122 related articles for article (PubMed ID: 14527550)
1. Anti-tumor activity of the farnesyl-protein transferase inhibitors arteminolides, isolated from Artemisa.
Lee SH; Lee MY; Kang HM; Han DC; Son KH; Yang DC; Sung ND; Lee CW; Kim HM; Kwon BM
Bioorg Med Chem; 2003 Oct; 11(21):4545-9. PubMed ID: 14527550
[TBL] [Abstract][Full Text] [Related]
2. Arteminolides B, C, and D, new inhibitors of farnesyl protein transferase from Artemisia argyi.
Lee SH; Kim HK; Seo JM; Kang HM; Kim JH; Son KH; Lee H; Kwon BM; Shin J; Seo Y
J Org Chem; 2002 Nov; 67(22):7670-5. PubMed ID: 12398488
[TBL] [Abstract][Full Text] [Related]
3. Evaluation of farnesyl:protein transferase and geranylgeranyl:protein transferase inhibitor combinations in preclinical models.
Lobell RB; Omer CA; Abrams MT; Bhimnathwala HG; Brucker MJ; Buser CA; Davide JP; deSolms SJ; Dinsmore CJ; Ellis-Hutchings MS; Kral AM; Liu D; Lumma WC; Machotka SV; Rands E; Williams TM; Graham SL; Hartman GD; Oliff AI; Heimbrook DC; Kohl NE
Cancer Res; 2001 Dec; 61(24):8758-68. PubMed ID: 11751396
[TBL] [Abstract][Full Text] [Related]
4. Mouse mammary tumor virus-Ki-rasB transgenic mice develop mammary carcinomas that can be growth-inhibited by a farnesyl:protein transferase inhibitor.
Omer CA; Chen Z; Diehl RE; Conner MW; Chen HY; Trumbauer ME; Gopal-Truter S; Seeburger G; Bhimnathwala H; Abrams MT; Davide JP; Ellis MS; Gibbs JB; Greenberg I; Koblan KS; Kral AM; Liu D; Lobell RB; Miller PJ; Mosser SD; O'Neill TJ; Rands E; Schaber MD; Senderak ET; Oliff A; Kohl NE
Cancer Res; 2000 May; 60(10):2680-8. PubMed ID: 10825141
[TBL] [Abstract][Full Text] [Related]
5. A new class of highly potent farnesyl diphosphate-competitive inhibitors of farnesyltransferase.
Aoyama T; Satoh T; Yonemoto M; Shibata J; Nonoshita K; Arai S; Kawakami K; Iwasawa Y; Sano H; Tanaka K; Monden Y; Kodera T; Arakawa H; Suzuki-Takahashi I; Kamei T; Tomimoto K
J Med Chem; 1998 Jan; 41(2):143-7. PubMed ID: 9457237
[No Abstract] [Full Text] [Related]
6. Farnesyl protein transferase and tumor cell growth inhibitory activities of lipiferolide isolated from Liriodendron tulipifera.
Moon MK; Oh HM; Kwon BM; Baek NI; Kim SH; Kim JS; Kim DK
Arch Pharm Res; 2007 Mar; 30(3):299-302. PubMed ID: 17424934
[TBL] [Abstract][Full Text] [Related]
7. Farnesyltransferase inhibitors versus Ras inhibitors.
Gibbs JB; Graham SL; Hartman GD; Koblan KS; Kohl NE; Omer CA; Oliff A
Curr Opin Chem Biol; 1997 Aug; 1(2):197-203. PubMed ID: 9667853
[TBL] [Abstract][Full Text] [Related]
8. Isolation of farnesyltransferase inhibitors from herbal medicines.
Kwon BM; Lee SH; Kim MJ; Kim HK; Kim HM
Ann N Y Acad Sci; 1999; 886():261-4. PubMed ID: 10667234
[No Abstract] [Full Text] [Related]
9. Inhibitory activity of isorhamnetin from Persicaria thunbergii on Farnesyl Protein Transferase.
Oh HM; Kwon BM; Baek NI; Kim SH; Chung IS; Park MH; Park HW; Lee JH; Park HW; Kim EJ; Kim DK
Arch Pharm Res; 2005 Feb; 28(2):169-71. PubMed ID: 15789745
[TBL] [Abstract][Full Text] [Related]
10. Effects of SCH 59228, an orally bioavailable farnesyl protein transferase inhibitor, on the growth of oncogene-transformed fibroblasts and a human colon carcinoma xenograft in nude mice.
