BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

146 related articles for article (PubMed ID: 14565246)

  • 41. Gemcitabine and arabinosylcytosin pharmacogenomics: genome-wide association and drug response biomarkers.
    Li L; Fridley BL; Kalari K; Jenkins G; Batzler A; Weinshilboum RM; Wang L
    PLoS One; 2009 Nov; 4(11):e7765. PubMed ID: 19898621
    [TBL] [Abstract][Full Text] [Related]  

  • 42. Comparison of the cellular pharmacokinetics and toxicity of 2',2'-difluorodeoxycytidine and 1-beta-D-arabinofuranosylcytosine.
    Heinemann V; Hertel LW; Grindey GB; Plunkett W
    Cancer Res; 1988 Jul; 48(14):4024-31. PubMed ID: 3383195
    [TBL] [Abstract][Full Text] [Related]  

  • 43. Inhibition of topoisomerase I cleavage activity by thiol-reactive compounds: importance of vicinal cysteines 504 and 505.
    Montaudon D; Palle K; Rivory LP; Robert J; Douat-Casassus C; Quideau S; Bjornsti MA; Pourquier P
    J Biol Chem; 2007 May; 282(19):14403-12. PubMed ID: 17355975
    [TBL] [Abstract][Full Text] [Related]  

  • 44. Selection of drug-resistant transduced cells with cytosine nucleoside analogs using the human cytidine deaminase gene.
    Beauséjour CM; Eliopoulos N; Momparler L; Le NL; Momparler RL
    Cancer Gene Ther; 2001 Sep; 8(9):669-76. PubMed ID: 11593336
    [TBL] [Abstract][Full Text] [Related]  

  • 45. Comparison of antineoplastic activity of 2',2'-difluorodeoxycytidine and cytosine arabinoside against human myeloid and lymphoid leukemic cells.
    Bouffard DY; Momparler LF; Momparler RL
    Anticancer Drugs; 1991 Feb; 2(1):49-55. PubMed ID: 1958852
    [TBL] [Abstract][Full Text] [Related]  

  • 46. Metabolism of 4'-thio-beta-D-arabinofuranosylcytosine in CEM cells.
    Parker WB; Shaddix SC; Rose LM; Waud WR; Shewach DS; Tiwari KN; Secrist JA
    Biochem Pharmacol; 2000 Dec; 60(12):1925-32. PubMed ID: 11108809
    [TBL] [Abstract][Full Text] [Related]  

  • 47. Apurinic/apyrimidinic endonuclease-1 protein level is associated with the cytotoxicity of L-configuration deoxycytidine analogs (troxacitabine and beta-L-2',3'-dideoxy-2',3'-didehydro-5-fluorocytidine) but not D-configuration deoxycytidine analogs (gemcitabine and beta-D-arabinofuranosylcytosine).
    Lam W; Park SY; Leung CH; Cheng YC
    Mol Pharmacol; 2006 May; 69(5):1607-14. PubMed ID: 16481390
    [TBL] [Abstract][Full Text] [Related]  

  • 48. Differential effects of gemcitabine on ribonucleotide pools of twenty-one solid tumour and leukaemia cell lines.
    van Moorsel CJ; Bergman AM; Veerman G; Voorn DA; Ruiz van Haperen VW; Kroep JR; Pinedo HM; Peters GJ
    Biochim Biophys Acta; 2000 Mar; 1474(1):5-12. PubMed ID: 10699484
    [TBL] [Abstract][Full Text] [Related]  

  • 49. Nucleoside and nucleobase analogs in cancer treatment: not only sapacitabine, but also gemcitabine.
    Muggia F; Diaz I; Peters GJ
    Expert Opin Investig Drugs; 2012 Apr; 21(4):403-8. PubMed ID: 22404148
    [TBL] [Abstract][Full Text] [Related]  

  • 50. Selective targeting of homologous DNA recombination repair by gemcitabine.
    Wachters FM; van Putten JW; Maring JG; Zdzienicka MZ; Groen HJ; Kampinga HH
    Int J Radiat Oncol Biol Phys; 2003 Oct; 57(2):553-62. PubMed ID: 12957269
    [TBL] [Abstract][Full Text] [Related]  

  • 51. Kinetic studies on 2',2'-difluorodeoxycytidine (Gemcitabine) with purified human deoxycytidine kinase and cytidine deaminase.
    Bouffard DY; Laliberté J; Momparler RL
    Biochem Pharmacol; 1993 May; 45(9):1857-61. PubMed ID: 8494545
    [TBL] [Abstract][Full Text] [Related]  

  • 52. DNA recombinase activity of eukaryotic DNA topoisomerase I; effects of camptothecin and other inhibitors.
    Pommier Y; Jenkins J; Kohlhagen G; Leteurtre F
    Mutat Res; 1995 Sep; 337(2):135-45. PubMed ID: 7565862
    [TBL] [Abstract][Full Text] [Related]  

  • 53. Modulatory activity of 2',2'-difluorodeoxycytidine on the phosphorylation and cytotoxicity of arabinosyl nucleosides.
    Gandhi V; Plunkett W
    Cancer Res; 1990 Jun; 50(12):3675-80. PubMed ID: 2340517
    [TBL] [Abstract][Full Text] [Related]  

  • 54. Gemcitabine monotherapy in recurrent ovarian cancer: from the bench to the clinic.
    Bookman MA
    Int J Gynecol Cancer; 2005; 15 Suppl 1():12-7. PubMed ID: 15839953
    [TBL] [Abstract][Full Text] [Related]  

  • 55. DNA cleavage assay for the identification of topoisomerase I inhibitors.
    Dexheimer TS; Pommier Y
    Nat Protoc; 2008; 3(11):1736-50. PubMed ID: 18927559
    [TBL] [Abstract][Full Text] [Related]  

  • 56. Mechanistic studies of the modulation of cleavage activity of topoisomerase I by DNA adducts of mono- and bi-functional PtII complexes.
    Malina J; Vrana O; Brabec V
    Nucleic Acids Res; 2009 Sep; 37(16):5432-42. PubMed ID: 19589806
    [TBL] [Abstract][Full Text] [Related]  

  • 57. Quantification of gemcitabine incorporation into human DNA by LC/MS/MS as a surrogate measure for target engagement.
    Wickremsinhe ER; Lutzke BS; Jones BR; Schultz GA; Freeman AB; Pratt SE; Bones AM; Ackermann BL
    Anal Chem; 2010 Aug; 82(15):6576-83. PubMed ID: 20698580
    [TBL] [Abstract][Full Text] [Related]  

  • 58. Nucleoside analogues: mechanisms of drug resistance and reversal strategies.
    Galmarini CM; Mackey JR; Dumontet C
    Leukemia; 2001 Jun; 15(6):875-90. PubMed ID: 11417472
    [TBL] [Abstract][Full Text] [Related]  

  • 59. Synthesis and restriction enzyme analysis of oligodeoxyribonucleotides containing the anti-cancer drug 2',2'-difluoro-2'-deoxycytidine.
    Richardson FC; Richardson KK; Kroin JS; Hertel LW
    Nucleic Acids Res; 1992 Apr; 20(7):1763-8. PubMed ID: 1579470
    [TBL] [Abstract][Full Text] [Related]  

  • 60. Antitumor activity of sugar-modified cytosine nucleosides.
    Matsuda A; Sasaki T
    Cancer Sci; 2004 Feb; 95(2):105-11. PubMed ID: 14965358
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 8.