BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

161 related articles for article (PubMed ID: 14575301)

  • 1. A mouse model of familial hypertrophic cardiomyopathy caused by a alpha-tropomyosin mutation.
    Prabhakar R; Petrashevskaya N; Schwartz A; Aronow B; Boivin GP; Molkentin JD; Wieczorek DF
    Mol Cell Biochem; 2003 Sep; 251(1-2):33-42. PubMed ID: 14575301
    [TBL] [Abstract][Full Text] [Related]  

  • 2. A familial hypertrophic cardiomyopathy alpha-tropomyosin mutation causes severe cardiac hypertrophy and death in mice.
    Prabhakar R; Boivin GP; Grupp IL; Hoit B; Arteaga G; Solaro RJ; Wieczorek DF
    J Mol Cell Cardiol; 2001 Oct; 33(10):1815-28. PubMed ID: 11603924
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Rescue of tropomyosin-induced familial hypertrophic cardiomyopathy mice by transgenesis.
    Jagatheesan G; Rajan S; Petrashevskaya N; Schwartz A; Boivin G; Arteaga GM; Solaro RJ; Liggett SB; Wieczorek DF
    Am J Physiol Heart Circ Physiol; 2007 Aug; 293(2):H949-58. PubMed ID: 17416600
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Dilated cardiomyopathy mutant tropomyosin mice develop cardiac dysfunction with significantly decreased fractional shortening and myofilament calcium sensitivity.
    Rajan S; Ahmed RP; Jagatheesan G; Petrashevskaya N; Boivin GP; Urboniene D; Arteaga GM; Wolska BM; Solaro RJ; Liggett SB; Wieczorek DF
    Circ Res; 2007 Jul; 101(2):205-14. PubMed ID: 17556658
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Hypertrophy, fibrosis, and sudden cardiac death in response to pathological stimuli in mice with mutations in cardiac troponin T.
    Maass AH; Ikeda K; Oberdorf-Maass S; Maier SK; Leinwand LA
    Circulation; 2004 Oct; 110(15):2102-9. PubMed ID: 15466629
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Long-term rescue of a familial hypertrophic cardiomyopathy caused by a mutation in the thin filament protein, tropomyosin, via modulation of a calcium cycling protein.
    Gaffin RD; Peña JR; Alves MS; Dias FA; Chowdhury SA; Heinrich LS; Goldspink PH; Kranias EG; Wieczorek DF; Wolska BM
    J Mol Cell Cardiol; 2011 Nov; 51(5):812-20. PubMed ID: 21840315
    [TBL] [Abstract][Full Text] [Related]  

