BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

520 related articles for article (PubMed ID: 14503875)

  • 1. Mutagenesis of benzo[a]pyrene diol epoxide in yeast: requirement for DNA polymerase zeta and involvement of DNA polymerase eta.
    Xie Z; Braithwaite E; Guo D; Zhao B; Geacintov NE; Wang Z
    Biochemistry; 2003 Sep; 42(38):11253-62. PubMed ID: 14503875
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Poleta, Polzeta and Rev1 together are required for G to T transversion mutations induced by the (+)- and (-)-trans-anti-BPDE-N2-dG DNA adducts in yeast cells.
    Zhao B; Wang J; Geacintov NE; Wang Z
    Nucleic Acids Res; 2006; 34(2):417-25. PubMed ID: 16415180
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Mutagenic properties of 3-(deoxyguanosin-N2-yl)-2-acetylaminofluorene, a persistent acetylaminofluorene-derived DNA adduct in mammalian cells.
    Yasui M; Dong H; Bonala RR; Suzuki N; Ohmori H; Hanaoka F; Johnson F; Grollman AP; Shibutani S
    Biochemistry; 2004 Nov; 43(47):15005-13. PubMed ID: 15554708
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Molecular characterization of mutation and comparison of mutation profiles in the hprt gene of Chinese hamster ovary cells treated with benzo[a]pyrene trans-7,8-diol-anti-9,10-epoxide, 1-nitrobenzo[a]pyrene trans-7,8-diol-anti-9,10-epoxide, and 3-nitrobenzo[a]pyrene trans-7,8- diol-anti-9,10-epoxide.
    Zhan DJ; Heflich RH; Fu PP
    Environ Mol Mutagen; 1996; 27(1):19-29. PubMed ID: 8625944
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Mutagenic potential of benzo[a]pyrene-derived DNA adducts positioned in codon 273 of the human P53 gene.
    Dong H; Bonala RR; Suzuki N; Johnson F; Grollman AP; Shibutani S
    Biochemistry; 2004 Dec; 43(50):15922-8. PubMed ID: 15595848
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Phenylalanine 171 is a molecular brake for translesion synthesis across benzo[a]pyrene-guanine adducts by human DNA polymerase kappa.
    Sassa A; Niimi N; Fujimoto H; Katafuchi A; Grúz P; Yasui M; Gupta RC; Johnson F; Ohta T; Nohmi T
    Mutat Res; 2011 Jan; 718(1-2):10-7. PubMed ID: 21078407
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Decreased frequency and highly aberrant spectrum of ultraviolet-induced mutations in the hprt gene of mouse fibroblasts expressing antisense RNA to DNA polymerase zeta.
    Diaz M; Watson NB; Turkington G; Verkoczy LK; Klinman NR; McGregor WG
    Mol Cancer Res; 2003 Sep; 1(11):836-47. PubMed ID: 14517346
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Ability of adducts formed in a shuttle vector by reactive metabolites of 1-nitropyrene and benzo(a)pyrene to induce mutations when the plasmid replicates in human cells.
    Maher VM; Yang JL; McCormick JJ
    Acta Biol Hung; 1990; 41(1-3):173-86. PubMed ID: 2128787
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Two-step error-prone bypass of the (+)- and (-)-trans-anti-BPDE-N2-dG adducts by human DNA polymerases eta and kappa.
    Zhang Y; Wu X; Guo D; Rechkoblit O; Geacintov NE; Wang Z
    Mutat Res; 2002 Dec; 510(1-2):23-35. PubMed ID: 12459440
    [TBL] [Abstract][Full Text] [Related]  

