These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

146 related articles for article (PubMed ID: 1446834)

  • 1. The use of a wild-type dihydrofolate reductase-encoding cDNA as a dominant selectable marker and induction of expression by methotrexate.
    Lo KM; Lynch CA; Gillies SD
    Gene; 1992 Nov; 121(2):365-9. PubMed ID: 1446834
    [TBL] [Abstract][Full Text] [Related]  

  • 2. High level expression of human proteins in murine hybridoma cells: induction by methotrexate in the absence of gene amplification.
    Lo KM; Gillies SD
    Biochim Biophys Acta; 1991 Feb; 1088(2):217-24. PubMed ID: 1672095
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Construction of a dominant selectable marker using a novel dihydrofolate reductase.
    Hussain A; Lewis D; Yu M; Melera PW
    Gene; 1992 Mar; 112(2):179-88. PubMed ID: 1555767
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Isolation and characterization of a variant dihydrofolate reductase cDNA from methotrexate-resistant murine L5178Y cells.
    McIvor RS; Simonsen CC
    Nucleic Acids Res; 1990 Dec; 18(23):7025-32. PubMed ID: 2263462
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Transfection of a nonactive site mutant murine DHFR cDNA (the tryptophan 15 mutant) into Chinese hamster ovary and mouse marrow progenitor cells imparts MTX resistance in vitro.
    Banerjee D; Zhao SC; Tong Y; Steinherz J; Gritsman K; Bertino JR
    Cancer Gene Ther; 1994 Sep; 1(3):181-4. PubMed ID: 7621249
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Generation of high-expressing cells by methotrexate amplification of destabilized dihydrofolate reductase selection marker.
    Ng SK
    Methods Mol Biol; 2012; 801():161-72. PubMed ID: 21987253
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Saturation mutagenesis at dihydrofolate reductase codons 22 and 31. A variety of amino acid substitutions conferring methotrexate resistance.
    Morris JA; McIvor RS
    Biochem Pharmacol; 1994 Mar; 47(7):1207-20. PubMed ID: 8161350
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Coupled expression of Ca2+ transport ATPase and a dihydrofolate reductase selectable marker in a mammalian cell system.
    Hussain A; Lewis D; Sumbilla C; Lai LC; Melera PW; Inesi G
    Arch Biochem Biophys; 1992 Aug; 296(2):539-46. PubMed ID: 1385939
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Expression of the plasmid-encoded type I dihydrofolate reductase gene in cultured mammalian cells: a novel selectable marker.
    Simonsen CS; Walter M; Levinson AD
    Nucleic Acids Res; 1988 Mar; 16(5):2235-46. PubMed ID: 3357775
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Selection for the expression of one form of Chinese hamster dihydrofolate reductase over another during growth in methotrexate.
    Hussain A; Yang H; Protzman J; Melera PW
    Gene; 1994 Jul; 144(2):277-82. PubMed ID: 8039714
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Selective expression of methotrexate-resistant dihydrofolate reductase (DHFR) activity in mice transduced with DHFR retrovirus and administered methotrexate.
    Vinh DB; McIvor RS
    J Pharmacol Exp Ther; 1993 Nov; 267(2):989-96. PubMed ID: 8246174
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Stimulation of dihydrofolate reductase promoter activity by antimetabolic drugs.
    Eastman HB; Swick AG; Schmitt MC; Azizkhan JC
    Proc Natl Acad Sci U S A; 1991 Oct; 88(19):8572-6. PubMed ID: 1833762
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Improved vectors for stable expression of foreign genes in mammalian cells by use of the untranslated leader sequence from EMC virus.
    Kaufman RJ; Davies MV; Wasley LC; Michnick D
    Nucleic Acids Res; 1991 Aug; 19(16):4485-90. PubMed ID: 1653417
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Coexpression of cytidine deaminase and mutant dihydrofolate reductase by a bicistronic retroviral vector confers resistance to cytosine arabinoside and methotrexate.
    Beauséjour CM; Le NL; Létourneau S; Cournoyer D; Momparler RL
    Hum Gene Ther; 1998 Nov; 9(17):2537-44. PubMed ID: 9853520
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Transfection of DHFR- and DHFR+ mammalian cells using methotrexate-resistant mutants of mouse dihydrofolate reductase.
    Thillet J; Pictet R
    FEBS Lett; 1990 Sep; 269(2):450-3. PubMed ID: 2401371
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Methotrexate selection of long-term culture initiating cells following transduction of CD34(+) cells with a retrovirus containing a mutated human dihydrofolate reductase gene.
    Takebe N; Xu LC; MacKenzie KL; Bertino JR; Moore MA
    Cancer Gene Ther; 2002 Mar; 9(3):308-20. PubMed ID: 11896448
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Transfection with a cDNA encoding a Ser31 or Ser34 mutant human dihydrofolate reductase into Chinese hamster ovary and mouse marrow progenitor cells confers methotrexate resistance.
    Banerjee D; Schweitzer BI; Volkenandt M; Li MX; Waltham M; Mineishi S; Zhao SC; Bertino JR
    Gene; 1994 Feb; 139(2):269-74. PubMed ID: 8112617
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Selection for methotrexate resistance in mammalian cells bearing a Drosophila dihydrofolate reductase transgene: Methotrexate resistance in transgenic mammalian cells.
    Affleck JG; Nowickyj SM; Walker VK
    Cell Biol Toxicol; 2010 Apr; 26(2):117-26. PubMed ID: 19337845
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Efficient protection from methotrexate toxicity and selection of transduced human hematopoietic cells following gene transfer of dihydrofolate reductase mutants.
    Meisel R; Bardenheuer W; Strehblow C; Sorg UR; Elmaagacli A; Seeber S; Flasshove M; Moritz T
    Exp Hematol; 2003 Dec; 31(12):1215-22. PubMed ID: 14662327
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Methotrexate-induced overexpression of functional glucocorticoid receptors in Chinese hamster ovary cells.
    Bellingham DL; Sar M; Cidlowski JA
    Mol Cell Endocrinol; 1992 Feb; 83(2-3):153-71. PubMed ID: 1547909
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.