225 related articles for article (PubMed ID: 14500624)
1. Cuttine edge: diabetes-associated quantitative trait locus, Idd4, is responsible for the IL-12p40 overexpression defect in nonobese diabetic (NOD) mice.
Simpson PB; Mistry MS; Maki RA; Yang W; Schwarz DA; Johnson EB; Lio FM; Alleva DG
J Immunol; 2003 Oct; 171(7):3333-7. PubMed ID: 14500624
[TBL] [Abstract][Full Text] [Related]
2. Aberrant macrophage cytokine production is a conserved feature among autoimmune-prone mouse strains: elevated interleukin (IL)-12 and an imbalance in tumor necrosis factor-alpha and IL-10 define a unique cytokine profile in macrophages from young nonobese diabetic mice.
Alleva DG; Pavlovich RP; Grant C; Kaser SB; Beller DI
Diabetes; 2000 Jul; 49(7):1106-15. PubMed ID: 10909966
[TBL] [Abstract][Full Text] [Related]
3. Molecular genetic analysis of the Idd4 locus implicates the IFN response in type 1 diabetes susceptibility in nonobese diabetic mice.
Ivakine EA; Gulban OM; Mortin-Toth SM; Wankiewicz E; Scott C; Spurrell D; Canty A; Danska JS
J Immunol; 2006 Mar; 176(5):2976-90. PubMed ID: 16493056
[TBL] [Abstract][Full Text] [Related]
4. Identification of the inflammasome Nlrp1b as the candidate gene conferring diabetes risk at the Idd4.1 locus in the nonobese diabetic mouse.
Motta VN; Markle JG; Gulban O; Mortin-Toth S; Liao KC; Mogridge J; Steward CA; Danska JS
J Immunol; 2015 Jun; 194(12):5663-73. PubMed ID: 25964492
[TBL] [Abstract][Full Text] [Related]
5. SJL and NOD macrophages are uniquely characterized by genetically programmed, elevated expression of the IL-12(p40) gene, suggesting a conserved pathway for the induction of organ-specific autoimmunity.
Alleva DG; Johnson EB; Wilson J; Beller DI; Conlon PJ
J Leukoc Biol; 2001 Mar; 69(3):440-8. PubMed ID: 11261792
[TBL] [Abstract][Full Text] [Related]
6. Distinct pathways for NF-kappa B regulation are associated with aberrant macrophage IL-12 production in lupus- and diabetes-prone mouse strains.
Liu J; Beller DI
J Immunol; 2003 May; 170(9):4489-96. PubMed ID: 12707325
[TBL] [Abstract][Full Text] [Related]
7. Nonobese diabetic mouse congenic analysis reveals chromosome 11 locus contributing to diabetes susceptibility, macrophage STAT5 dysfunction, and granulocyte-macrophage colony-stimulating factor overproduction.
Litherland SA; Grebe KM; Belkin NS; Paek E; Elf J; Atkinson M; Morel L; Clare-Salzler MJ; McDuffie M
J Immunol; 2005 Oct; 175(7):4561-5. PubMed ID: 16177100
[TBL] [Abstract][Full Text] [Related]
8. The idd4 locus displays sex-specific epistatic effects on type 1 diabetes susceptibility in nonobese diabetic mice.
Ivakine EA; Mortin-Toth SM; Gulban OM; Valova A; Canty A; Scott C; Danska JS
Diabetes; 2006 Dec; 55(12):3611-9. PubMed ID: 17130511
[TBL] [Abstract][Full Text] [Related]
9. Aberrant production of IL-12 by macrophages from several autoimmune-prone mouse strains is characterized by intrinsic and unique patterns of NF-kappa B expression and binding to the IL-12 p40 promoter.
Liu J; Beller D
J Immunol; 2002 Jul; 169(1):581-6. PubMed ID: 12077291
[TBL] [Abstract][Full Text] [Related]
10. Sex-specific effect of insulin-dependent diabetes 4 on regulation of diabetes pathogenesis in the nonobese diabetic mouse.
