BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

183 related articles for article (PubMed ID: 14507715)

  • 1. Dynamic NMR structures of [Rp]- and [Sp]-phosphorothioated DNA-RNA hybrids: is flexibility required for RNase H recognition?
    Tonelli M; Ulyanov NB; Billeci TM; Karwowski B; Guga P; Stec WJ; James TL
    Biophys J; 2003 Oct; 85(4):2525-38. PubMed ID: 14507715
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Structural effect of complete [Rp]-phosphorothioate and phosphorodithioate substitutions in the DNA strand of a model antisense inhibitor-target RNA complex.
    Furrer P; Billeci TM; Donati A; Kojima C; Karwowski B; Sierzchala A; Stec W; James TL
    J Mol Biol; 1999 Jan; 285(4):1609-22. PubMed ID: 9917400
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Structure of a stereoregular phosphorothioate DNA/RNA duplex.
    Bachelin M; Hessler G; Kurz G; Hacia JG; Dervan PB; Kessler H
    Nat Struct Biol; 1998 Apr; 5(4):271-6. PubMed ID: 9546216
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Structure and dynamics of a DNA.RNA hybrid duplex with a chiral phosphorothioate moiety: NMR and molecular dynamics with conventional and time-averaged restraints.
    González C; Stec W; Reynolds MA; James TL
    Biochemistry; 1995 Apr; 34(15):4969-82. PubMed ID: 7711019
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Structural study of a DNA.RNA hybrid duplex with a chiral phosphorothioate moiety by NMR: extraction of distance and torsion angle constraints and imino proton exchange rates.
    González C; Stec W; Kobylanska A; Hogrefe RI; Reynolds M; James TL
    Biochemistry; 1994 Sep; 33(37):11062-72. PubMed ID: 7537083
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Structural basis of cleavage by RNase H of hybrids of arabinonucleic acids and RNA.
    Minasov G; Teplova M; Nielsen P; Wengel J; Egli M
    Biochemistry; 2000 Apr; 39(13):3525-32. PubMed ID: 10736151
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Structural basis of the RNase H1 activity on stereo regular borano phosphonate DNA/RNA hybrids.
    Johnson CN; Spring AM; Sergueev D; Shaw BR; Germann MW
    Biochemistry; 2011 May; 50(19):3903-12. PubMed ID: 21443203
    [TBL] [Abstract][Full Text] [Related]  

  • 8. High-resolution NMR of an antisense DNA x RNA hybrid containing alternating chirally pure Rp methylphosphonates in the DNA backbone.
    Mujeeb A; Reynolds MA; James TL
    Biochemistry; 1997 Mar; 36(9):2371-9. PubMed ID: 9054542
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Metropolis Monte Carlo calculations of DNA structure using internal coordinates and NMR distance restraints: an alternative method for generating a high-resolution solution structure.
    Ulyanov NB; Schmitz U; James TL
    J Biomol NMR; 1993 Sep; 3(5):547-68. PubMed ID: 8219740
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Solution structure of a DNA octamer containing the Pribnow box via restrained molecular dynamics simulation with distance and torsion angle constraints derived from two-dimensional nuclear magnetic resonance spectral fitting.
    Schmitz U; Sethson I; Egan WM; James TL
    J Mol Biol; 1992 Sep; 227(2):510-31. PubMed ID: 1404366
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Structure of a DNA:RNA hybrid duplex. Why RNase H does not cleave pure RNA.
    Fedoroff OYu ; Salazar M; Reid BR
    J Mol Biol; 1993 Oct; 233(3):509-23. PubMed ID: 8411159
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Insights into the dynamic nature of DNA duplex structure via analysis of nuclear Overhauser effect intensities.
    Tonelli M; James TL
    Biochemistry; 1998 Aug; 37(33):11478-87. PubMed ID: 9708983
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Binding affinity and specificity of Escherichia coli RNase H1: impact on the kinetics of catalysis of antisense oligonucleotide-RNA hybrids.
    Lima WF; Crooke ST
    Biochemistry; 1997 Jan; 36(2):390-8. PubMed ID: 9003192
    [TBL] [Abstract][Full Text] [Related]  

  • 14. A critical survey of the structure-function of the antisense oligo/RNA heteroduplex as substrate for RNase H.
    Zamaratski E; Pradeepkumar PI; Chattopadhyaya J
    J Biochem Biophys Methods; 2001 May; 48(3):189-208. PubMed ID: 11384757
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Two-dimensional 1H and 31P NMR spectra and restrained molecular dynamics structure of an oligodeoxyribonucleotide duplex refined via a hybrid relaxation matrix procedure.
    Powers R; Jones CR; Gorenstein DG
    J Biomol Struct Dyn; 1990 Oct; 8(2):253-94. PubMed ID: 2268403
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Structure and stability of the consecutive stereoregulated chiral phosphorothioate DNA duplex.
    Kanaori K; Tamura Y; Wada T; Nishi M; Kanehara H; Morii T; Tajima K; Makino K
    Biochemistry; 1999 Dec; 38(49):16058-66. PubMed ID: 10587428
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Solution structure of an LNA hybridized to DNA: NMR study of the d(CT(L)GCT(L)T(L)CT(L)GC):d(GCAGAAGCAG) duplex containing four locked nucleotides.
    Nielsen KE; Singh SK; Wengel J; Jacobsen JP
    Bioconjug Chem; 2000; 11(2):228-38. PubMed ID: 10725100
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Structure of a DNA duplex that contains alpha-anomeric nucleotides and 3'-3' and 5'-5' phosphodiester linkages: coexistence of parallel and antiparallel DNA.
    Aramini JM; Kalisch BW; Pon RT; van de Sande JH; Germann MW
    Biochemistry; 1996 Jul; 35(29):9355-65. PubMed ID: 8755713
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Solution structure of a conserved DNA sequence from the HIV-1 genome: restrained molecular dynamics simulation with distance and torsion angle restraints derived from two-dimensional NMR spectra.
    Mujeeb A; Kerwin SM; Kenyon GL; James TL
    Biochemistry; 1993 Dec; 32(49):13419-31. PubMed ID: 8257678
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Solution structure of r(gaggacug):d(CAGTCCTC) hybrid: implications for the initiation of HIV-1 (+)-strand synthesis.
    Fedoroff OY; Ge Y; Reid BR
    J Mol Biol; 1997 Jun; 269(2):225-39. PubMed ID: 9191067
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.