365 related articles for article (PubMed ID: 14512875)
1. p38 MAPK mediates fibrogenic signal through Smad3 phosphorylation in rat myofibroblasts.
Furukawa F; Matsuzaki K; Mori S; Tahashi Y; Yoshida K; Sugano Y; Yamagata H; Matsushita M; Seki T; Inagaki Y; Nishizawa M; Fujisawa J; Inoue K
Hepatology; 2003 Oct; 38(4):879-89. PubMed ID: 14512875
[TBL] [Abstract][Full Text] [Related]
2. Transforming growth factor-beta and platelet-derived growth factor signal via c-Jun N-terminal kinase-dependent Smad2/3 phosphorylation in rat hepatic stellate cells after acute liver injury.
Yoshida K; Matsuzaki K; Mori S; Tahashi Y; Yamagata H; Furukawa F; Seki T; Nishizawa M; Fujisawa J; Okazaki K
Am J Pathol; 2005 Apr; 166(4):1029-39. PubMed ID: 15793284
[TBL] [Abstract][Full Text] [Related]
3. Transdifferentiation-dependent expression of alpha-SMA in hepatic stellate cells does not involve TGF-beta pathways leading to coinduction of collagen type I and thrombospondin-2.
Lindert S; Wickert L; Sawitza I; Wiercinska E; Gressner AM; Dooley S; Breitkopf K
Matrix Biol; 2005 May; 24(3):198-207. PubMed ID: 15905080
[TBL] [Abstract][Full Text] [Related]
4. TGF-beta and HGF transmit the signals through JNK-dependent Smad2/3 phosphorylation at the linker regions.
Mori S; Matsuzaki K; Yoshida K; Furukawa F; Tahashi Y; Yamagata H; Sekimoto G; Seki T; Matsui H; Nishizawa M; Fujisawa J; Okazaki K
Oncogene; 2004 Sep; 23(44):7416-29. PubMed ID: 15326485
[TBL] [Abstract][Full Text] [Related]
5. Differential regulation of TGF-beta signal in hepatic stellate cells between acute and chronic rat liver injury.
Tahashi Y; Matsuzaki K; Date M; Yoshida K; Furukawa F; Sugano Y; Matsushita M; Himeno Y; Inagaki Y; Inoue K
Hepatology; 2002 Jan; 35(1):49-61. PubMed ID: 11786959
[TBL] [Abstract][Full Text] [Related]
6. Salvianolic acid B exerts anti-liver fibrosis effects via inhibition of MAPK-mediated phospho-Smad2/3 at linker regions in vivo and in vitro.
Wu C; Chen W; Ding H; Li D; Wen G; Zhang C; Lu W; Chen M; Yang Y
Life Sci; 2019 Dec; 239():116881. PubMed ID: 31678285
[TBL] [Abstract][Full Text] [Related]
7. TGF-beta receptor-mediated signalling through Smad2, Smad3 and Smad4.
Nakao A; Imamura T; Souchelnytskyi S; Kawabata M; Ishisaki A; Oeda E; Tamaki K; Hanai J; Heldin CH; Miyazono K; ten Dijke P
EMBO J; 1997 Sep; 16(17):5353-62. PubMed ID: 9311995
[TBL] [Abstract][Full Text] [Related]
8. Smads 2 and 3 are differentially activated by transforming growth factor-beta (TGF-beta ) in quiescent and activated hepatic stellate cells. Constitutive nuclear localization of Smads in activated cells is TGF-beta-independent.
Liu C; Gaça MD; Swenson ES; Vellucci VF; Reiss M; Wells RG
J Biol Chem; 2003 Mar; 278(13):11721-8. PubMed ID: 12547835
[TBL] [Abstract][Full Text] [Related]
9. The transforming growth factor-beta/SMAD signaling pathway is present and functional in human mesangial cells.
Poncelet AC; de Caestecker MP; Schnaper HW
Kidney Int; 1999 Oct; 56(4):1354-65. PubMed ID: 10504488
[TBL] [Abstract][Full Text] [Related]
10. Distortion of autocrine transforming growth factor beta signal accelerates malignant potential by enhancing cell growth as well as PAI-1 and VEGF production in human hepatocellular carcinoma cells.
