BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

272 related articles for article (PubMed ID: 14500733)

  • 1. Identification and characterization of a third human, rat, and mouse collagen prolyl 4-hydroxylase isoenzyme.
    Kukkola L; Hieta R; Kivirikko KI; Myllyharju J
    J Biol Chem; 2003 Nov; 278(48):47685-93. PubMed ID: 14500733
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The peptide-substrate-binding domain of human collagen prolyl 4-hydroxylases. Backbone assignments, secondary structure, and binding of proline-rich peptides.
    Hieta R; Kukkola L; Permi P; Pirilä P; Kivirikko KI; Kilpeläinen I; Myllyharju J
    J Biol Chem; 2003 Sep; 278(37):34966-74. PubMed ID: 12824157
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Collagen prolyl 4-hydroxylase tetramers and dimers show identical decreases in Km values for peptide substrates with increasing chain length: mutation of one of the two catalytic sites in the tetramer inactivates the enzyme by more than half.
    Kukkola L; Koivunen P; Pakkanen O; Page AP; Myllyharju J
    J Biol Chem; 2004 Apr; 279(18):18656-61. PubMed ID: 14985345
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Cloning, baculovirus expression, and characterization of a second mouse prolyl 4-hydroxylase alpha-subunit isoform: formation of an alpha 2 beta 2 tetramer with the protein disulfide-isomerase/beta subunit.
    Helaakoski T; Annunen P; Vuori K; MacNeil IA; Pihlajaniemi T; Kivirikko KI
    Proc Natl Acad Sci U S A; 1995 May; 92(10):4427-31. PubMed ID: 7753822
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Baculovirus expression of two protein disulphide isomerase isoforms from Caenorhabditis elegans and characterization of prolyl 4-hydroxylases containing one of these polypeptides as their beta subunit.
    Veijola J; Annunen P; Koivunen P; Page AP; Pihlajaniemi T; Kivirikko KI
    Biochem J; 1996 Aug; 317 ( Pt 3)(Pt 3):721-9. PubMed ID: 8760355
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Characterization of a novel Caenorhabditis elegans prolyl 4-hydroxylase with a unique substrate specificity and restricted expression in the pharynx and excretory duct.
    Keskiaho K; Kukkola L; Page AP; Winter AD; Vuoristo J; Sormunen R; Nissi R; Riihimaa P; Myllyharju J
    J Biol Chem; 2008 Apr; 283(16):10679-89. PubMed ID: 18276589
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Characterization of a second Arabidopsis thaliana prolyl 4-hydroxylase with distinct substrate specificity.
    Tiainen P; Myllyharju J; Koivunen P
    J Biol Chem; 2005 Jan; 280(2):1142-8. PubMed ID: 15528200
    [TBL] [Abstract][Full Text] [Related]  

  • 8. ERp60 does not substitute for protein disulphide isomerase as the beta-subunit of prolyl 4-hydroxylase.
    Koivunen P; Helaakoski T; Annunen P; Veijola J; Räisänen S; Pihlajaniemi T; Kivirikko KI
    Biochem J; 1996 Jun; 316 ( Pt 2)(Pt 2):599-605. PubMed ID: 8687406
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Cloning of the human prolyl 4-hydroxylase alpha subunit isoform alpha(II) and characterization of the type II enzyme tetramer. The alpha(I) and alpha(II) subunits do not form a mixed alpha(I)alpha(II)beta2 tetramer.
    Annunen P; Helaakoski T; Myllyharju J; Veijola J; Pihlajaniemi T; Kivirikko KI
    J Biol Chem; 1997 Jul; 272(28):17342-8. PubMed ID: 9211872
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Cloning and characterization of a low molecular weight prolyl 4-hydroxylase from Arabidopsis thaliana. Effective hydroxylation of proline-rich, collagen-like, and hypoxia-inducible transcription factor alpha-like peptides.
    Hieta R; Myllyharju J
    J Biol Chem; 2002 Jun; 277(26):23965-71. PubMed ID: 11976332
    [TBL] [Abstract][Full Text] [Related]  

  • 11. A hypodermally expressed prolyl 4-hydroxylase from the filarial nematode Brugia malayi is soluble and active in the absence of protein disulfide isomerase.
    Winter AD; Myllyharju J; Page AP
    J Biol Chem; 2003 Jan; 278(4):2554-62. PubMed ID: 12417582
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Differences in collagen prolyl 4-hydroxylase assembly between two Caenorhabditis nematode species despite high amino acid sequence identity of the enzyme subunits.
    Winter AD; Keskiaho K; Kukkola L; McCormack G; Felix MA; Myllyharju J; Page AP
    Matrix Biol; 2007 Jun; 26(5):382-95. PubMed ID: 17321733
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Catalytic properties of the asparaginyl hydroxylase (FIH) in the oxygen sensing pathway are distinct from those of its prolyl 4-hydroxylases.
    Koivunen P; Hirsilä M; Günzler V; Kivirikko KI; Myllyharju J
    J Biol Chem; 2004 Mar; 279(11):9899-904. PubMed ID: 14701857
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Cloning, baculovirus expression, and characterization of the alpha subunit of prolyl 4-hydroxylase from the nematode Caenorhabditis elegans. This alpha subunit forms an active alpha beta dimer with the human protein disulfide isomerase/beta subunit.
    Veijola J; Koivunen P; Annunen P; Pihlajaniemi T; Kivirikko KI
    J Biol Chem; 1994 Oct; 269(43):26746-53. PubMed ID: 7929409
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The exoskeleton collagens in Caenorhabditis elegans are modified by prolyl 4-hydroxylases with unique combinations of subunits.
    Myllyharju J; Kukkola L; Winter AD; Page AP
    J Biol Chem; 2002 Aug; 277(32):29187-96. PubMed ID: 12036960
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Crystal structure of the collagen prolyl 4-hydroxylase (C-P4H) catalytic domain complexed with PDI: Toward a model of the C-P4H α
    Murthy AV; Sulu R; Lebedev A; Salo AM; Korhonen K; Venkatesan R; Tu H; Bergmann U; Jänis J; Laitaoja M; Ruddock LW; Myllyharju J; Koski MK; Wierenga RK
    J Biol Chem; 2022 Dec; 298(12):102614. PubMed ID: 36265586
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Identification of a novel proline-rich peptide-binding domain in prolyl 4-hydroxylase.
    Myllyharju J; Kivirikko KI
    EMBO J; 1999 Jan; 18(2):306-12. PubMed ID: 9889187
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The peptide-substrate-binding domain of collagen prolyl 4-hydroxylases is a tetratricopeptide repeat domain with functional aromatic residues.
    Pekkala M; Hieta R; Bergmann U; Kivirikko KI; Wierenga RK; Myllyharju J
    J Biol Chem; 2004 Dec; 279(50):52255-61. PubMed ID: 15456751
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Co-expression of the alpha subunit of human prolyl 4-hydroxylase with BiP polypeptide in insect cells leads to the formation of soluble and insoluble complexes. Soluble alpha-subunit-BiP complexes have no prolyl 4-hydroxylase activity.
    Veijola J; Pihlajaniemi T; Kivirikko KI
    Biochem J; 1996 Apr; 315 ( Pt 2)(Pt 2):613-8. PubMed ID: 8615837
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Characterization of the human prolyl 4-hydroxylase tetramer and its multifunctional protein disulfide-isomerase subunit synthesized in a baculovirus expression system.
    Vuori K; Pihlajaniemi T; Marttila M; Kivirikko KI
    Proc Natl Acad Sci U S A; 1992 Aug; 89(16):7467-70. PubMed ID: 1323838
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 14.