These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
735 related articles for article (PubMed ID: 14506174)
1. Sensitization of pancreatic tumor xenografts to carmustine and temozolomide by inactivation of their O6-Methylguanine-DNA methyltransferase with O6-benzylguanine or O6-benzyl-2'-deoxyguanosine. Kokkinakis DM; Ahmed MM; Chendil D; Moschel RC; Pegg AE Clin Cancer Res; 2003 Sep; 9(10 Pt 1):3801-7. PubMed ID: 14506174 [TBL] [Abstract][Full Text] [Related]
2. Thresholds of O6-alkylguanine-DNA alkyltransferase which confer significant resistance of human glial tumor xenografts to treatment with 1,3-bis(2-chloroethyl)-1-nitrosourea or temozolomide. Kokkinakis DM; Bocangel DB; Schold SC; Moschel RC; Pegg AE Clin Cancer Res; 2001 Feb; 7(2):421-8. PubMed ID: 11234899 [TBL] [Abstract][Full Text] [Related]
3. Extended depletion of O6-methylguanine-DNA methyltransferase activity following O6-benzyl-2'-deoxyguanosine or O6-benzylguanine combined with streptozotocin treatment enhances 1,3-bis(2-chloroethyl)-1-nitrosourea cytotoxicity. Marathi UK; Dolan ME; Erickson LC Cancer Res; 1994 Aug; 54(16):4371-5. PubMed ID: 8044784 [TBL] [Abstract][Full Text] [Related]
4. Potentiation of BCNU antitumor efficacy by 9-substituted O6-benzylguanines. Effect of metabolism. Kokkinakis DM; Moschel RC; Pegg AE; Schold SC Cancer Chemother Pharmacol; 2000; 45(1):69-77. PubMed ID: 10647505 [TBL] [Abstract][Full Text] [Related]
5. Treatment of human brain tumor xenografts with O6-benzyl-2'-deoxyguanosine and BCNU. Schold SC; Kokkinakis DM; Rudy JL; Moschel RC; Pegg AE Cancer Res; 1996 May; 56(9):2076-81. PubMed ID: 8616853 [TBL] [Abstract][Full Text] [Related]
6. Role of O6-methylguanine-DNA methyltransferase in the resistance of pancreatic tumors to DNA alkylating agents. Kokkinakis DM; Ahmed MM; Delgado R; Fruitwala MM; Mohiuddin M; Albores-Saavedra J Cancer Res; 1997 Dec; 57(23):5360-8. PubMed ID: 9393761 [TBL] [Abstract][Full Text] [Related]
8. Eradication of human medulloblastoma tumor xenografts with a combination of O6-benzyl-2'-deoxyguanosine and 1,3-bis(2-chloroethyl)1-nitrosourea. Kokkinakis DM; Moschel RC; Pegg AE; Schold SC Clin Cancer Res; 1999 Nov; 5(11):3676-81. PubMed ID: 10589786 [TBL] [Abstract][Full Text] [Related]
9. Chemotherapy-induced O(6)-benzylguanine-resistant alkyltransferase mutations in mismatch-deficient colon cancer. Liu L; Schwartz S; Davis BM; Gerson SL Cancer Res; 2002 Jun; 62(11):3070-6. PubMed ID: 12036916 [TBL] [Abstract][Full Text] [Related]
10. O6-methylguanine-DNA methyltransferase (MGMT) transfectants of a 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU)-sensitive colon cancer cell line selectively repopulate heterogenous MGMT+/MGMT- xenografts after BCNU and O6-benzylguanine plus BCNU. Phillips WP; Willson JK; Markowitz SD; Zborowska E; Zaidi NH; Liu L; Gordon NH; Gerson SL Cancer Res; 1997 Nov; 57(21):4817-23. PubMed ID: 9354444 [TBL] [Abstract][Full Text] [Related]