Sugano Y; Matsuzaki K; Tahashi Y; Furukawa F; Mori S; Yamagata H; Yoshida K; Matsushita M; Nishizawa M; Fujisawa J; Inoue K
Oncogene; 2003 Apr; 22(15):2309-21. PubMed ID: 12700666
[TBL] [Abstract][Full Text] [Related]
11. Transforming growth factor beta signal transduction in hepatic stellate cells via Smad2/3 phosphorylation, a pathway that is abrogated during in vitro progression to myofibroblasts. TGFbeta signal transduction during transdifferentiation of hepatic stellate cells.
Dooley S; Delvoux B; Streckert M; Bonzel L; Stopa M; ten Dijke P; Gressner AM
FEBS Lett; 2001 Jul; 502(1-2):4-10. PubMed ID: 11478938
[TBL] [Abstract][Full Text] [Related]
12. The antifibrotic effects of relaxin in human renal fibroblasts are mediated in part by inhibition of the Smad2 pathway.
Heeg MH; Koziolek MJ; Vasko R; Schaefer L; Sharma K; Müller GA; Strutz F
Kidney Int; 2005 Jul; 68(1):96-109. PubMed ID: 15954899
[TBL] [Abstract][Full Text] [Related]
13. Compound Astragalus and Salvia miltiorrhiza Extract exerts anti-fibrosis by mediating TGF-beta/Smad signaling in myofibroblasts.
Yang Y; Yang S; Chen M; Zhang X; Zou Y; Zhang X
J Ethnopharmacol; 2008 Jul; 118(2):264-70. PubMed ID: 18502066
[TBL] [Abstract][Full Text] [Related]
14. Smad3 mediates transforming growth factor-beta-induced collagenase-3 (matrix metalloproteinase-13) expression in human gingival fibroblasts. Evidence for cross-talk between Smad3 and p38 signaling pathways.
Leivonen SK; Chantry A; Hakkinen L; Han J; Kahari VM
J Biol Chem; 2002 Nov; 277(48):46338-46. PubMed ID: 12270924
[TBL] [Abstract][Full Text] [Related]
15. Role of Rho/ROCK and p38 MAP kinase pathways in transforming growth factor-beta-mediated Smad-dependent growth inhibition of human breast carcinoma cells in vivo.
Kamaraju AK; Roberts AB
J Biol Chem; 2005 Jan; 280(2):1024-36. PubMed ID: 15520018
[TBL] [Abstract][Full Text] [Related]
16. MAPK inhibitors modulate Smad2/3/4 complex cyto-nuclear translocation in myofibroblasts via Imp7/8 mediation.
Jiang Y; Wu C; Boye A; Wu J; Wang J; Yang X; Yang Y
Mol Cell Biochem; 2015 Aug; 406(1-2):255-62. PubMed ID: 25968067
[TBL] [Abstract][Full Text] [Related]
17. Constitutive phosphorylation and nuclear localization of Smad3 are correlated with increased collagen gene transcription in activated hepatic stellate cells.
Inagaki Y; Mamura M; Kanamaru Y; Greenwel P; Nemoto T; Takehara K; Ten Dijke P; Nakao A
J Cell Physiol; 2001 Apr; 187(1):117-23. PubMed ID: 11241356
[TBL] [Abstract][Full Text] [Related]
18. Cell biology of Smad2/3 linker region phosphorylation in vascular smooth muscle.
Rezaei HB; Kamato D; Ansari G; Osman N; Little PJ
Clin Exp Pharmacol Physiol; 2012 Aug; 39(8):661-7. PubMed ID: 21883378
[TBL] [Abstract][Full Text] [Related]
19. Smad2, Smad3 and Smad4 cooperate with Sp1 to induce p15(Ink4B) transcription in response to TGF-beta.
Feng XH; Lin X; Derynck R
EMBO J; 2000 Oct; 19(19):5178-93. PubMed ID: 11013220
[TBL] [Abstract][Full Text] [Related]
20. Inhibition of transforming growth factor (TGF)-beta1-induced extracellular matrix with a novel inhibitor of the TGF-beta type I receptor kinase activity: SB-431542.
Laping NJ; Grygielko E; Mathur A; Butter S; Bomberger J; Tweed C; Martin W; Fornwald J; Lehr R; Harling J; Gaster L; Callahan JF; Olson BA
Mol Pharmacol; 2002 Jul; 62(1):58-64. PubMed ID: 12065755
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
