BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

159 related articles for article (PubMed ID: 14570776)

  • 1. Identification of zomepirac-S-acyl-glutathione in vitro in incubations with rat hepatocytes and in vivo in rat bile.
    Grillo MP; Hua F
    Drug Metab Dispos; 2003 Nov; 31(11):1429-36. PubMed ID: 14570776
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Mechanistic studies on the bioactivation of diclofenac: identification of diclofenac-S-acyl-glutathione in vitro in incubations with rat and human hepatocytes.
    Grillo MP; Hua F; Knutson CG; Ware JA; Li C
    Chem Res Toxicol; 2003 Nov; 16(11):1410-7. PubMed ID: 14615966
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Enantioselective formation of ibuprofen-S-acyl-glutathione in vitro in incubations of ibuprofen with rat hepatocytes.
    Grillo MP; Hua F
    Chem Res Toxicol; 2008 Sep; 21(9):1749-59. PubMed ID: 18680316
    [TBL] [Abstract][Full Text] [Related]  

  • 4. In vitro and in vivo studies on acyl-coenzyme A-dependent bioactivation of zomepirac in rats.
    Olsen J; Li C; Bjørnsdottir I; Sidenius U; Hansen SH; Benet LZ
    Chem Res Toxicol; 2005 Nov; 18(11):1729-36. PubMed ID: 16300382
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Metabolic activation of mefenamic acid leading to mefenamyl-S-acyl-glutathione adduct formation in vitro and in vivo in rat.
    Grillo MP; Tadano Lohr M; Wait JC
    Drug Metab Dispos; 2012 Aug; 40(8):1515-26. PubMed ID: 22577085
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Gamma-glutamyltranspeptidase-mediated degradation of diclofenac-S-acyl-glutathione in vitro and in vivo in rat.
    Grillo MP; Hua F; March KL; Benet LZ; Knutson CG; Ware JA
    Chem Res Toxicol; 2008 Oct; 21(10):1933-8. PubMed ID: 18693772
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Evidence for the bioactivation of zomepirac and tolmetin by an oxidative pathway: identification of glutathione adducts in vitro in human liver microsomes and in vivo in rats.
    Chen Q; Doss GA; Tung EC; Liu W; Tang YS; Braun MP; Didolkar V; Strauss JR; Wang RW; Stearns RA; Evans DC; Baillie TA; Tang W
    Drug Metab Dispos; 2006 Jan; 34(1):145-51. PubMed ID: 16251255
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Studies on the chemical reactivity of diclofenac acyl glucuronide with glutathione: identification of diclofenac-S-acyl-glutathione in rat bile.
    Grillo MP; Knutson CG; Sanders PE; Waldon DJ; Hua F; Ware JA
    Drug Metab Dispos; 2003 Nov; 31(11):1327-36. PubMed ID: 14570764
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Studies on the metabolism of tolmetin to the chemically reactive acyl-coenzyme A thioester intermediate in rats.
    Olsen J; Li C; Skonberg C; Bjørnsdottir I; Sidenius U; Benet LZ; Hansen SH
    Drug Metab Dispos; 2007 May; 35(5):758-64. PubMed ID: 17303625
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Characterization and formation of the glutathione conjugate of clofibric acid.
    Shore LJ; Fenselau C; King AR; Dickinson RG
    Drug Metab Dispos; 1995 Jan; 23(1):119-23. PubMed ID: 7720514
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Stereoselective flunoxaprofen-S-acyl-glutathione thioester formation mediated by acyl-CoA formation in rat hepatocytes.
    Grillo MP; Wait JC; Tadano Lohr M; Khera S; Benet LZ
    Drug Metab Dispos; 2010 Jan; 38(1):133-42. PubMed ID: 19786506
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Formation and biliary excretion of glutathione conjugates of bile acids in the rat as shown by liquid chromatography/electrospray ionization-linear ion trap mass spectrometry.
    Mitamura K; Watanabe S; Mitsumoto Y; Sakai T; Sogabe M; Wakamiya T; Ikegawa S
    Anal Biochem; 2009 Jan; 384(2):224-30. PubMed ID: 18938128
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Identification in rat bile of glutathione conjugates of fluoromethyl 2,2-difluoro-1-(trifluoromethyl)vinyl ether, a nephrotoxic degradate of the anesthetic agent sevoflurane.
    Jin L; Davis MR; Kharasch ED; Doss GA; Baillie TA
    Chem Res Toxicol; 1996 Mar; 9(2):555-61. PubMed ID: 8839062
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Chemical and immunochemical comparison of protein adduct formation of four carboxylate drugs in rat liver and plasma.
    Bailey MJ; Dickinson RG
    Chem Res Toxicol; 1996; 9(3):659-66. PubMed ID: 8728513
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Studies on cytochrome P-450-mediated bioactivation of diclofenac in rats and in human hepatocytes: identification of glutathione conjugated metabolites.
    Tang W; Stearns RA; Bandiera SM; Zhang Y; Raab C; Braun MP; Dean DC; Pang J; Leung KH; Doss GA; Strauss JR; Kwei GY; Rushmore TH; Chiu SH; Baillie TA
    Drug Metab Dispos; 1999 Mar; 27(3):365-72. PubMed ID: 10064567
    [TBL] [Abstract][Full Text] [Related]  

  • 16. A novel bioactivation pathway for 2-[2-(2,6-dichlorophenyl)aminophenyl]ethanoic acid (diclofenac) initiated by cytochrome P450-mediated oxidative decarboxylation.
    Grillo MP; Ma J; Teffera Y; Waldon DJ
    Drug Metab Dispos; 2008 Sep; 36(9):1740-4. PubMed ID: 18541695
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Identification of bile acid S-acyl glutathione conjugates in rat bile by liquid chromatography/electrospray ionization-linear ion trap mass spectrometry.
    Mitamura K; Hori N; Iida T; Hofmann AF; Ikegawa S
    Steroids; 2011 Jan; 76(1-2):68-77. PubMed ID: 20837038
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Interaction of γ-glutamyltranspeptidase with ibuprofen-S-acyl-glutathione in vitro and in vivo in human.
    Grillo MP; Lohr MT; Khera S
    Drug Metab Dispos; 2013 Jan; 41(1):111-21. PubMed ID: 23052971
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Determination of degradation pathways and kinetics of acyl glucuronides by NMR spectroscopy.
    Walker GS; Atherton J; Bauman J; Kohl C; Lam W; Reily M; Lou Z; Mutlib A
    Chem Res Toxicol; 2007 Jun; 20(6):876-86. PubMed ID: 17536843
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Interaction of gamma-glutamyltranspeptidase with clofibryl-S-acyl-glutathione in vitro and in vivo in rat.
    Grillo MP; Benet LZ
    Chem Res Toxicol; 2001 Aug; 14(8):1033-40. PubMed ID: 11511177
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.