BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

385 related articles for article (PubMed ID: 14528298)

  • 1. G13 is an essential mediator of platelet activation in hemostasis and thrombosis.
    Moers A; Nieswandt B; Massberg S; Wettschureck N; Grüner S; Konrad I; Schulte V; Aktas B; Gratacap MP; Simon MI; Gawaz M; Offermanns S
    Nat Med; 2003 Nov; 9(11):1418-22. PubMed ID: 14528298
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Anti-glycoprotein VI treatment severely compromises hemostasis in mice with reduced alpha2beta1 levels or concomitant aspirin therapy.
    Grüner S; Prostredna M; Aktas B; Moers A; Schulte V; Krieg T; Offermanns S; Eckes B; Nieswandt B
    Circulation; 2004 Nov; 110(18):2946-51. PubMed ID: 15505105
    [TBL] [Abstract][Full Text] [Related]  

  • 3. G13-mediated signaling as a potential target for antiplatelet drugs.
    Moers A; Wettschureck N; Offermanns S
    Drug News Perspect; 2004 Oct; 17(8):493-8. PubMed ID: 15605108
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Costimulation of Gi- and G12/G13-mediated signaling pathways induces integrin alpha IIbbeta 3 activation in platelets.
    Nieswandt B; Schulte V; Zywietz A; Gratacap MP; Offermanns S
    J Biol Chem; 2002 Oct; 277(42):39493-8. PubMed ID: 12183468
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Activation of platelet function through G protein-coupled receptors.
    Offermanns S
    Circ Res; 2006 Dec; 99(12):1293-304. PubMed ID: 17158345
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Megakaryocyte-specific RhoA deficiency causes macrothrombocytopenia and defective platelet activation in hemostasis and thrombosis.
    Pleines I; Hagedorn I; Gupta S; May F; Chakarova L; van Hengel J; Offermanns S; Krohne G; Kleinschnitz C; Brakebusch C; Nieswandt B
    Blood; 2012 Jan; 119(4):1054-63. PubMed ID: 22045984
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Guanine nucleotide-binding proteins of the G12 family shape immune functions by controlling CD4+ T cell adhesiveness and motility.
    Herroeder S; Reichardt P; Sassmann A; Zimmermann B; Jaeneke D; Hoeckner J; Hollmann MW; Fischer KD; Vogt S; Grosse R; Hogg N; Gunzer M; Offermanns S; Wettschureck N
    Immunity; 2009 May; 30(5):708-20. PubMed ID: 19409815
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Platelets possess and require an active protein palmitoylation pathway for agonist-mediated activation and in vivo thrombus formation.
    Sim DS; Dilks JR; Flaumenhaft R
    Arterioscler Thromb Vasc Biol; 2007 Jun; 27(6):1478-85. PubMed ID: 17303775
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The role of heterotrimeric G proteins in platelet activation.
    Offermanns S
    Biol Chem; 2000; 381(5-6):389-96. PubMed ID: 10937869
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Importance of platelet phospholipase Cgamma2 signaling in arterial thrombosis as a function of lesion severity.
    Nonne C; Lenain N; Hechler B; Mangin P; Cazenave JP; Gachet C; Lanza F
    Arterioscler Thromb Vasc Biol; 2005 Jun; 25(6):1293-8. PubMed ID: 15774906
    [TBL] [Abstract][Full Text] [Related]  

  • 11. PI 3-kinase p110beta: a new target for antithrombotic therapy.
    Jackson SP; Schoenwaelder SM; Goncalves I; Nesbitt WS; Yap CL; Wright CE; Kenche V; Anderson KE; Dopheide SM; Yuan Y; Sturgeon SA; Prabaharan H; Thompson PE; Smith GD; Shepherd PR; Daniele N; Kulkarni S; Abbott B; Saylik D; Jones C; Lu L; Giuliano S; Hughan SC; Angus JA; Robertson AD; Salem HH
    Nat Med; 2005 May; 11(5):507-14. PubMed ID: 15834429
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Platelet chemokines and chemokine receptors: linking hemostasis, inflammation, and host defense.
    Gear AR; Camerini D
    Microcirculation; 2003 Jun; 10(3-4):335-50. PubMed ID: 12851650
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Deficiency or inhibition of Gas6 causes platelet dysfunction and protects mice against thrombosis.
    Angelillo-Scherrer A; de Frutos P; Aparicio C; Melis E; Savi P; Lupu F; Arnout J; Dewerchin M; Hoylaerts M; Herbert J; Collen D; Dahlbäck B; Carmeliet P
    Nat Med; 2001 Feb; 7(2):215-21. PubMed ID: 11175853
    [TBL] [Abstract][Full Text] [Related]  

  • 14. PKCtheta is required for hemostasis and positive regulation of thrombin-induced platelet aggregation and alpha-granule secretion.
    Cohen S; Braiman A; Shubinsky G; Ohayon A; Altman A; Isakov N
    Biochem Biophys Res Commun; 2009 Jul; 385(1):22-7. PubMed ID: 19433059
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Mechanisms of platelet activation: need for new strategies to protect against platelet-mediated atherothrombosis.
    Jennings LK
    Thromb Haemost; 2009 Aug; 102(2):248-57. PubMed ID: 19652875
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Par4 is required for platelet thrombus propagation but not fibrin generation in a mouse model of thrombosis.
    Vandendries ER; Hamilton JR; Coughlin SR; Furie B; Furie BC
    Proc Natl Acad Sci U S A; 2007 Jan; 104(1):288-92. PubMed ID: 17190826
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Characteristic defects in neural crest cell-specific Galphaq/Galpha11- and Galpha12/Galpha13-deficient mice.
    Dettlaff-Swiercz DA; Wettschureck N; Moers A; Huber K; Offermanns S
    Dev Biol; 2005 Jun; 282(1):174-82. PubMed ID: 15936338
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Defective platelet activation in G alpha(q)-deficient mice.
    Offermanns S; Toombs CF; Hu YH; Simon MI
    Nature; 1997 Sep; 389(6647):183-6. PubMed ID: 9296496
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The G protein G alpha(13) is required for growth factor-induced cell migration.
    Shan D; Chen L; Wang D; Tan YC; Gu JL; Huang XY
    Dev Cell; 2006 Jun; 10(6):707-18. PubMed ID: 16740474
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Signaling through G(alpha)13 switch region I is essential for protease-activated receptor 1-mediated human platelet shape change, aggregation, and secretion.
    Huang JS; Dong L; Kozasa T; Le Breton GC
    J Biol Chem; 2007 Apr; 282(14):10210-22. PubMed ID: 17298951
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 20.