These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

197 related articles for article (PubMed ID: 14519759)

  • 1. The human dopamine transporter forms a tetramer in the plasma membrane: cross-linking of a cysteine in the fourth transmembrane segment is sensitive to cocaine analogs.
    Hastrup H; Sen N; Javitch JA
    J Biol Chem; 2003 Nov; 278(46):45045-8. PubMed ID: 14519759
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The uptake inhibitors cocaine and benztropine differentially alter the conformation of the human dopamine transporter.
    Reith ME; Berfield JL; Wang LC; Ferrer JV; Javitch JA
    J Biol Chem; 2001 Aug; 276(31):29012-8. PubMed ID: 11395483
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Symmetrical dimer of the human dopamine transporter revealed by cross-linking Cys-306 at the extracellular end of the sixth transmembrane segment.
    Hastrup H; Karlin A; Javitch JA
    Proc Natl Acad Sci U S A; 2001 Aug; 98(18):10055-60. PubMed ID: 11526230
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Recognition of benztropine by the dopamine transporter (DAT) differs from that of the classical dopamine uptake inhibitors cocaine, methylphenidate, and mazindol as a function of a DAT transmembrane 1 aspartic acid residue.
    Ukairo OT; Bondi CD; Newman AH; Kulkarni SS; Kozikowski AP; Pan S; Surratt CK
    J Pharmacol Exp Ther; 2005 Aug; 314(2):575-83. PubMed ID: 15879005
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Dissociation of high-affinity cocaine analog binding and dopamine uptake inhibition at the dopamine transporter.
    Wang W; Sonders MS; Ukairo OT; Scott H; Kloetzel MK; Surratt CK
    Mol Pharmacol; 2003 Aug; 64(2):430-9. PubMed ID: 12869648
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Uptake inhibitors but not substrates induce protease resistance in extracellular loop two of the dopamine transporter.
    Gaffaney JD; Vaughan RA
    Mol Pharmacol; 2004 Mar; 65(3):692-701. PubMed ID: 14978248
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Inhibitor mechanisms in the S1 binding site of the dopamine transporter defined by multi-site molecular tethering of photoactive cocaine analogs.
    Krout D; Pramod AB; Dahal RA; Tomlinson MJ; Sharma B; Foster JD; Zou MF; Boatang C; Newman AH; Lever JR; Vaughan RA; Henry LK
    Biochem Pharmacol; 2017 Oct; 142():204-215. PubMed ID: 28734777
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Identification of intracellular residues in the dopamine transporter critical for regulation of transporter conformation and cocaine binding.
    Loland CJ; Grånäs C; Javitch JA; Gether U
    J Biol Chem; 2004 Jan; 279(5):3228-38. PubMed ID: 14597628
    [TBL] [Abstract][Full Text] [Related]  

  • 9. A pincer-like configuration of TM2 in the human dopamine transporter is responsible for indirect effects on cocaine binding.
    Sen N; Shi L; Beuming T; Weinstein H; Javitch JA
    Neuropharmacology; 2005 Nov; 49(6):780-90. PubMed ID: 16216288
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Evidence for distinct sodium-, dopamine-, and cocaine-dependent conformational changes in transmembrane segments 7 and 8 of the dopamine transporter.
    Norregaard L; Loland CJ; Gether U
    J Biol Chem; 2003 Aug; 278(33):30587-96. PubMed ID: 12773538
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Cocaine induction of dopamine transporter trafficking to the plasma membrane.
    Little KY; Elmer LW; Zhong H; Scheys JO; Zhang L
    Mol Pharmacol; 2002 Feb; 61(2):436-45. PubMed ID: 11809869
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Mutation of Trp84 and Asp313 of the dopamine transporter reveals similar mode of binding interaction for GBR12909 and benztropine as opposed to cocaine.
    Chen N; Zhen J; Reith ME
    J Neurochem; 2004 May; 89(4):853-64. PubMed ID: 15140185
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Dopamine transporter: transmembrane phenylalanine mutations can selectively influence dopamine uptake and cocaine analog recognition.
    Lin Z; Wang W; Kopajtic T; Revay RS; Uhl GR
    Mol Pharmacol; 1999 Aug; 56(2):434-47. PubMed ID: 10419565
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Dopamine transporter proline mutations influence dopamine uptake, cocaine analog recognition, and expression.
    Lin Z; Itokawa M; Uhl GR
    FASEB J; 2000 Apr; 14(5):715-28. PubMed ID: 10744628
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Dopamine transporter tryptophan mutants highlight candidate dopamine- and cocaine-selective domains.
    Lin Z; Wang W; Uhl GR
    Mol Pharmacol; 2000 Dec; 58(6):1581-92. PubMed ID: 11093799
    [TBL] [Abstract][Full Text] [Related]  

  • 16. A triple mutation in the second transmembrane domain of mouse dopamine transporter markedly decreases sensitivity to cocaine and methylphenidate.
    Chen R; Han DD; Gu HH
    J Neurochem; 2005 Jul; 94(2):352-9. PubMed ID: 15998286
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Dopamine transporter transmembrane domain polar mutants: DeltaG and DeltaDeltaG values implicate regions important for transporter functions.
    Itokawa M; Lin Z; Cai NS; Wu C; Kitayama S; Wang JB; Uhl GR
    Mol Pharmacol; 2000 Jun; 57(6):1093-103. PubMed ID: 10825379
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Dopamine transporter cysteine mutants: second extracellular loop cysteines are required for transporter expression.
    Wang JB; Moriwaki A; Uhl GR
    J Neurochem; 1995 Mar; 64(3):1416-9. PubMed ID: 7861176
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Dopamine transporter mutants with cocaine resistance and normal dopamine uptake provide targets for cocaine antagonism.
    Lin Z; Uhl GR
    Mol Pharmacol; 2002 Apr; 61(4):885-91. PubMed ID: 11901228
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Relationship between conformational changes in the dopamine transporter and cocaine-like subjective effects of uptake inhibitors.
    Loland CJ; Desai RI; Zou MF; Cao J; Grundt P; Gerstbrein K; Sitte HH; Newman AH; Katz JL; Gether U
    Mol Pharmacol; 2008 Mar; 73(3):813-23. PubMed ID: 17978168
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.