144 related articles for article (PubMed ID: 14565238)
21. 5-Alkyl-2-alkylamino-6-(2,6-difluorophenylalkyl)-3,4-dihydropyrimidin-4(3H)-ones, a new series of potent, broad-spectrum non-nucleoside reverse transcriptase inhibitors belonging to the DABO family.
Mai A; Artico M; Ragno R; Sbardella G; Massa S; Musiu C; Mura M; Marturana F; Cadeddu A; Maga G; La Colla P
Bioorg Med Chem; 2005 Mar; 13(6):2065-77. PubMed ID: 15727860
[TBL] [Abstract][Full Text] [Related]
22. The role of steric hindrance in 3TC resistance of human immunodeficiency virus type-1 reverse transcriptase.
Gao HQ; Boyer PL; Sarafianos SG; Arnold E; Hughes SH
J Mol Biol; 2000 Jul; 300(2):403-18. PubMed ID: 10873473
[TBL] [Abstract][Full Text] [Related]
23. Synthesis and biological evaluation of 2',3'-didehydro-2',3'- dideoxy-5-fluorocytidine (D4FC) analogues: discovery of carbocyclic nucleoside triphosphates with potent inhibitory activity against HIV-1 reverse transcriptase.
Shi J; McAtee JJ; Schlueter Wirtz S; Tharnish P; Juodawlkis A; Liotta DC; Schinazi RF
J Med Chem; 1999 Mar; 42(5):859-67. PubMed ID: 10072683
[TBL] [Abstract][Full Text] [Related]
24. The design and synthesis of diaryl ether second generation HIV-1 non-nucleoside reverse transcriptase inhibitors (NNRTIs) with enhanced potency versus key clinical mutations.
Tucker TJ; Saggar S; Sisko JT; Tynebor RM; Williams TM; Felock PJ; Flynn JA; Lai MT; Liang Y; McGaughey G; Liu M; Miller M; Moyer G; Munshi V; Perlow-Poehnelt R; Prasad S; Sanchez R; Torrent M; Vacca JP; Wan BL; Yan Y
Bioorg Med Chem Lett; 2008 May; 18(9):2959-66. PubMed ID: 18396399
[TBL] [Abstract][Full Text] [Related]
25. Stereoselective synthesis and antiviral activity of D-2',3'-didehydro-2',3'-dideoxy-2'-fluoro-4'-thionucleosides.
Chong Y; Choo H; Choi Y; Mathew J; Schinazi RF; Chu CK
J Med Chem; 2002 Oct; 45(22):4888-98. PubMed ID: 12383014
[TBL] [Abstract][Full Text] [Related]
26. Parallel one-pot synthesis and structure-activity relationship study of symmetric formimidoester disulfides as a novel class of potent non-nucleoside HIV-1 reverse transcriptase inhibitors.
Cesarini S; Spallarossa A; Ranise A; Schenone S; Bruno O; La Colla P; Casula L; Collu G; Sanna G; Loddo R
Bioorg Med Chem; 2008 Jun; 16(12):6353-63. PubMed ID: 18502646
[TBL] [Abstract][Full Text] [Related]
27. Synthesis, anti-human immunodeficiency virus and anti-hepatitis B virus activities of novel oxaselenolane nucleosides.
Du J; Surzhykov S; Lin JS; Newton MG; Cheng YC; Schinazi RF; Chu CK
J Med Chem; 1997 Sep; 40(19):2991-3. PubMed ID: 9301659
[No Abstract] [Full Text] [Related]
28. Specific targeting highly conserved residues in the HIV-1 reverse transcriptase primer grip region. Design, synthesis, and biological evaluation of novel, potent, and broad spectrum NNRTIs with antiviral activity.
Fattorusso C; Gemma S; Butini S; Huleatt P; Catalanotti B; Persico M; De Angelis M; Fiorini I; Nacci V; Ramunno A; Rodriquez M; Greco G; Novellino E; Bergamini A; Marini S; Coletta M; Maga G; Spadari S; Campiani G
J Med Chem; 2005 Nov; 48(23):7153-65. PubMed ID: 16279773
[TBL] [Abstract][Full Text] [Related]
29. Synthesis and anti-HIV activities of symmetrical dicarboxylate esters of dinucleoside reverse transcriptase inhibitors.
