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2. HPRT minigene generates chimeric transcripts as a by-product of gene targeting. Holcomb VB; Kim TM; Dumitrache LC; Ma SM; Chen MJ; Hasty P Genesis; 2007 May; 45(5):275-81. PubMed ID: 17457929 [TBL] [Abstract][Full Text] [Related]
3. Regulatory elements in the introns of the human HPRT gene are necessary for its expression in embryonic stem cells. Reid LH; Gregg RG; Smithies O; Koller BH Proc Natl Acad Sci U S A; 1990 Jun; 87(11):4299-303. PubMed ID: 2349238 [TBL] [Abstract][Full Text] [Related]
4. Inactivation of the mouse HPRT locus by a 203-bp retroposon insertion and a 55-kb gene-targeted deletion: establishment of new HPRT-deficient mouse embryonic stem cell lines. Tsuda H; Maynard-Currie CE; Reid LH; Yoshida T; Edamura K; Maeda N; Smithies O; Jakobovits A Genomics; 1997 Jun; 42(3):413-21. PubMed ID: 9205113 [TBL] [Abstract][Full Text] [Related]
5. Stability of HPRT marker gene expression at different gene-targeted loci: observing and overcoming a position effect. Melton DW; Ketchen AM; Selfridge J Nucleic Acids Res; 1997 Oct; 25(19):3937-43. PubMed ID: 9380520 [TBL] [Abstract][Full Text] [Related]
6. A position- and orientation-dependent element in the first intron is required for expression of the mouse hprt gene in embryonic stem cells. Magin TM; McEwan C; Milne M; Pow AM; Selfridge J; Melton DW Gene; 1992 Dec; 122(2):289-96. PubMed ID: 1487143 [TBL] [Abstract][Full Text] [Related]
7. Germ line transmission and expression of a corrected HPRT gene produced by gene targeting in embryonic stem cells. Thompson S; Clarke AR; Pow AM; Hooper ML; Melton DW Cell; 1989 Jan; 56(2):313-21. PubMed ID: 2912572 [TBL] [Abstract][Full Text] [Related]
8. Use of double-replacement gene targeting to replace the murine alpha-lactalbumin gene with its human counterpart in embryonic stem cells and mice. Stacey A; Schnieke A; McWhir J; Cooper J; Colman A; Melton DW Mol Cell Biol; 1994 Feb; 14(2):1009-16. PubMed ID: 8289781 [TBL] [Abstract][Full Text] [Related]
9. A pgk::hprt fusion as a selectable marker for targeting of genes in mouse embryonic stem cells: disruption of the T-cell receptor delta-chain-encoding gene. van der Lugt N; Maandag ER; te Riele H; Laird PW; Berns A Gene; 1991 Sep; 105(2):263-7. PubMed ID: 1834524 [TBL] [Abstract][Full Text] [Related]
10. Complementation of replication origin function in mouse embryonic stem cells by human DNA sequences. Cohen SM; Hatada S; Brylawski BP; Smithies O; Kaufman DG; Cordeiro-Stone M Genomics; 2004 Sep; 84(3):475-84. PubMed ID: 15498455 [TBL] [Abstract][Full Text] [Related]
11. Introduction of a subtle mutation into the Hox-2.6 locus in embryonic stem cells. Hasty P; RamÃrez-Solis R; Krumlauf R; Bradley A Nature; 1991 Mar; 350(6315):243-6. PubMed ID: 1672446 [TBL] [Abstract][Full Text] [Related]
12. Deletion and replacement of the mouse adult beta-globin genes by a "plug and socket" repeated targeting strategy. Detloff PJ; Lewis J; John SW; Shehee WR; Langenbach R; Maeda N; Smithies O Mol Cell Biol; 1994 Oct; 14(10):6936-43. PubMed ID: 7935410 [TBL] [Abstract][Full Text] [Related]
13. Generation of single-copy transgenic mouse embryos directly from ES cells by tetraploid embryo complementation. Misra RP; Bronson SK; Xiao Q; Garrison W; Li J; Zhao R; Duncan SA BMC Biotechnol; 2001; 1():12. PubMed ID: 11782291 [TBL] [Abstract][Full Text] [Related]
14. Testing an "in-out" targeting procedure for making subtle genomic modifications in mouse embryonic stem cells. Valancius V; Smithies O Mol Cell Biol; 1991 Mar; 11(3):1402-8. PubMed ID: 1996101 [TBL] [Abstract][Full Text] [Related]
15. Expression of the mouse HPRT gene: deletional analysis of the promoter region of an X-chromosome linked housekeeping gene. Melton DW; McEwan C; McKie AB; Reid AM Cell; 1986 Jan; 44(2):319-28. PubMed ID: 3455894 [TBL] [Abstract][Full Text] [Related]
16. High-throughput knock-in coupling gene targeting with the HPRT minigene and Cre-mediated recombination. Kim TM; Choi YJ; Ko JH; Hasty P Genesis; 2008 Dec; 46(12):732-7. PubMed ID: 18932256 [TBL] [Abstract][Full Text] [Related]
17. Targetted correction of a mutant HPRT gene in mouse embryonic stem cells. Doetschman T; Gregg RG; Maeda N; Hooper ML; Melton DW; Thompson S; Smithies O Nature; 1987 Dec 10-16; 330(6148):576-8. PubMed ID: 3683574 [TBL] [Abstract][Full Text] [Related]
18. Sequence of the rat hypoxanthine guanine phosphoribosyl transferase (HPRT) transcriptional promoter region in wild-type and mutant rat liver epithelial cell lines. Lazarus P; Calcagnotto A; Williams GM; Alvi N Mutat Res; 1994 Dec; 325(4):117-23. PubMed ID: 7527902 [TBL] [Abstract][Full Text] [Related]
19. Transformation of the gene for hypoxanthine phosphoribosyltransferase. Graf LH; Urlaub G; Chasin LA Somatic Cell Genet; 1979 Nov; 5(6):1031-44. PubMed ID: 397622 [TBL] [Abstract][Full Text] [Related]
20. Structure, expression, and mutation of the hypoxanthine phosphoribosyltransferase gene. Melton DW; Konecki DS; Brennand J; Caskey CT Proc Natl Acad Sci U S A; 1984 Apr; 81(7):2147-51. PubMed ID: 6326107 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]