11. Simultaneous protection of G156A methylguanine DNA methyltransferase gene-transduced hematopoietic progenitors and sensitization of tumor cells using O6-benzylguanine and temozolomide. Reese JS; Davis BM; Liu L; Gerson SL Clin Cancer Res; 1999 Jan; 5(1):163-9. PubMed ID: 9918215 [TBL] [Abstract][Full Text] [Related]
12. A single cycle of treatment with temozolomide, alone or combined with O(6)-benzylguanine, induces strong chemoresistance in melanoma cell clones in vitro: role of O(6)-methylguanine-DNA methyltransferase and the mismatch repair system. Alvino E; Castiglia D; Caporali S; Pepponi R; Caporaso P; Lacal PM; Marra G; Fischer F; Zambruno G; Bonmassar E; Jiricny J; D'Atri S Int J Oncol; 2006 Oct; 29(4):785-97. PubMed ID: 16964376 [TBL] [Abstract][Full Text] [Related]
13. Role of O6-methylguanine-DNA methyltransferase in protecting from alkylating agent-induced toxicity and mutations in mice. Hansen RJ; Nagasubramanian R; Delaney SM; Samson LD; Dolan ME Carcinogenesis; 2007 May; 28(5):1111-6. PubMed ID: 17116724 [TBL] [Abstract][Full Text] [Related]
14. Base excision repair as a therapeutic target in colon cancer. Liu L; Nakatsuru Y; Gerson SL Clin Cancer Res; 2002 Sep; 8(9):2985-91. PubMed ID: 12231545 [TBL] [Abstract][Full Text] [Related]
15. DeltaMGMT-transduced bone marrow infusion increases tolerance to O6-benzylguanine and 1,3-bis(2-chloroethyl)-1-nitrosourea and allows intensive therapy of 1,3-bis(2-chloroethyl)-1-nitrosourea-resistant human colon cancer xenografts. KoƧ ON; Reese JS; Davis BM; Liu L; Majczenko KJ; Gerson SL Hum Gene Ther; 1999 Apr; 10(6):1021-30. PubMed ID: 10223735 [TBL] [Abstract][Full Text] [Related]
16. Mismatch repair mutations override alkyltransferase in conferring resistance to temozolomide but not to 1,3-bis(2-chloroethyl)nitrosourea. Liu L; Markowitz S; Gerson SL Cancer Res; 1996 Dec; 56(23):5375-9. PubMed ID: 8968088 [TBL] [Abstract][Full Text] [Related]
17. O6-benzylguanine potentiates the antitumor effect of locally delivered carmustine against an intracranial rat glioma. Rhines LD; Sampath P; Dolan ME; Tyler BM; Brem H; Weingart J Cancer Res; 2000 Nov; 60(22):6307-10. PubMed ID: 11103789 [TBL] [Abstract][Full Text] [Related]
18. Mitochondrial targeting of human O6-methylguanine DNA methyltransferase protects against cell killing by chemotherapeutic alkylating agents. Cai S; Xu Y; Cooper RJ; Ferkowicz MJ; Hartwell JR; Pollok KE; Kelley MR Cancer Res; 2005 Apr; 65(8):3319-27. PubMed ID: 15833865 [TBL] [Abstract][Full Text] [Related]
19. Delayed repletion of O6-methylguanine-DNA methyltransferase resulting in failure to protect the human glioblastoma cell line SF767 from temozolomide-induced cytotoxicity. Hirose Y; Kreklau EL; Erickson LC; Berger MS; Pieper RO J Neurosurg; 2003 Mar; 98(3):591-8. PubMed ID: 12650433 [TBL] [Abstract][Full Text] [Related]
20. Hematopoietic expression of O(6)-methylguanine DNA methyltransferase-P140K allows intensive treatment of human glioma xenografts with combination O(6)-benzylguanine and 1,3-bis-(2-chloroethyl)-1-nitrosourea. Kreklau EL; Pollok KE; Bailey BJ; Liu N; Hartwell JR; Williams DA; Erickson LC Mol Cancer Ther; 2003 Dec; 2(12):1321-9. PubMed ID: 14707273 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]