BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

136 related articles for article (PubMed ID: 14565497)

  • 1. Structural characterization of LNA and alpha-L-LNA hybridized to RNA.
    Petersen M; Nielsen JT; Bondensgaard K; Wengel J; Jacobsen JP
    Nucleosides Nucleotides Nucleic Acids; 2003; 22(5-8):1691-3. PubMed ID: 14565497
    [TBL] [Abstract][Full Text] [Related]  

  • 2. NMR studies of fully modified locked nucleic acid (LNA) hybrids: solution structure of an LNA:RNA hybrid and characterization of an LNA:DNA hybrid.
    Nielsen KE; Rasmussen J; Kumar R; Wengel J; Jacobsen JP; Petersen M
    Bioconjug Chem; 2004; 15(3):449-57. PubMed ID: 15149171
    [TBL] [Abstract][Full Text] [Related]  

  • 3. LNA and alpha-L-LNA: towards therapeutic applications.
    Wengel J; Vester B; Lundberg LB; Douthwaite S; Sørensen MD; Babu BR; Gait MJ; Arzumanov A; Petersen M; Nielsen JT
    Nucleosides Nucleotides Nucleic Acids; 2003; 22(5-8):601-4. PubMed ID: 14565236
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Parallel nucleic acid recognition by the LNA (locked nucleic acid) stereoisomers beta-L-LNA and alpha-D-LNA; studies in the mirror image world.
    Christensen NK; Bryld T; Sørensen MD; Arar K; Wengel J; Nielsen P
    Chem Commun (Camb); 2004 Feb; (3):282-3. PubMed ID: 14740038
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Alpha-LNA (alpha-D-configured locked nucleic acid).
    Christensen NK; Petersen M; Vester B; Nielsen P
    Nucleosides Nucleotides Nucleic Acids; 2003; 22(5-8):1143-5. PubMed ID: 14565365
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The structure of a mixed LNA/DNA:RNA duplex is driven by conformational coupling between LNA and deoxyribose residues as determined from 13C relaxation measurements.
    Nielsen KE; Spielmann HP
    J Am Chem Soc; 2005 Nov; 127(43):15273-82. PubMed ID: 16248670
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Synthesis, nucleic acid hybridization properties and molecular modelling studies of conformationally restricted 3'-O,4'-C-methylene-linked alpha-L-ribonucleotides.
    Madsen AS; Hrdlicka PJ; Kumar TS; Wengel J
    Carbohydr Res; 2006 Jul; 341(10):1398-407. PubMed ID: 16709404
    [TBL] [Abstract][Full Text] [Related]  

  • 8. On the in vitro and in vivo properties of four locked nucleic acid nucleotides incorporated into an anti-H-Ras antisense oligonucleotide.
    Fluiter K; Frieden M; Vreijling J; Rosenbohm C; De Wissel MB; Christensen SM; Koch T; Ørum H; Baas F
    Chembiochem; 2005 Jun; 6(6):1104-9. PubMed ID: 15861430
    [TBL] [Abstract][Full Text] [Related]  

  • 9. LNA (locked nucleic acid): high-affinity targeting of complementary RNA and DNA.
    Vester B; Wengel J
    Biochemistry; 2004 Oct; 43(42):13233-41. PubMed ID: 15491130
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Free-radical ring closure to conformationally locked α-L-carba-LNAs and synthesis of their oligos: nuclease stability, target RNA specificity, and elicitation of RNase H.
    Li Q; Yuan F; Zhou C; Plashkevych O; Chattopadhyaya J
    J Org Chem; 2010 Sep; 75(18):6122-40. PubMed ID: 20738147
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Aryl-beta-C-LNA monomers as universal hybridization probes.
    Babu BR; Wengel J
    Nucleosides Nucleotides Nucleic Acids; 2003; 22(5-8):1317-9. PubMed ID: 14565408
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Synthesis and structural characterization of 2'-fluoro-α-L-RNA-modified oligonucleotides.
    Bundgaard Jensen T; Pasternak A; Stahl Madsen A; Petersen M; Wengel J
    Chembiochem; 2011 Aug; 12(12):1904-11. PubMed ID: 21728225
    [TBL] [Abstract][Full Text] [Related]  

  • 13. LNA (locked nucleic acid) and the diastereoisomeric alpha-L-LNA: conformational tuning and high-affinity recognition of DNA/RNA targets.
    Wengel J; Petersen M; Nielsen KE; Jensen GA; Håkansson AE; Kumar R; Sørensen MD; Rajwanshi VK; Bryld T; Jacobsen JP
    Nucleosides Nucleotides Nucleic Acids; 2001; 20(4-7):389-96. PubMed ID: 11563053
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Locked nucleic acids: a promising molecular family for gene-function analysis and antisense drug development.
    Orum H; Wengel J
    Curr Opin Mol Ther; 2001 Jun; 3(3):239-43. PubMed ID: 11497347
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Double sugar and phosphate backbone-constrained nucleotides: synthesis, structure, stability, and their incorporation into oligodeoxynucleotides.
    Zhou C; Plashkevych O; Chattopadhyaya J
    J Org Chem; 2009 May; 74(9):3248-65. PubMed ID: 19348480
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Conformationally controlled high-affinity targeting of RNA or DNA by novel 2'-amino-DNA/LNA mixmers and pyrenyl-functionalized 2'-amino-DNA.
    Kalra N; Babu BR; Parmar VS; Wengel J
    Org Biomol Chem; 2004 Oct; 2(20):2885-7. PubMed ID: 15480448
    [TBL] [Abstract][Full Text] [Related]  

  • 17. [Progress in locked nucleic acid research].
    Li SM; Xu X; Liang HP; Li L
    Sheng Li Ke Xue Jin Zhan; 2003 Oct; 34(4):319-23. PubMed ID: 14992013
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Effect of LNA modifications on small molecule binding to nucleic acids.
    Marin V; Hansen HF; Koch T; Armitage BA
    J Biomol Struct Dyn; 2004 Jun; 21(6):841-50. PubMed ID: 15107006
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Nuclease resistant methylphosphonate-DNA/LNA chimeric oligonucleotides.
    Nagahama K; Veedu RN; Wengel J
    Bioorg Med Chem Lett; 2009 May; 19(10):2707-9. PubMed ID: 19375912
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Locked nucleic acid oligonucleotides: the next generation of antisense agents?
    Grünweller A; Hartmann RK
    BioDrugs; 2007; 21(4):235-43. PubMed ID: 17628121
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.