BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

170 related articles for article (PubMed ID: 14503864)

  • 1. Unexpected binding mode for 2'-phosphoadenosine-based nucleotide inhibitors in complex with human angiogenin revealed by heteronuclear NMR spectroscopy.
    Tonan K; Xu P; Jenkins JL; Russo A; Shapiro R; Ni F
    Biochemistry; 2003 Sep; 42(38):11137-49. PubMed ID: 14503864
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Toward rational design of ribonuclease inhibitors: high-resolution crystal structure of a ribonuclease A complex with a potent 3',5'-pyrophosphate-linked dinucleotide inhibitor.
    Leonidas DD; Shapiro R; Irons LI; Russo N; Acharya KR
    Biochemistry; 1999 Aug; 38(32):10287-97. PubMed ID: 10441122
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Analysis of the interactions of human ribonuclease inhibitor with angiogenin and ribonuclease A by mutagenesis: importance of inhibitor residues inside versus outside the C-terminal "hot spot".
    Shapiro R; Ruiz-Gutierrez M; Chen CZ
    J Mol Biol; 2000 Sep; 302(2):497-519. PubMed ID: 10970748
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Binding of phosphate and pyrophosphate ions at the active site of human angiogenin as revealed by X-ray crystallography.
    Leonidas DD; Chavali GB; Jardine AM; Li S; Shapiro R; Acharya KR
    Protein Sci; 2001 Aug; 10(8):1669-76. PubMed ID: 11468363
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Crystal structures of ribonuclease A complexes with 5'-diphosphoadenosine 3'-phosphate and 5'-diphosphoadenosine 2'-phosphate at 1.7 A resolution.
    Leonidas DD; Shapiro R; Irons LI; Russo N; Acharya KR
    Biochemistry; 1997 May; 36(18):5578-88. PubMed ID: 9154942
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Identification of small-molecule inhibitors of human angiogenin and characterization of their binding interactions guided by computational docking.
    Jenkins JL; Shapiro R
    Biochemistry; 2003 Jun; 42(22):6674-87. PubMed ID: 12779322
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Temperature dependence of the backbone dynamics of ribonuclease A in the ground state and bound to the inhibitor 5'-phosphothymidine (3'-5')pyrophosphate adenosine 3'-phosphate.
    Kovrigin EL; Cole R; Loria JP
    Biochemistry; 2003 May; 42(18):5279-91. PubMed ID: 12731869
    [TBL] [Abstract][Full Text] [Related]  

  • 8. High-resolution crystal structures of ribonuclease A complexed with adenylic and uridylic nucleotide inhibitors. Implications for structure-based design of ribonucleolytic inhibitors.
    Leonidas DD; Chavali GB; Oikonomakos NG; Chrysina ED; Kosmopoulou MN; Vlassi M; Frankling C; Acharya KR
    Protein Sci; 2003 Nov; 12(11):2559-74. PubMed ID: 14573867
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Superadditive and subadditive effects of "hot spot" mutations within the interfaces of placental ribonuclease inhibitor with angiogenin and ribonuclease A.
    Chen CZ; Shapiro R
    Biochemistry; 1999 Jul; 38(29):9273-85. PubMed ID: 10413501
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Cleavage of 3',5'-pyrophosphate-linked dinucleotides by ribonuclease A and angiogenin.
    Jardine AM; Leonidas DD; Jenkins JL; Park C; Raines RT; Acharya KR; Shapiro R
    Biochemistry; 2001 Aug; 40(34):10262-72. PubMed ID: 11513604
    [TBL] [Abstract][Full Text] [Related]  

  • 11. 5'-Modified pyrimidine nucleosides as inhibitors of ribonuclease A.
    Samanta A; Dasgupta S; Pathak T
    Bioorg Med Chem; 2011 Apr; 19(7):2478-84. PubMed ID: 21420869
    [TBL] [Abstract][Full Text] [Related]  

  • 12. 5'-Diphosphoadenosine 3'-phosphate is a potent inhibitor of bovine pancreatic ribonuclease A.
    Russo N; Shapiro R; Vallee BL
    Biochem Biophys Res Commun; 1997 Feb; 231(3):671-4. PubMed ID: 9070868
    [TBL] [Abstract][Full Text] [Related]  

  • 13. A combined kinetic and modeling study of the catalytic center subsites of human angiogenin.
    Russo N; Acharya KR; Vallee BL; Shapiro R
    Proc Natl Acad Sci U S A; 1996 Jan; 93(2):804-8. PubMed ID: 8570639
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Using proton nuclear magnetic resonance to study the mode of ribonuclease A inhibition by competitive and noncompetitive inhibitors.
    Ghosh KS; Debnath J; Pathak T; Dasgupta S
    Bioorg Med Chem Lett; 2008 Oct; 18(20):5503-6. PubMed ID: 18812256
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Site-specific mutagenesis reveals differences in the structural bases for tight binding of RNase inhibitor to angiogenin and RNase A.
    Chen CZ; Shapiro R
    Proc Natl Acad Sci U S A; 1997 Mar; 94(5):1761-6. PubMed ID: 9050852
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Inhibition of mammalian ribonucleases by endogenous adenosine dinucleotides.
    Kumar K; Jenkins JL; Jardine AM; Shapiro R
    Biochem Biophys Res Commun; 2003 Jan; 300(1):81-6. PubMed ID: 12480524
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Molecular recognition of human angiogenin by placental ribonuclease inhibitor--an X-ray crystallographic study at 2.0 A resolution.
    Papageorgiou AC; Shapiro R; Acharya KR
    EMBO J; 1997 Sep; 16(17):5162-77. PubMed ID: 9311977
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Mechanism of ribonuclease inhibition by ribonuclease inhibitor protein based on the crystal structure of its complex with ribonuclease A.
    Kobe B; Deisenhofer J
    J Mol Biol; 1996 Dec; 264(5):1028-43. PubMed ID: 9000628
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Selective abolition of pancreatic RNase binding to its inhibitor protein.
    Kumar K; Brady M; Shapiro R
    Proc Natl Acad Sci U S A; 2004 Jan; 101(1):53-8. PubMed ID: 14681553
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The binding of IMP to ribonuclease A.
    Hatzopoulos GN; Leonidas DD; Kardakaris R; Kobe J; Oikonomakos NG
    FEBS J; 2005 Aug; 272(15):3988-4001. PubMed ID: 16045769
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.