  • 7. alpha-Tropomyosin mutations Asp(175)Asn and Glu(180)Gly affect cardiac function in transgenic rats in different ways.
    Wernicke D; Thiel C; Duja-Isac CM; Essin KV; Spindler M; Nunez DJ; Plehm R; Wessel N; Hammes A; Edwards RJ; Lippoldt A; Zacharias U; Strömer H; Neubauer S; Davies MJ; Morano I; Thierfelder L
    Am J Physiol Regul Integr Comp Physiol; 2004 Sep; 287(3):R685-95. PubMed ID: 15031138
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Familial hypertrophic cardiomyopathy-linked mutant troponin T causes stress-induced ventricular tachycardia and Ca2+-dependent action potential remodeling.
    Knollmann BC; Kirchhof P; Sirenko SG; Degen H; Greene AE; Schober T; Mackow JC; Fabritz L; Potter JD; Morad M
    Circ Res; 2003 Mar; 92(4):428-36. PubMed ID: 12600890
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Novel troponin T mutation in familial dilated cardiomyopathy with gender-dependant severity.
    Stefanelli CB; Rosenthal A; Borisov AB; Ensing GJ; Russell MW
    Mol Genet Metab; 2004; 83(1-2):188-96. PubMed ID: 15464434
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Microarray analysis of active cardiac remodeling genes in a familial hypertrophic cardiomyopathy mouse model rescued by a phospholamban knockout.
    Rajan S; Pena JR; Jegga AG; Aronow BJ; Wolska BM; Wieczorek DF
    Physiol Genomics; 2013 Sep; 45(17):764-73. PubMed ID: 23800848
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Altered signaling surrounding the C-lobe of cardiac troponin C in myofilaments containing an alpha-tropomyosin mutation linked to familial hypertrophic cardiomyopathy.
    Burkart EM; Arteaga GM; Sumandea MP; Prabhakar R; Wieczorek DF; Solaro RJ
    J Mol Cell Cardiol; 2003 Oct; 35(10):1285-93. PubMed ID: 14519438
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Microarray analysis of gene expression during early stages of mild and severe cardiac hypertrophy.
    Rajan S; Williams SS; Jagatheesan G; Ahmed RP; Fuller-Bicer G; Schwartz A; Aronow BJ; Wieczorek DF
    Physiol Genomics; 2006 Nov; 27(3):309-17. PubMed ID: 16882888
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Cellular and molecular aspects of familial hypertrophic cardiomyopathy caused by mutations in the cardiac troponin I gene.
    Gomes AV; Potter JD
    Mol Cell Biochem; 2004 Aug; 263(1-2):99-114. PubMed ID: 15524171
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Clinically Divergent Mutation Effects on the Structure and Function of the Human Cardiac Tropomyosin Overlap.
    McConnell M; Tal Grinspan L; Williams MR; Lynn ML; Schwartz BA; Fass OZ; Schwartz SD; Tardiff JC
    Biochemistry; 2017 Jul; 56(26):3403-3413. PubMed ID: 28603979
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Molecular insights from a novel cardiac troponin I mouse model of familial hypertrophic cardiomyopathy.
    Tsoutsman T; Chung J; Doolan A; Nguyen L; Williams IA; Tu E; Lam L; Bailey CG; Rasko JE; Allen DG; Semsarian C
    J Mol Cell Cardiol; 2006 Oct; 41(4):623-32. PubMed ID: 16950368
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Mutations in the genes for cardiac troponin T and alpha-tropomyosin in hypertrophic cardiomyopathy.
    Watkins H; McKenna WJ; Thierfelder L; Suk HJ; Anan R; O'Donoghue A; Spirito P; Matsumori A; Moravec CS; Seidman JG
    N Engl J Med; 1995 Apr; 332(16):1058-64. PubMed ID: 7898523
    [TBL] [Abstract][Full Text] [Related]  

  • 17. An internal domain of beta-tropomyosin increases myofilament Ca(2+) sensitivity.
    Jagatheesan G; Rajan S; Schulz EM; Ahmed RP; Petrashevskaya N; Schwartz A; Boivin GP; Arteaga GM; Wang T; Wang YG; Ashraf M; Liggett SB; Lorenz J; Solaro RJ; Wieczorek DF
    Am J Physiol Heart Circ Physiol; 2009 Jul; 297(1):H181-90. PubMed ID: 19429821
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Severe heart failure and early mortality in a double-mutation mouse model of familial hypertrophic cardiomyopathy.
    Tsoutsman T; Kelly M; Ng DC; Tan JE; Tu E; Lam L; Bogoyevitch MA; Seidman CE; Seidman JG; Semsarian C
    Circulation; 2008 Apr; 117(14):1820-31. PubMed ID: 18362229
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The E22K mutation of myosin RLC that causes familial hypertrophic cardiomyopathy increases calcium sensitivity of force and ATPase in transgenic mice.
    Szczesna-Cordary D; Guzman G; Zhao J; Hernandez O; Wei J; Diaz-Perez Z
    J Cell Sci; 2005 Aug; 118(Pt 16):3675-83. PubMed ID: 16076902
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Direct, convergent hypersensitivity of calcium-activated force generation produced by hypertrophic cardiomyopathy mutant alpha-tropomyosins in adult cardiac myocytes.
    Michele DE; Albayya FP; Metzger JM
    Nat Med; 1999 Dec; 5(12):1413-7. PubMed ID: 10581085
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.