  • 10. In vivo evidence that phenylalanine 171 acts as a molecular brake for translesion DNA synthesis across benzo[a]pyrene DNA adducts by human DNA polymerase κ.
    Sassa A; Suzuki T; Kanemaru Y; Niimi N; Fujimoto H; Katafuchi A; Grúz P; Yasui M; Gupta RC; Johnson F; Ohta T; Honma M; Adachi N; Nohmi T
    DNA Repair (Amst); 2014 Mar; 15():21-8. PubMed ID: 24461735
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The vital role of polymerase ζ and REV1 in mutagenic, but not correct, DNA synthesis across benzo[a]pyrene-dG and recruitment of polymerase ζ by REV1 to replication-stalled site.
    Hashimoto K; Cho Y; Yang IY; Akagi J; Ohashi E; Tateishi S; de Wind N; Hanaoka F; Ohmori H; Moriya M
    J Biol Chem; 2012 Mar; 287(12):9613-22. PubMed ID: 22303021
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Methylated CpG dinucleotides are the preferential targets for G-to-T transversion mutations induced by benzo[a]pyrene diol epoxide in mammalian cells: similarities with the p53 mutation spectrum in smoking-associated lung cancers.
    Yoon JH; Smith LE; Feng Z; Tang M; Lee CS; Pfeifer GP
    Cancer Res; 2001 Oct; 61(19):7110-7. PubMed ID: 11585742
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Translesion synthesis past estrogen-derived DNA adducts by human DNA polymerases eta and kappa.
    Suzuki N; Itoh S; Poon K; Masutani C; Hanaoka F; Ohmori H; Yoshizawa I; Shibutani S
    Biochemistry; 2004 May; 43(20):6304-11. PubMed ID: 15147214
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Benzo[a]pyrene diol epoxide-deoxyguanosine adducts are accurately bypassed by yeast DNA polymerase zeta in vitro.
    Simhadri S; Kramata P; Zajc B; Sayer JM; Jerina DM; Hinkle DC; Wei CS
    Mutat Res; 2002 Oct; 508(1-2):137-45. PubMed ID: 12379469
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Formation of lysine 63-linked poly-ubiquitin chains protects human lung cells against benzo[a]pyrene-diol-epoxide-induced mutagenicity.
    Langie SA; Knaapen AM; Ramaekers CH; Theys J; Brun J; Godschalk RW; van Schooten FJ; Lambin P; Gray DA; Wouters BG; Chiu RK
    DNA Repair (Amst); 2007 Jun; 6(6):852-62. PubMed ID: 17395554
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Fidelity of translesional synthesis past benzo[a]pyrene diol epoxide-2'-deoxyguanosine DNA adducts: marked effects of host cell, sequence context, and chirality.
    Moriya M; Spiegel S; Fernandes A; Amin S; Liu T; Geacintov N; Grollman AP
    Biochemistry; 1996 Dec; 35(51):16646-51. PubMed ID: 8988000
    [TBL] [Abstract][Full Text] [Related]  

  • 17. High DNA damage by benzo[a]pyrene 7,8-diol-9,10-epoxide in bronchial epithelial cells from patients with lung cancer: comparison with lung parenchyma.
    Rojas M; Marie B; Vignaud JM; Martinet N; Siat J; Grosdidier G; Cascorbi I; Alexandrov K
    Cancer Lett; 2004 Apr; 207(2):157-63. PubMed ID: 15072824
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Expression of human glutathione S-transferase P1 confers resistance to benzo[a]pyrene or benzo[a]pyrene-7,8-dihydrodiol mutagenesis, macromolecular alkylation and formation of stable N2-Gua-BPDE adducts in stably transfected V79MZ cells co-expressing hCYP1A1.
    Kushman ME; Kabler SL; Fleming MH; Ravoori S; Gupta RC; Doehmer J; Morrow CS; Townsend AJ
    Carcinogenesis; 2007 Jan; 28(1):207-14. PubMed ID: 16885195
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Formation of diastereomeric benzo[a]pyrene diol epoxide-guanine adducts in p53 gene-derived DNA sequences.
    Matter B; Wang G; Jones R; Tretyakova N
    Chem Res Toxicol; 2004 Jun; 17(6):731-41. PubMed ID: 15206894
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The role of hRev7, the accessory subunit of hPolζ, in translesion synthesis past DNA damage induced by benzo[a]pyrene diol epoxide (BPDE).
    Neal JA; Fletcher KL; McCormick JJ; Maher VM
    BMC Cell Biol; 2010 Dec; 11():97. PubMed ID: 21143968
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 26.