Agarwal HK; Buckheit KW; Buckheit RW; Parang K
Bioorg Med Chem Lett; 2012 Sep; 22(17):5451-4. PubMed ID: 22858097
[TBL] [Abstract][Full Text] [Related]
30. Synthesis and anti-HIV activity of 2'-fluorine modified nucleoside phosphonates: analogs of GS-9148.
Mackman RL; Lin KY; Boojamra CG; Hui H; Douglas J; Grant D; Petrakovsky O; Prasad V; Ray AS; Cihlar T
Bioorg Med Chem Lett; 2008 Feb; 18(3):1116-9. PubMed ID: 18082402
[TBL] [Abstract][Full Text] [Related]
31. Mechanism of antiviral activities of 3'-substituted L-nucleosides against 3TC-resistant HBV polymerase: a molecular modelling approach.
Chong Y; Stuyver L; Otto MJ; Schinazi RF; Chu CK
Antivir Chem Chemother; 2003 Nov; 14(6):309-19. PubMed ID: 14968937
[TBL] [Abstract][Full Text] [Related]
32. Structure-activity relationships of 2'-fluoro-2',3'-unsaturated D-nucleosides as anti-HIV-1 agents.
Lee K; Choi Y; Gumina G; Zhou W; Schinazi RF; Chu CK
J Med Chem; 2002 Mar; 45(6):1313-20. PubMed ID: 11882000
[TBL] [Abstract][Full Text] [Related]
33. Stereoselective synthesis of D- and L-carbocyclic nucleosides by enzymatically catalyzed kinetic resolution.
Mahler M; Reichardt B; Hartjen P; van Lunzen J; Meier C
Chemistry; 2012 Aug; 18(35):11046-62. PubMed ID: 22829408
[TBL] [Abstract][Full Text] [Related]
34. 2-(2,6-Dihalophenyl)-3-(pyrimidin-2-yl)-1,3-thiazolidin-4-ones as non-nucleoside HIV-1 reverse transcriptase inhibitors.
Rao A; Balzarini J; Carbone A; Chimirri A; De Clercq E; Monforte AM; Monforte P; Pannecouque C; Zappalà M
Antiviral Res; 2004 Aug; 63(2):79-84. PubMed ID: 15302136
[TBL] [Abstract][Full Text] [Related]
35. New pyridinone derivatives as potent HIV-1 nonnucleoside reverse transcriptase inhibitors.
Le Van K; Cauvin C; de Walque S; Georges B; Boland S; Martinelli V; Demonté D; Durant F; Hevesi L; Van Lint C
J Med Chem; 2009 Jun; 52(12):3636-43. PubMed ID: 19469474
[TBL] [Abstract][Full Text] [Related]
36. Structure-based design, parallel synthesis, structure-activity relationship, and molecular modeling studies of thiocarbamates, new potent non-nucleoside HIV-1 reverse transcriptase inhibitor isosteres of phenethylthiazolylthiourea derivatives.
Ranise A; Spallarossa A; Cesarini S; Bondavalli F; Schenone S; Bruno O; Menozzi G; Fossa P; Mosti L; La Colla M; Sanna G; Murreddu M; Collu G; Busonera B; Marongiu ME; Pani A; La Colla P; Loddo R
J Med Chem; 2005 Jun; 48(11):3858-73. PubMed ID: 15916438
[TBL] [Abstract][Full Text] [Related]
37. Anti-HIV activity of (-)-(2R,4R)-1- (2-hydroxymethyl-1,3-dioxolan-4-yl)-thymine against drug-resistant HIV-1 mutants and studies of its molecular mechanism.
Chu CK; Yadav V; Chong YH; Schinazi RF
J Med Chem; 2005 Jun; 48(12):3949-52. PubMed ID: 15943470
[TBL] [Abstract][Full Text] [Related]
38. Mutational patterns in the HIV genome and cross-resistance following nucleoside and nucleotide analogue drug exposure.
Miller V; Larder BA
Antivir Ther; 2001; 6 Suppl 3():25-44. PubMed ID: 11678471
[TBL] [Abstract][Full Text] [Related]
39. Discovery of TSAO derivatives with an unusual HIV-1 activity/resistance profile.
de Castro S; García-Aparicio C; Van Laethem K; Gago F; Lobatón E; De Clercq E; Balzarini J; Camarasa MJ; Velázquez S
Antiviral Res; 2006 Aug; 71(1):15-23. PubMed ID: 16616962
[TBL] [Abstract][Full Text] [Related]
40. Synthesis, anti-HIV activity, and resistance profile of thymidine phosphonomethoxy nucleosides and their bis-isopropyloxymethylcarbonyl (bisPOC) prodrugs.
Mackman RL; Zhang L; Prasad V; Boojamra CG; Douglas J; Grant D; Hui H; Kim CU; Laflamme G; Parrish J; Stoycheva AD; Swaminathan S; Wang K; Cihlar T
Bioorg Med Chem; 2007 Aug; 15(16):5519-28. PubMed ID: 17562366
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]