These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

294 related articles for article (PubMed ID: 14506252)

  • 1. The von Hippel Lindau/hypoxia-inducible factor (HIF) pathway regulates the transcription of the HIF-proline hydroxylase genes in response to low oxygen.
    del Peso L; Castellanos MC; Temes E; Martin-Puig S; Cuevas Y; Olmos G; Landazuri MO
    J Biol Chem; 2003 Dec; 278(49):48690-5. PubMed ID: 14506252
    [TBL] [Abstract][Full Text] [Related]  

  • 2. A yeast three-hybrid system that reconstitutes mammalian hypoxia inducible factor regulatory machinery.
    Alcaide-German ML; Vara-Vega A; Garcia-Fernandez LF; Landazuri MO; del Peso L
    BMC Cell Biol; 2008 Apr; 9():18. PubMed ID: 18402654
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Hypoxia-inducible factor-1 (HIF-1) promotes its degradation by induction of HIF-alpha-prolyl-4-hydroxylases.
    Marxsen JH; Stengel P; Doege K; Heikkinen P; Jokilehto T; Wagner T; Jelkmann W; Jaakkola P; Metzen E
    Biochem J; 2004 Aug; 381(Pt 3):761-7. PubMed ID: 15104534
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Suppression of hypoxia-inducible factor 1alpha (HIF-1alpha) transcriptional activity by the HIF prolyl hydroxylase EGLN1.
    To KK; Huang LE
    J Biol Chem; 2005 Nov; 280(45):38102-7. PubMed ID: 16157596
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Identification of residues critical for regulation of protein stability and the transactivation function of the hypoxia-inducible factor-1alpha by the von Hippel-Lindau tumor suppressor gene product.
    Pereira T; Zheng X; Ruas JL; Tanimoto K; Poellinger L
    J Biol Chem; 2003 Feb; 278(9):6816-23. PubMed ID: 12468553
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Up-regulation of hypoxia-inducible factors HIF-1alpha and HIF-2alpha under normoxic conditions in renal carcinoma cells by von Hippel-Lindau tumor suppressor gene loss of function.
    Krieg M; Haas R; Brauch H; Acker T; Flamme I; Plate KH
    Oncogene; 2000 Nov; 19(48):5435-43. PubMed ID: 11114720
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Hypoxia up-regulates prolyl hydroxylase activity: a feedback mechanism that limits HIF-1 responses during reoxygenation.
    D'Angelo G; Duplan E; Boyer N; Vigne P; Frelin C
    J Biol Chem; 2003 Oct; 278(40):38183-7. PubMed ID: 12876291
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Oxygen-dependent ubiquitination and degradation of hypoxia-inducible factor requires nuclear-cytoplasmic trafficking of the von Hippel-Lindau tumor suppressor protein.
    Groulx I; Lee S
    Mol Cell Biol; 2002 Aug; 22(15):5319-36. PubMed ID: 12101228
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Identification of a region on hypoxia-inducible-factor prolyl 4-hydroxylases that determines their specificity for the oxygen degradation domains.
    Villar D; Vara-Vega A; Landázuri MO; Del Peso L
    Biochem J; 2007 Dec; 408(2):231-40. PubMed ID: 17725546
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Roles of the HIF-1 hypoxia-inducible factor during hypoxia response in Caenorhabditis elegans.
    Shen C; Nettleton D; Jiang M; Kim SK; Powell-Coffman JA
    J Biol Chem; 2005 May; 280(21):20580-8. PubMed ID: 15781453
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Activation of hypoxia-induced transcription in normoxia.
    Hägg M; Wennström S
    Exp Cell Res; 2005 May; 306(1):180-91. PubMed ID: 15878343
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Proline hydroxylation and gene expression.
    Kaelin WG
    Annu Rev Biochem; 2005; 74():115-28. PubMed ID: 15952883
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Regulation of HIF prolyl hydroxylases by hypoxia-inducible factors.
    Aprelikova O; Chandramouli GV; Wood M; Vasselli JR; Riss J; Maranchie JK; Linehan WM; Barrett JC
    J Cell Biochem; 2004 Jun; 92(3):491-501. PubMed ID: 15156561
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Depletion of intracellular ascorbate by the carcinogenic metals nickel and cobalt results in the induction of hypoxic stress.
    Salnikow K; Donald SP; Bruick RK; Zhitkovich A; Phang JM; Kasprzak KS
    J Biol Chem; 2004 Sep; 279(39):40337-44. PubMed ID: 15271983
    [TBL] [Abstract][Full Text] [Related]  

  • 15. OS-9 interacts with hypoxia-inducible factor 1alpha and prolyl hydroxylases to promote oxygen-dependent degradation of HIF-1alpha.
    Baek JH; Mahon PC; Oh J; Kelly B; Krishnamachary B; Pearson M; Chan DA; Giaccia AJ; Semenza GL
    Mol Cell; 2005 Feb; 17(4):503-12. PubMed ID: 15721254
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Copper-dependent activation of hypoxia-inducible factor (HIF)-1: implications for ceruloplasmin regulation.
    Martin F; Linden T; Katschinski DM; Oehme F; Flamme I; Mukhopadhyay CK; Eckhardt K; Tröger J; Barth S; Camenisch G; Wenger RH
    Blood; 2005 Jun; 105(12):4613-9. PubMed ID: 15741220
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The multifaceted role of EGLN family prolyl hydroxylases in cancer: going beyond HIF regulation.
    Strocchi S; Reggiani F; Gobbi G; Ciarrocchi A; Sancisi V
    Oncogene; 2022 Jul; 41(29):3665-3679. PubMed ID: 35705735
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The von Hippel-Lindau tumor suppressor, hypoxia-inducible factor-1 (HIF-1) degradation, and cancer pathogenesis.
    Pugh CW; Ratcliffe PJ
    Semin Cancer Biol; 2003 Feb; 13(1):83-9. PubMed ID: 12507560
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Activation of the hypoxia-inducible factor-pathway and stimulation of angiogenesis by application of prolyl hydroxylase inhibitors.
    Warnecke C; Griethe W; Weidemann A; Jürgensen JS; Willam C; Bachmann S; Ivashchenko Y; Wagner I; Frei U; Wiesener M; Eckardt KU
    FASEB J; 2003 Jun; 17(9):1186-8. PubMed ID: 12709400
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Dynamic HIF1A regulation during human placental development.
    Ietta F; Wu Y; Winter J; Xu J; Wang J; Post M; Caniggia I
    Biol Reprod; 2006 Jul; 75(1):112-21. PubMed ID: 16611863
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 15.