BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

182 related articles for article (PubMed ID: 14563846)

  • 1. Structure of Plasmodium falciparum triose-phosphate isomerase-2-phosphoglycerate complex at 1.1-A resolution.
    Parthasarathy S; Eaazhisai K; Balaram H; Balaram P; Murthy MR
    J Biol Chem; 2003 Dec; 278(52):52461-70. PubMed ID: 14563846
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Structure of the Plasmodium falciparum triosephosphate isomerase-phosphoglycolate complex in two crystal forms: characterization of catalytic loop open and closed conformations in the ligand-bound state.
    Parthasarathy S; Ravindra G; Balaram H; Balaram P; Murthy MR
    Biochemistry; 2002 Nov; 41(44):13178-88. PubMed ID: 12403619
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Structures of Plasmodium falciparum triosephosphate isomerase complexed to substrate analogues: observation of the catalytic loop in the open conformation in the ligand-bound state.
    Parthasarathy S; Balaram H; Balaram P; Murthy MR
    Acta Crystallogr D Biol Crystallogr; 2002 Dec; 58(Pt 12):1992-2000. PubMed ID: 12454456
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Crystal structures of triosephosphate isomerase from methicillin resistant Staphylococcus aureus MRSA252 provide structural insights into novel modes of ligand binding and unique conformations of catalytic loop.
    Mukherjee S; Roychowdhury A; Dutta D; Das AK
    Biochimie; 2012 Dec; 94(12):2532-44. PubMed ID: 22813930
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Crystal structure of triosephosphate isomerase complexed with 2-phosphoglycolate at 0.83-A resolution.
    Kursula I; Wierenga RK
    J Biol Chem; 2003 Mar; 278(11):9544-51. PubMed ID: 12522213
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The adaptability of the active site of trypanosomal triosephosphate isomerase as observed in the crystal structures of three different complexes.
    Noble ME; Wierenga RK; Lambeir AM; Opperdoes FR; Thunnissen AM; Kalk KH; Groendijk H; Hol WG
    Proteins; 1991; 10(1):50-69. PubMed ID: 2062828
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Structures of unliganded and inhibitor complexes of W168F, a Loop6 hinge mutant of Plasmodium falciparum triosephosphate isomerase: observation of an intermediate position of loop6.
    Eaazhisai K; Balaram H; Balaram P; Murthy MR
    J Mol Biol; 2004 Oct; 343(3):671-84. PubMed ID: 15465054
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Biochemical and structural characterization of residue 96 mutants of Plasmodium falciparum triosephosphate isomerase: active-site loop conformation, hydration and identification of a dimer-interface ligand-binding site.
    Gayathri P; Banerjee M; Vijayalakshmi A; Balaram H; Balaram P; Murthy MR
    Acta Crystallogr D Biol Crystallogr; 2009 Aug; 65(Pt 8):847-57. PubMed ID: 19622869
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Closed structure of phosphoglycerate kinase from Thermotoga maritima reveals the catalytic mechanism and determinants of thermal stability.
    Auerbach G; Huber R; Grättinger M; Zaiss K; Schurig H; Jaenicke R; Jacob U
    Structure; 1997 Nov; 5(11):1475-83. PubMed ID: 9384563
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Crystal structure of recombinant human triosephosphate isomerase at 2.8 A resolution. Triosephosphate isomerase-related human genetic disorders and comparison with the trypanosomal enzyme.
    Mande SC; Mainfroid V; Kalk KH; Goraj K; Martial JA; Hol WG
    Protein Sci; 1994 May; 3(5):810-21. PubMed ID: 8061610
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Refined 1.83 A structure of trypanosomal triosephosphate isomerase crystallized in the presence of 2.4 M-ammonium sulphate. A comparison with the structure of the trypanosomal triosephosphate isomerase-glycerol-3-phosphate complex.
    Wierenga RK; Noble ME; Vriend G; Nauche S; Hol WG
    J Mol Biol; 1991 Aug; 220(4):995-1015. PubMed ID: 1880808
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Triose-phosphate isomerase of Leishmania mexicana mexicana. Cloning and characterization of the gene, overexpression in Escherichia coli and analysis of the protein.
    Kohl L; Callens M; Wierenga RK; Opperdoes FR; Michels PA
    Eur J Biochem; 1994 Mar; 220(2):331-8. PubMed ID: 8125090
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Triosephosphate isomerase from Plasmodium falciparum: the crystal structure provides insights into antimalarial drug design.
    Velanker SS; Ray SS; Gokhale RS; Suma S; Balaram H; Balaram P; Murthy MR
    Structure; 1997 Jun; 5(6):751-61. PubMed ID: 9261072
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Solution-state NMR investigations of triosephosphate isomerase active site loop motion: ligand release in relation to active site loop dynamics.
    Rozovsky S; Jogl G; Tong L; McDermott AE
    J Mol Biol; 2001 Jun; 310(1):271-80. PubMed ID: 11419952
    [TBL] [Abstract][Full Text] [Related]  

  • 15. On the three-dimensional structure and catalytic mechanism of triose phosphate isomerase.
    Alber T; Banner DW; Bloomer AC; Petsko GA; Phillips D; Rivers PS; Wilson IA
    Philos Trans R Soc Lond B Biol Sci; 1981 Jun; 293(1063):159-71. PubMed ID: 6115415
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The crystal structure of the "open" and the "closed" conformation of the flexible loop of trypanosomal triosephosphate isomerase.
    Wierenga RK; Noble ME; Postma JP; Groendijk H; Kalk KH; Hol WG; Opperdoes FR
    Proteins; 1991; 10(1):33-49. PubMed ID: 2062827
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Connecting Active-Site Loop Conformations and Catalysis in Triosephosphate Isomerase: Insights from a Rare Variation at Residue 96 in the Plasmodial Enzyme.
    Pareek V; Samanta M; Joshi NV; Balaram H; Murthy MR; Balaram P
    Chembiochem; 2016 Apr; 17(7):620-9. PubMed ID: 26762569
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Structural determinants for ligand binding and catalysis of triosephosphate isomerase.
    Kursula I; Partanen S; Lambeir AM; Antonov DM; Augustyns K; Wierenga RK
    Eur J Biochem; 2001 Oct; 268(19):5189-96. PubMed ID: 11589711
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Crystallographic analysis of the complex between triosephosphate isomerase and 2-phosphoglycolate at 2.5-A resolution: implications for catalysis.
    Lolis E; Petsko GA
    Biochemistry; 1990 Jul; 29(28):6619-25. PubMed ID: 2204418
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Segmental movement: definition of the structural requirements for loop closure in catalysis by triosephosphate isomerase.
    Sampson NS; Knowles JR
    Biochemistry; 1992 Sep; 31(36):8482-7. PubMed ID: 1390632
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.