Ivakine EA; Fox CJ; Paterson AD; Mortin-Toth SM; Canty A; Walton DS; Aleksa K; Ito S; Danska JS
J Immunol; 2005 Jun; 174(11):7129-40. PubMed ID: 15905556
[TBL] [Abstract][Full Text] [Related]
11. Congenic mapping of the diabetogenic locus Idd4 to a 5.2-cM region of chromosome 11 in NOD mice: identification of two potential candidate subloci.
Grattan M; Mi QS; Meagher C; Delovitch TL
Diabetes; 2002 Jan; 51(1):215-23. PubMed ID: 11756344
[TBL] [Abstract][Full Text] [Related]
12. Visualization of IL-12/23p40 in vivo reveals immunostimulatory dendritic cell migrants that promote Th1 differentiation.
Reinhardt RL; Hong S; Kang SJ; Wang ZE; Locksley RM
J Immunol; 2006 Aug; 177(3):1618-27. PubMed ID: 16849470
[TBL] [Abstract][Full Text] [Related]
13. Crosses of NOD mice with the related NON strain. A polygenic model for IDDM.
McAleer MA; Reifsnyder P; Palmer SM; Prochazka M; Love JM; Copeman JB; Powell EE; Rodrigues NR; Prins JB; Serreze DV
Diabetes; 1995 Oct; 44(10):1186-95. PubMed ID: 7556956
[TBL] [Abstract][Full Text] [Related]
14. Murine gamma-herpesvirus-68-induced IL-12 contributes to the control of latent viral burden, but also contributes to viral-mediated leukocytosis.
Elsawa SF; Bost KL
J Immunol; 2004 Jan; 172(1):516-24. PubMed ID: 14688362
[TBL] [Abstract][Full Text] [Related]
15. Hydrogen peroxide increases interleukin-12 p40/p70 molecular ratio and induces Th2-predominant responses in mice.
Obata F; Hoshino A; Toyama A
Scand J Immunol; 2006 Feb; 63(2):125-30. PubMed ID: 16476011
[TBL] [Abstract][Full Text] [Related]
16. Characterization of PAF-AH Ib1 in NOD mice: PAF-AH may not be a candidate gene of the diabetes susceptibility Idd4.1 locus.
Mi QS; Zhou L; Grattan M; Wang ZZ; Sivilotti M; She JX; Delovitch TL
Ann N Y Acad Sci; 2006 Oct; 1079():147-52. PubMed ID: 17130546
[TBL] [Abstract][Full Text] [Related]
17. Through regulation of TCR expression levels, an Idd7 region gene(s) interactively contributes to the impaired thymic deletion of autoreactive diabetogenic CD8+ T cells in nonobese diabetic mice.
Serreze DV; Choisy-Rossi CM; Grier AE; Holl TM; Chapman HD; Gahagan JR; Osborne MA; Zhang W; King BL; Brown A; Roopenian D; Marron MP
J Immunol; 2008 Mar; 180(5):3250-9. PubMed ID: 18292549
[TBL] [Abstract][Full Text] [Related]
18. Nonobese diabetic congenic strain analysis of autoimmune diabetes reveals genetic complexity of the Idd18 locus and identifies Vav3 as a candidate gene.
Fraser HI; Dendrou CA; Healy B; Rainbow DB; Howlett S; Smink LJ; Gregory S; Steward CA; Todd JA; Peterson LB; Wicker LS
J Immunol; 2010 May; 184(9):5075-84. PubMed ID: 20363978
[TBL] [Abstract][Full Text] [Related]
19. Systemic administration of IL-18 promotes diabetes development in young nonobese diabetic mice.
Oikawa Y; Shimada A; Kasuga A; Morimoto J; Osaki T; Tahara H; Miyazaki T; Tashiro F; Yamato E; Miyazaki J; Saruta T
J Immunol; 2003 Dec; 171(11):5865-75. PubMed ID: 14634096
[TBL] [Abstract][Full Text] [Related]
20. Polymorphisms in the Il12b gene affect structure and expression of IL-12 in NOD and other autoimmune-prone mouse strains.
Ymer SI; Huang D; Penna G; Gregori S; Branson K; Adorini L; Morahan G
Genes Immun; 2002 May; 3(3):151-7. PubMed ID: 12070779
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]