These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

120 related articles for article (PubMed ID: 14565282)

  • 1. Design of Mycobacterium tuberculosis thymidine monophosphate kinase inhibitors.
    Munier-Lehmann H; Pochet S; Dugue L; Dutruel O; Labesse G; Douget D
    Nucleosides Nucleotides Nucleic Acids; 2003; 22(5-8):801-4. PubMed ID: 14565282
    [No Abstract]   [Full Text] [Related]  

  • 2. A new family of inhibitors of Mycobacterium tuberculosis thymidine monophosphate kinase.
    Gasse C; Huteau V; Douguet D; Munier-Lehmann H; Pochet S
    Nucleosides Nucleotides Nucleic Acids; 2007; 26(8-9):1057-61. PubMed ID: 18058536
    [No Abstract]   [Full Text] [Related]  

  • 3. Discovery of bicyclic thymidine analogues as selective and high-affinity inhibitors of Mycobacterium tuberculosis thymidine monophosphate kinase.
    Vanheusden V; Munier-Lehmann H; Froeyen M; Busson R; Rozenski J; Herdewijn P; Van Calenbergh S
    J Med Chem; 2004 Dec; 47(25):6187-94. PubMed ID: 15566289
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Thymidine and thymidine-5'-O-monophosphate analogues as inhibitors of Mycobacterium tuberculosis thymidylate kinase.
    Vanheusden V; Van Rompaey P; Munier-Lehmann H; Pochet S; Herdewijn P; Van Calenbergh S
    Bioorg Med Chem Lett; 2003 Sep; 13(18):3045-8. PubMed ID: 12941330
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Rational design and 3D-pharmacophore mapping of 5'-thiourea-substituted alpha-thymidine analogues as mycobacterial TMPK inhibitors.
    Andrade CH; Pasqualoto KF; Ferreira EI; Hopfinger AJ
    J Chem Inf Model; 2009 Apr; 49(4):1070-8. PubMed ID: 19296716
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Exploring acyclic nucleoside analogues as inhibitors of Mycobacterium tuberculosis thymidylate kinase.
    Familiar O; Munier-Lehmann H; Negri A; Gago F; Douguet D; Rigouts L; Hernández AI; Camarasa MJ; Pérez-Pérez MJ
    ChemMedChem; 2008 Jul; 3(7):1083-93. PubMed ID: 18418833
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Synthesis and evaluation of thymidine-5'-O-monophosphate analogues as inhibitors of Mycobacterium tuberculosis thymidylate kinase.
    Vanheusden V; Munier-Lehmann H; Pochet S; Herdewijn P; Van Calenbergh S
    Bioorg Med Chem Lett; 2002 Oct; 12(19):2695-8. PubMed ID: 12217356
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Synthesis and inhibitory activity of thymidine analogues targeting Mycobacterium tuberculosis thymidine monophosphate kinase.
    Van Poecke S; Munier-Lehmann H; Helynck O; Froeyen M; Van Calenbergh S
    Bioorg Med Chem; 2011 Dec; 19(24):7603-11. PubMed ID: 22061826
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Synthesis and evaluation of 5'-modified thymidines and 5-hydroxymethyl-2'-deoxyuridines as Mycobacterium tuberculosis thymidylate kinase inhibitors.
    Toti KS; Verbeke F; Risseeuw MD; Frecer V; Munier-Lehmann H; Van Calenbergh S
    Bioorg Med Chem; 2013 Jan; 21(1):257-68. PubMed ID: 23199481
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Structure-aided design of inhibitors of Mycobacterium tuberculosis thymidylate kinase.
    Van Calenbergh S
    Verh K Acad Geneeskd Belg; 2006; 68(4):223-48. PubMed ID: 17214439
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Substituted benzyl-pyrimidines targeting thymidine monophosphate kinase of Mycobacterium tuberculosis: synthesis and in vitro anti-mycobacterial activity.
    Gasse C; Douguet D; Huteau V; Marchal G; Munier-Lehmann H; Pochet S
    Bioorg Med Chem; 2008 Jun; 16(11):6075-85. PubMed ID: 18467107
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Drug design and identification of potent leads against mycobacterium tuberculosis thymidine monophosphate kinase.
    Van Calenbergh S; Pochet S; Munier-Lehmann H
    Curr Top Med Chem; 2012; 12(7):694-705. PubMed ID: 22283813
    [TBL] [Abstract][Full Text] [Related]  

  • 13. 3'-C-branched-chain-substituted nucleosides and nucleotides as potent inhibitors of Mycobacterium tuberculosis thymidine monophosphate kinase.
    Vanheusden V; Munier-Lehmann H; Froeyen M; Dugué L; Heyerick A; De Keukeleire D; Pochet S; Busson R; Herdewijn P; Van Calenbergh S
    J Med Chem; 2003 Aug; 46(18):3811-21. PubMed ID: 12930144
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Synthesis and biological evaluation of inhibitors of thymidine monophosphate kinase from Bacillus anthracis.
    Byun Y; Vogel SR; Phipps AJ; Carnrot C; Eriksson S; Tiwari R; Tjarks W
    Nucleosides Nucleotides Nucleic Acids; 2008 Mar; 27(3):244-60. PubMed ID: 18260009
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Rational design of 5'-thiourea-substituted alpha-thymidine analogues as thymidine monophosphate kinase inhibitors capable of inhibiting mycobacterial growth.
    Van Daele I; Munier-Lehmann H; Froeyen M; Balzarini J; Van Calenbergh S
    J Med Chem; 2007 Nov; 50(22):5281-92. PubMed ID: 17910427
    [TBL] [Abstract][Full Text] [Related]  

  • 16. 3D-QSAR studies on antitubercular thymidine monophosphate kinase inhibitors based on different alignment methods.
    Aparna V; Jeevan J; Ravi M; Desiraju GR; Gopalakrishnan B
    Bioorg Med Chem Lett; 2006 Feb; 16(4):1014-20. PubMed ID: 16290929
    [TBL] [Abstract][Full Text] [Related]  

  • 17. A virtual screening approach for thymidine monophosphate kinase inhibitors as antitubercular agents based on docking and pharmacophore models.
    Gopalakrishnan B; Aparna V; Jeevan J; Ravi M; Desiraju GR
    J Chem Inf Model; 2005; 45(4):1101-8. PubMed ID: 16045305
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Design, synthesis and inhibitory activity against Mycobacterium tuberculosis thymidine monophosphate kinase of acyclic nucleoside analogues with a distal imidazoquinolinone.
    Familiar O; Munier-Lehmann H; Aínsa JA; Camarasa MJ; Pérez-Pérez MJ
    Eur J Med Chem; 2010 Dec; 45(12):5910-8. PubMed ID: 20951473
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Comparative study of purine and pyrimidine nucleoside analogues acting on the thymidylate kinases of Mycobacterium tuberculosis and of humans.
    Pochet S; Dugué L; Labesse G; Delepierre M; Munier-Lehmann H
    Chembiochem; 2003 Aug; 4(8):742-7. PubMed ID: 12898625
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Computer-assisted combinatorial design of bicyclic thymidine analogs as inhibitors of Mycobacterium tuberculosis thymidine monophosphate kinase.
    Frecer V; Seneci P; Miertus S
    J Comput Aided Mol Des; 2011 Jan; 25(1):31-49. PubMed ID: 21082329
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.