These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

171 related articles for article (PubMed ID: 14534298)

  • 1. Beta-arrestin1 mediates insulin-like growth factor 1 (IGF-1) activation of phosphatidylinositol 3-kinase (PI3K) and anti-apoptosis.
    Povsic TJ; Kohout TA; Lefkowitz RJ
    J Biol Chem; 2003 Dec; 278(51):51334-9. PubMed ID: 14534298
    [TBL] [Abstract][Full Text] [Related]  

  • 2. alpha-Thrombin induces rapid and sustained Akt phosphorylation by beta-arrestin1-dependent and -independent mechanisms, and only the sustained Akt phosphorylation is essential for G1 phase progression.
    Goel R; Phillips-Mason PJ; Raben DM; Baldassare JJ
    J Biol Chem; 2002 May; 277(21):18640-8. PubMed ID: 11901145
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Insulin-like growth factor-I inhibits transcriptional responses of transforming growth factor-beta by phosphatidylinositol 3-kinase/Akt-dependent suppression of the activation of Smad3 but not Smad2.
    Song K; Cornelius SC; Reiss M; Danielpour D
    J Biol Chem; 2003 Oct; 278(40):38342-51. PubMed ID: 12876289
    [TBL] [Abstract][Full Text] [Related]  

  • 4. In cardiomyocyte hypoxia, insulin-like growth factor-I-induced antiapoptotic signaling requires phosphatidylinositol-3-OH-kinase-dependent and mitogen-activated protein kinase-dependent activation of the transcription factor cAMP response element-binding protein.
    Mehrhof FB; Müller FU; Bergmann MW; Li P; Wang Y; Schmitz W; Dietz R; von Harsdorf R
    Circulation; 2001 Oct; 104(17):2088-94. PubMed ID: 11673351
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Insulin-induced beta-arrestin1 Ser-412 phosphorylation is a mechanism for desensitization of ERK activation by Galphai-coupled receptors.
    Hupfeld CJ; Resnik JL; Ugi S; Olefsky JM
    J Biol Chem; 2005 Jan; 280(2):1016-23. PubMed ID: 15520010
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Differential regulation of the phosphoinositide 3-kinase and MAP kinase pathways by hepatocyte growth factor vs. insulin-like growth factor-I in myogenic cells.
    Halevy O; Cantley LC
    Exp Cell Res; 2004 Jul; 297(1):224-34. PubMed ID: 15194438
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Insulin-like growth factor I-mediated protection from rapamycin-induced apoptosis is independent of Ras-Erk1-Erk2 and phosphatidylinositol 3'-kinase-Akt signaling pathways.
    Thimmaiah KN; Easton J; Huang S; Veverka KA; Germain GS; Harwood FC; Houghton PJ
    Cancer Res; 2003 Jan; 63(2):364-74. PubMed ID: 12543789
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The luteinizing hormone-releasing hormone inhibits the anti-apoptotic activity of insulin-like growth factor-1 in pituitary alphaT3 cells by protein kinase Calpha-mediated negative regulation of Akt.
    Rose A; Froment P; Perrot V; Quon MJ; LeRoith D; Dupont J
    J Biol Chem; 2004 Dec; 279(50):52500-16. PubMed ID: 15448167
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Insulin-like growth factor-1 regulates endogenous RUNX2 activity in endothelial cells through a phosphatidylinositol 3-kinase/ERK-dependent and Akt-independent signaling pathway.
    Qiao M; Shapiro P; Kumar R; Passaniti A
    J Biol Chem; 2004 Oct; 279(41):42709-18. PubMed ID: 15304489
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Differential insulin-like growth factor I receptor signaling and function in estrogen receptor (ER)-positive MCF-7 and ER-negative MDA-MB-231 breast cancer cells.
    Bartucci M; Morelli C; Mauro L; Andò S; Surmacz E
    Cancer Res; 2001 Sep; 61(18):6747-54. PubMed ID: 11559546
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Interferon-dependent activation of the serine kinase PI 3'-kinase requires engagement of the IRS pathway but not the Stat pathway.
    Uddin S; Majchrzak B; Wang PC; Modi S; Khan MK; Fish EN; Platanias LC
    Biochem Biophys Res Commun; 2000 Apr; 270(1):158-62. PubMed ID: 10733921
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Prevention of cytokine-induced apoptosis by insulin-like growth factor-I is independent of cell adhesion molecules in HT29-D4 colon carcinoma cells-evidence for a NF-kappaB-dependent survival mechanism.
    Garrouste F; Remacle-Bonnet M; Fauriat C; Marvaldi J; Luis J; Pommier G
    Cell Death Differ; 2002 Jul; 9(7):768-79. PubMed ID: 12058282
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Mono- or dual-phosphorylation of akt kinase is regulated by distinct receptors that involve the common insulin receptor substrate.
    Schnyder B; Lahm H; Pittet M; Schnyder-Candrian S
    J Recept Signal Transduct Res; 2002; 22(1-4):213-28. PubMed ID: 12503617
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Phosphatidylinositol 3-kinase (PI-3K)/Akt but not PI-3K/p70 S6 kinase signaling mediates IGF-1-promoted lens epithelial cell survival.
    Chandrasekher G; Sailaja D
    Invest Ophthalmol Vis Sci; 2004 Oct; 45(10):3577-88. PubMed ID: 15452065
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Differential regulation of the phosphatidylinositol 3-kinase/Akt and p70 S6 kinase pathways by the alpha(1A)-adrenergic receptor in rat-1 fibroblasts.
    Ballou LM; Cross ME; Huang S; McReynolds EM; Zhang BX; Lin RZ
    J Biol Chem; 2000 Feb; 275(7):4803-9. PubMed ID: 10671514
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Insulin-like growth factor-I-dependent signal transduction pathways leading to the induction of cell growth and differentiation of human neuroblastoma cell line SH-SY5Y: the roles of MAP kinase pathway and PI 3-kinase pathway.
    Kurihara S; Hakuno F; Takahashi S
    Endocr J; 2000 Dec; 47(6):739-51. PubMed ID: 11228049
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Feedback regulation of beta-arrestin1 function by extracellular signal-regulated kinases.
    Lin FT; Miller WE; Luttrell LM; Lefkowitz RJ
    J Biol Chem; 1999 Jun; 274(23):15971-4. PubMed ID: 10347142
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Regulation of insulin/insulin-like growth factor-1 signaling by proteasome-mediated degradation of insulin receptor substrate-2.
    Rui L; Fisher TL; Thomas J; White MF
    J Biol Chem; 2001 Oct; 276(43):40362-7. PubMed ID: 11546773
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Comparative signaling pathways of insulin-like growth factor-1 and brain-derived neurotrophic factor in hippocampal neurons and the role of the PI3 kinase pathway in cell survival.
    Zheng WH; Quirion R
    J Neurochem; 2004 May; 89(4):844-52. PubMed ID: 15140184
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Overexpression of the Shb SH2 domain-protein in insulin-producing cells leads to altered signaling through the IRS-1 and IRS-2 proteins.
    Welsh N; Makeeva N; Welsh M
    Mol Med; 2002 Nov; 8(11):695-704. PubMed ID: 12520086
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.