These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

119 related articles for article (PubMed ID: 14505682)

  • 21. Synthesis and biological evaluation of 17beta-hydroxysteroid dehydrogenase type 1 (17beta-HSD1) inhibitors based on a thieno[2,3-d]pyrimidin-4(3H)-one core.
    Lilienkampf A; Karkola S; Alho-Richmond S; Koskimies P; Johansson N; Huhtinen K; Vihko K; Wähälä K
    J Med Chem; 2009 Nov; 52(21):6660-71. PubMed ID: 19824648
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Synthesis and receptor binding of new thieno[2,3-d]-pyrimidines as selective ligands of 5-HT(3) receptors.
    Modica MN; Romeo G; Salerno L; Pittalà V; Siracusa MA; Mereghetti I; Cagnotto A; Mennini T; Gáspár R; Gál A; Falkay G; Palkó M; Maksay G; Fülöp F
    Arch Pharm (Weinheim); 2008 Jun; 341(6):333-43. PubMed ID: 18535994
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Synthesis and structure-activity relationships of (R)-1-alkyl-3-[2-(2-amino)phenethyl]-5-(2-fluorophenyl)-6-methyluracils as human GnRH receptor antagonists.
    Rowbottom MW; Tucci FC; Zhu YF; Guo Z; Gross TD; Reinhart GJ; Xie Q; Struthers RS; Saunders J; Chen C
    Bioorg Med Chem Lett; 2004 May; 14(9):2269-74. PubMed ID: 15081023
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Synthesis and pharmacological investigation of 3-subsituted-amino-2-methylsulfanyl-5,6,7,8-tetrahydro-3H-benzo[4,5]thieno[2,3-d]pyrimidin-4-ones as analgesic and anti-inflammatory agents.
    Alagarsamy V; Solomon VR; Deepa G; Parthiban P; Anjana GV
    Arch Pharm (Weinheim); 2007 Jul; 340(7):352-8. PubMed ID: 17610301
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Synthesis and structure-activity relationships of 1-arylmethyl-3-(1-methyl-2-amino)ethyl-5-aryl-6-methyluracils as antagonists of the human GnRH Receptor.
    Tucci FC; Zhu YF; Guo Z; Gross TD; Connors PJ; Struthers RS; Reinhart GJ; Saunders J; Chen C
    Bioorg Med Chem Lett; 2003 Oct; 13(19):3317-22. PubMed ID: 12951117
    [TBL] [Abstract][Full Text] [Related]  

  • 26. N-3-substituted pyrimidinones as potent, orally active, AT1 selective angiotensin II receptor antagonists.
    Salimbeni A; Canevotti R; Paleari F; Poma D; Caliari S; Fici F; Cirillo R; Renzetti AR; Subissi A; Belvisi L
    J Med Chem; 1995 Nov; 38(24):4806-20. PubMed ID: 7490730
    [TBL] [Abstract][Full Text] [Related]  

