K; Okumura K
    Eur J Immunol; 1989 Aug; 19(8):1437-41. PubMed ID: 2528460
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Humanized OKT3 antibodies: successful transfer of immune modulating properties and idiotype expression.
    Woodle ES; Thistlethwaite JR; Jolliffe LK; Zivin RA; Collins A; Adair JR; Bodmer M; Athwal D; Alegre ML; Bluestone JA
    J Immunol; 1992 May; 148(9):2756-63. PubMed ID: 1533410
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Functional humanization of an anti-CD30 Fab fragment for the immunotherapy of Hodgkin's lymphoma using an in vitro evolution approach.
    Schlapschy M; Gruber H; Gresch O; Schäfer C; Renner C; Pfreundschuh M; Skerra A
    Protein Eng Des Sel; 2004 Dec; 17(12):847-60. PubMed ID: 15708864
    [TBL] [Abstract][Full Text] [Related]  

  • 18. CD3 directed bispecific antibodies induce increased lymphocyte-endothelial cell interactions in vitro.
    Molema G; Tervaert JW; Kroesen BJ; Helfrich W; Meijer DK; de Leij LF
    Br J Cancer; 2000 Jan; 82(2):472-9. PubMed ID: 10646907
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Comparison of the three-dimensional structures of a humanized and a chimeric Fab of an anti-gamma-interferon antibody.
    Fan ZC; Shan L; Goldsteen BZ; Guddat LW; Thakur A; Landolfi NF; Co MS; Vasquez M; Queen C; Ramsland PA; Edmundson AB
    J Mol Recognit; 1999; 12(1):19-32. PubMed ID: 10398393
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Humanization of the murine anti-human CD3 monoclonal antibody OKT3.
    Adair JR; Athwal DS; Bodmer MW; Bright SM; Collins AM; Pulito VL; Rao PE; Reedman R; Rothermel AL; Xu D
    Hum Antibodies Hybridomas; 1994; 5(1-2):41-7. PubMed ID: 7858182
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 22.