Liu M; Bryant MS; Chen J; Lee S; Yaremko B; Li Z; Dell J; Lipari P; Malkowski M; Prioli N; Rossman RR; Korfmacher WA; Nomeir AA; Lin CC; Mallams AK; Doll RJ; Catino JJ; Girijavallabhan VM; Kirschmeier P; Bishop WR
Cancer Chemother Pharmacol; 1999; 43(1):50-8. PubMed ID: 9923541
[TBL] [Abstract][Full Text] [Related]
11. Two cytotoxic sesquiterpene lactones from the leaves of Xanthium strumarium and their in vitro inhibitory activity on farnesyltransferase.
Kim YS; Kim JS; Park SH; Choi SU; Lee CO; Kim SK; Kim YK; Kim SH; Ryu SY
Planta Med; 2003 Apr; 69(4):375-7. PubMed ID: 12709909
[TBL] [Abstract][Full Text] [Related]
12. Suppression of human pancreatic cancer growth in BALB/c nude mice by manumycin, a farnesyl:protein transferase inhibitor.
Ito T; Kawata S; Tamura S; Igura T; Nagase T; Miyagawa JI; Yamazaki E; Ishiguro H; Matasuzawa Y
Jpn J Cancer Res; 1996 Feb; 87(2):113-6. PubMed ID: 8609057
[TBL] [Abstract][Full Text] [Related]
13. Design and in vivo analysis of potent non-thiol inhibitors of farnesyl protein transferase.
Anthony NJ; Gomez RP; Schaber MD; Mosser SD; Hamilton KA; O'Neil TJ; Koblan KS; Graham SL; Hartman GD; Shah D; Rands E; Kohl NE; Gibbs JB; Oliff AI
J Med Chem; 1999 Aug; 42(17):3356-68. PubMed ID: 10464022
[TBL] [Abstract][Full Text] [Related]
14. Cyclopentenediones, inhibitors of farnesyl protein transferase and anti-tumor compounds, isolated from the fruit of Lindera erythrocarpa Makino.
Oh HM; Choi SK; Lee JM; Lee SK; Kim HY; Han DC; Kim HM; Son KH; Kwon BM
Bioorg Med Chem; 2005 Nov; 13(22):6182-7. PubMed ID: 16055336
[TBL] [Abstract][Full Text] [Related]
15. Clavaric acid and steroidal analogues as Ras- and FPP-directed inhibitors of human farnesyl-protein transferase.
Lingham RB; Silverman KC; Jayasuriya H; Kim BM; Amo SE; Wilson FR; Rew DJ; Schaber MD; Bergstrom JD; Koblan KS; Graham SL; Kohl NE; Gibbs JB; Singh SB
J Med Chem; 1998 Nov; 41(23):4492-501. PubMed ID: 9804689
[TBL] [Abstract][Full Text] [Related]
16. CA1A2X-competitive inhibitors of farnesyltransferase as anti-cancer agents.
Omer CA; Kohl NE
Trends Pharmacol Sci; 1997 Nov; 18(11):437-44. PubMed ID: 9426472
[TBL] [Abstract][Full Text] [Related]
17. Kampanols: novel Ras farnesyl-protein transferase inhibitors from Stachybotrys kampalensis.
Singh SB; Zink DL; Williams M; Polishook JD; Sanchez M; Silverman KC; Lingham RB
Bioorg Med Chem Lett; 1998 Aug; 8(16):2071-6. PubMed ID: 9873488
[TBL] [Abstract][Full Text] [Related]
18. Characterization of the antitumor effects of the selective farnesyl protein transferase inhibitor R115777 in vivo and in vitro.
End DW; Smets G; Todd AV; Applegate TL; Fuery CJ; Angibaud P; Venet M; Sanz G; Poignet H; Skrzat S; Devine A; Wouters W; Bowden C
Cancer Res; 2001 Jan; 61(1):131-7. PubMed ID: 11196150
[TBL] [Abstract][Full Text] [Related]
19. Antitumor activity of orally bioavailable farnesyltransferase inhibitor, ABT-100, is mediated by antiproliferative, proapoptotic, and antiangiogenic effects in xenograft models.
Ferguson D; Rodriguez LE; Palma JP; Refici M; Jarvis K; O'Connor J; Sullivan GM; Frost D; Marsh K; Bauch J; Zhang H; Lin NH; Rosenberg S; Sham HL; Joseph IB
Clin Cancer Res; 2005 Apr; 11(8):3045-54. PubMed ID: 15837760
[TBL] [Abstract][Full Text] [Related]
20. A cell-based radioligand binding assay for farnesyl: protein transferase inhibitors.
Lobell RB; Davide JP; Kohl NE; Burns HD; Eng WS; Gibson RE
J Biomol Screen; 2003 Aug; 8(4):430-8. PubMed ID: 14567795
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]