  • 27. 1H-cyclopentapyrimidine-2,4(1H,3H)-dione-related ionotropic glutamate receptors ligands. structure-activity relationships and identification of potent and Selective iGluR5 modulators.
    Butini S; Pickering DS; Morelli E; Coccone SS; Trotta F; De Angelis M; Guarino E; Fiorini I; Campiani G; Novellino E; Schousboe A; Christensen JK; Gemma S
    J Med Chem; 2008 Oct; 51(20):6614-8. PubMed ID: 18811139
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Design, synthesis and biological evaluations of N-Hydroxy thienopyrimidine-2,4-diones as inhibitors of HIV reverse transcriptase-associated RNase H.
    Kankanala J; Kirby KA; Huber AD; Casey MC; Wilson DJ; Sarafianos SG; Wang Z
    Eur J Med Chem; 2017 Dec; 141():149-161. PubMed ID: 29031062
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Synthesis and SAR development of novel mGluR1 antagonists for the treatment of chronic pain.
    Brumfield S; Korakas P; Silverman LS; Tulshian D; Matasi JJ; Qiang L; Bennett CE; Burnett DA; Greenlee WJ; Knutson CE; Wu WL; Sasikumar TK; Domalski M; Bertorelli R; Grilli M; Lozza G; Reggiani A; Li C
    Bioorg Med Chem Lett; 2012 Dec; 22(23):7223-6. PubMed ID: 23084894
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Synthesis and SAR of thieno[3,2-b]pyridinyl urea derivatives as urotensin-II receptor antagonists.
    Lim CJ; Oh SA; Lee BH; Oh KS; Yi KY
    Bioorg Med Chem Lett; 2014 Dec; 24(24):5832-5835. PubMed ID: 25452001
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Synthesis and pharmacological evaluation of thieno[2,3-d]pyrimidin-2,4-dione and 5H-pyrimido [5,4-b]indol-2,4-dione derivatives.
    Santagati NA; Caruso A; Cutuli VM; Caccamo F
    Farmaco; 1995 Oct; 50(10):689-95. PubMed ID: 8590576
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Synthesis and pharmacological activity of 2-alkylthio substituted thieno[2,3-d]pyrimidine-4-one and 5H-pyrimido [5,4-b]indol-4-one.
    Russo F; Santagati NA; Venturini R; Spampinato S
    Pharmazie; 1990 Jul; 45(7):493-5. PubMed ID: 2236192
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Synthesis and spasmolytic action of 2-substituted thienopyrimidin-4-one derivatives.
    Santagati NA; Prezzavento O; Bousquet E; Ronsisvalle G; Spampinato S
    J Pharm Pharmacol; 2002 May; 54(5):717-28. PubMed ID: 12005367
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Overlapping, nonidentical binding sites of different classes of nonpeptide antagonists for the human gonadotropin-releasing hormone receptor.
    Betz SF; Reinhart GJ; Lio FM; Chen C; Struthers RS
    J Med Chem; 2006 Jan; 49(2):637-47. PubMed ID: 16420049
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Synthesis of 2-mercapto-3-substituted-5,6-dimethylthieno[2,3-d] pyrimidin-4(3H)-ones as new analgesic, anti-inflammatory agents.
    Alagarsamy V; Vijayakumar S; Raja Solomon V
    Biomed Pharmacother; 2007 Jun; 61(5):285-91. PubMed ID: 17391907
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Discovery of the thieno[2,3-d]pyrimidine-2,4-dione derivative 21a: A potent and orally bioavailable gonadotropin-releasing hormone receptor antagonist.
    Zou F; Wang Y; Yu D; Liu C; Lu J; Zhao M; Ma M; Wang W; Jiang W; Gao Y; Zhang R; Zhang J; Ye L; Tian J
    Eur J Med Chem; 2022 Nov; 242():114679. PubMed ID: 35998545
    [TBL] [Abstract][Full Text] [Related]  

  • 37. New pyrrolopyrimidin-6-yl benzenesulfonamides: potent A2B adenosine receptor antagonists.
    Esteve C; Nueda A; Díaz JL; Beleta J; Cárdenas A; Lozoya E; Cadavid MI; Loza MI; Ryder H; Vidal B
    Bioorg Med Chem Lett; 2006 Jul; 16(14):3642-5. PubMed ID: 16697192
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Synthesis of thiophene and N-substituted thieno[3,2-d] pyrimidine derivatives as potent antitumor and antibacterial agents.
    Hafez HN; Alsalamah SA; El-Gazzar ABA
    Acta Pharm; 2017 Sep; 67(3):275-292. PubMed ID: 28858838
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Design, Synthesis and Anti-Proliferative Activities of 2,6-Substituted Thieno[3,2-d]pyrimidine Derivatives Containing Electrophilic Warheads.
    Zhang Q; Hu Z; Shen Q; Chen Y; Lu W
    Molecules; 2017 May; 22(5):. PubMed ID: 28498316
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Exploration of a new type of antimalarial compounds based on febrifugine.
    Kikuchi H; Yamamoto K; Horoiwa S; Hirai S; Kasahara R; Hariguchi N; Matsumoto M; Oshima Y
    J Med Chem; 2006 Jul; 49(15):4698-706. PubMed ID: 16854076
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 6.