BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

189 related articles for article (PubMed ID: 14536079)

  • 1. Bmi-1 regulation of INK4A-ARF is a downstream requirement for transformation of hematopoietic progenitors by E2a-Pbx1.
    Smith KS; Chanda SK; Lingbeek M; Ross DT; Botstein D; van Lohuizen M; Cleary ML
    Mol Cell; 2003 Aug; 12(2):393-400. PubMed ID: 14536079
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Retrovirus-Mediated Expression of E2A-PBX1 Blocks Lymphoid Fate but Permits Retention of Myeloid Potential in Early Hematopoietic Progenitors.
    Woodcroft MW; Nanan K; Thompson P; Tyryshkin K; Smith SP; Slany RK; LeBrun DP
    PLoS One; 2015; 10(6):e0130495. PubMed ID: 26098938
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Chimeric oncoprotein E2a-Pbx1 induces apoptosis of hematopoietic cells by a p53-independent mechanism that is suppressed by Bcl-2.
    Smith KS; Jacobs Y; Chang CP; Cleary ML
    Oncogene; 1997 Jun; 14(24):2917-26. PubMed ID: 9205098
    [TBL] [Abstract][Full Text] [Related]  

  • 4. E2a/Pbx1 induces the rapid proliferation of stem cell factor-dependent murine pro-T cells that cause acute T-lymphoid or myeloid leukemias in mice.
    Sykes DB; Kamps MP
    Mol Cell Biol; 2004 Feb; 24(3):1256-69. PubMed ID: 14729970
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The Hox cooperativity motif of the chimeric oncoprotein E2a-Pbx1 is necessary and sufficient for oncogenesis.
    Chang CP; de Vivo I; Cleary ML
    Mol Cell Biol; 1997 Jan; 17(1):81-8. PubMed ID: 8972188
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Transcriptional profiling during the early differentiation of granulocyte and monocyte progenitors controlled by conditional versions of the E2a-Pbx1 oncoprotein.
    Sykes DB; Scheele J; Pasillas M; Kamps MP
    Leuk Lymphoma; 2003 Jul; 44(7):1187-99. PubMed ID: 12916872
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Bmi-1 collaborates with c-Myc in tumorigenesis by inhibiting c-Myc-induced apoptosis via INK4a/ARF.
    Jacobs JJ; Scheijen B; Voncken JW; Kieboom K; Berns A; van Lohuizen M
    Genes Dev; 1999 Oct; 13(20):2678-90. PubMed ID: 10541554
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Transformation properties of the E2a-Pbx1 chimeric oncoprotein: fusion with E2a is essential, but the Pbx1 homeodomain is dispensable.
    Monica K; LeBrun DP; Dedera DA; Brown R; Cleary ML
    Mol Cell Biol; 1994 Dec; 14(12):8304-14. PubMed ID: 7969166
    [TBL] [Abstract][Full Text] [Related]  

  • 9. A novel zinc finger protein Zfp277 mediates transcriptional repression of the Ink4a/arf locus through polycomb repressive complex 1.
    Negishi M; Saraya A; Mochizuki S; Helin K; Koseki H; Iwama A
    PLoS One; 2010 Aug; 5(8):e12373. PubMed ID: 20808772
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Bmi1 promotes hepatic stem cell expansion and tumorigenicity in both Ink4a/Arf-dependent and -independent manners in mice.
    Chiba T; Seki A; Aoki R; Ichikawa H; Negishi M; Miyagi S; Oguro H; Saraya A; Kamiya A; Nakauchi H; Yokosuka O; Iwama A
    Hepatology; 2010 Sep; 52(3):1111-23. PubMed ID: 20648475
    [TBL] [Abstract][Full Text] [Related]  

  • 11. E2a/Pbx1 oncogene inhibits terminal differentiation but not myeloid potential of pro-T cells.
    Bourette RP; Grasset MF; Mouchiroud G
    Oncogene; 2007 Jan; 26(2):234-47. PubMed ID: 16819510
    [TBL] [Abstract][Full Text] [Related]  

  • 12. [Identification of proteins associated with transcription factors HOXA9 and E2A-PBX1 by tandem affinity purification].
    Shestakova EA; Boutin M; Bourassa S; Bonneil E; Bijl JJ
    Mol Biol (Mosk); 2017; 51(3):490-501. PubMed ID: 28707666
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Bypass of senescence by the polycomb group protein CBX8 through direct binding to the INK4A-ARF locus.
    Dietrich N; Bracken AP; Trinh E; Schjerling CK; Koseki H; Rappsilber J; Helin K; Hansen KH
    EMBO J; 2007 Mar; 26(6):1637-48. PubMed ID: 17332741
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Both Pbx1 and E2A-Pbx1 bind the DNA motif ATCAATCAA cooperatively with the products of multiple murine Hox genes, some of which are themselves oncogenes.
    Lu Q; Knoepfler PS; Scheele J; Wright DD; Kamps MP
    Mol Cell Biol; 1995 Jul; 15(7):3786-95. PubMed ID: 7791786
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Polycomb mediated epigenetic silencing and replication timing at the INK4a/ARF locus during senescence.
    Agherbi H; Gaussmann-Wenger A; Verthuy C; Chasson L; Serrano M; Djabali M
    PLoS One; 2009 May; 4(5):e5622. PubMed ID: 19462008
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Transcriptional coactivator Cited2 induces Bmi1 and Mel18 and controls fibroblast proliferation via Ink4a/ARF.
    Kranc KR; Bamforth SD; Bragança J; Norbury C; van Lohuizen M; Bhattacharya S
    Mol Cell Biol; 2003 Nov; 23(21):7658-66. PubMed ID: 14560011
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The human t(1;19) translocation in pre-B ALL produces multiple nuclear E2A-Pbx1 fusion proteins with differing transforming potentials.
    Kamps MP; Look AT; Baltimore D
    Genes Dev; 1991 Mar; 5(3):358-68. PubMed ID: 1672117
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Contribution of p16(INK4a) to replicative senescence of human fibroblasts.
    Brookes S; Rowe J; Gutierrez Del Arroyo A; Bond J; Peters G
    Exp Cell Res; 2004 Aug; 298(2):549-59. PubMed ID: 15265701
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Transformation of bone marrow B-cell progenitors by E2a-Hlf requires coexpression of Bcl-2.
    Smith KS; Rhee JW; Cleary ML
    Mol Cell Biol; 2002 Nov; 22(21):7678-87. PubMed ID: 12370314
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Heterodimerization of Hox proteins with Pbx1 and oncoprotein E2a-Pbx1 generates unique DNA-binding specifities at nucleotides predicted to contact the N-terminal arm of the Hox homeodomain--demonstration of Hox-dependent targeting of E2a-Pbx1 in vivo.
    Lu Q; Kamps MP
    Oncogene; 1997 Jan; 14(1):75-83. PubMed ID: 9010234
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.