BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

762 related articles for article (PubMed ID: 14580334)

  • 1. Activin receptor-like kinase (ALK)1 is an antagonistic mediator of lateral TGFbeta/ALK5 signaling.
    Goumans MJ; Valdimarsdottir G; Itoh S; Lebrin F; Larsson J; Mummery C; Karlsson S; ten Dijke P
    Mol Cell; 2003 Oct; 12(4):817-28. PubMed ID: 14580334
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Balancing the activation state of the endothelium via two distinct TGF-beta type I receptors.
    Goumans MJ; Valdimarsdottir G; Itoh S; Rosendahl A; Sideras P; ten Dijke P
    EMBO J; 2002 Apr; 21(7):1743-53. PubMed ID: 11927558
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Activin receptor-like kinase 1 modulates transforming growth factor-beta 1 signaling in the regulation of angiogenesis.
    Oh SP; Seki T; Goss KA; Imamura T; Yi Y; Donahoe PK; Li L; Miyazono K; ten Dijke P; Kim S; Li E
    Proc Natl Acad Sci U S A; 2000 Mar; 97(6):2626-31. PubMed ID: 10716993
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Growth differentiation factor-9 signaling is mediated by the type I receptor, activin receptor-like kinase 5.
    Mazerbourg S; Klein C; Roh J; Kaivo-Oja N; Mottershead DG; Korchynskyi O; Ritvos O; Hsueh AJ
    Mol Endocrinol; 2004 Mar; 18(3):653-65. PubMed ID: 14684852
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Activin Receptor-Like Kinase Receptors ALK5 and ALK1 Are Both Required for TGFβ-Induced Chondrogenic Differentiation of Human Bone Marrow-Derived Mesenchymal Stem Cells.
    de Kroon LM; Narcisi R; Blaney Davidson EN; Cleary MA; van Beuningen HM; Koevoet WJ; van Osch GJ; van der Kraan PM
    PLoS One; 2015; 10(12):e0146124. PubMed ID: 26720610
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Poor vessel formation in embryos from knock-in mice expressing ALK5 with L45 loop mutation defective in Smad activation.
    Itoh F; Itoh S; Carvalho RL; Adachi T; Ema M; Goumans MJ; Larsson J; Karlsson S; Takahashi S; Mummery CL; Dijke PT; Kato M
    Lab Invest; 2009 Jul; 89(7):800-10. PubMed ID: 19398960
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Transforming growth factor-β stimulates Smad1/5 signaling in pulmonary artery smooth muscle cells and fibroblasts of the newborn mouse through ALK1.
    Zhang H; Du L; Zhong Y; Flanders KC; Roberts JD
    Am J Physiol Lung Cell Mol Physiol; 2017 Sep; 313(3):L615-L627. PubMed ID: 28642261
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Compensatory signalling induced in the yolk sac vasculature by deletion of TGFbeta receptors in mice.
    Carvalho RL; Itoh F; Goumans MJ; Lebrin F; Kato M; Takahashi S; Ema M; Itoh S; van Rooijen M; Bertolino P; Ten Dijke P; Mummery CL
    J Cell Sci; 2007 Dec; 120(Pt 24):4269-77. PubMed ID: 18029401
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Transforming growth factor-beta- and Activin-Smad signaling pathways are activated at distinct maturation stages of the thymopoeisis.
    Rosendahl A; Speletas M; Leandersson K; Ivars F; Sideras P
    Int Immunol; 2003 Dec; 15(12):1401-14. PubMed ID: 14645149
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Transforming growth factor-beta receptor type I-dependent fibrogenic gene program is mediated via activation of Smad1 and ERK1/2 pathways.
    Pannu J; Nakerakanti S; Smith E; ten Dijke P; Trojanowska M
    J Biol Chem; 2007 Apr; 282(14):10405-13. PubMed ID: 17317656
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Increase in ALK1/ALK5 ratio as a cause for elevated MMP-13 expression in osteoarthritis in humans and mice.
    Blaney Davidson EN; Remst DF; Vitters EL; van Beuningen HM; Blom AB; Goumans MJ; van den Berg WB; van der Kraan PM
    J Immunol; 2009 Jun; 182(12):7937-45. PubMed ID: 19494318
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Endoglin promotes endothelial cell proliferation and TGF-beta/ALK1 signal transduction.
    Lebrin F; Goumans MJ; Jonker L; Carvalho RL; Valdimarsdottir G; Thorikay M; Mummery C; Arthur HM; ten Dijke P
    EMBO J; 2004 Oct; 23(20):4018-28. PubMed ID: 15385967
    [TBL] [Abstract][Full Text] [Related]  

  • 13. SB-431542 is a potent and specific inhibitor of transforming growth factor-beta superfamily type I activin receptor-like kinase (ALK) receptors ALK4, ALK5, and ALK7.
    Inman GJ; Nicolás FJ; Callahan JF; Harling JD; Gaster LM; Reith AD; Laping NJ; Hill CS
    Mol Pharmacol; 2002 Jul; 62(1):65-74. PubMed ID: 12065756
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Endoglin null endothelial cells proliferate faster and are more responsive to transforming growth factor beta1 with higher affinity receptors and an activated Alk1 pathway.
    Pece-Barbara N; Vera S; Kathirkamathamby K; Liebner S; Di Guglielmo GM; Dejana E; Wrana JL; Letarte M
    J Biol Chem; 2005 Jul; 280(30):27800-8. PubMed ID: 15923183
    [TBL] [Abstract][Full Text] [Related]  

  • 15. ALK1 opposes ALK5/Smad3 signaling and expression of extracellular matrix components in human chondrocytes.
    Finnson KW; Parker WL; ten Dijke P; Thorikay M; Philip A
    J Bone Miner Res; 2008 Jun; 23(6):896-906. PubMed ID: 18333754
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Diabetes-relevant regulation of cultured blood outgrowth endothelial cells.
    Wang S; Hirschberg R
    Microvasc Res; 2009 Sep; 78(2):174-9. PubMed ID: 19539633
    [TBL] [Abstract][Full Text] [Related]  

  • 17. ALK5 and ALK1 play antagonistic roles in transforming growth factor β-induced podosome formation in aortic endothelial cells.
    Curado F; Spuul P; Egaña I; Rottiers P; Daubon T; Veillat V; Duhamel P; Leclercq A; Gontier E; Génot E
    Mol Cell Biol; 2014 Dec; 34(24):4389-403. PubMed ID: 25266657
    [TBL] [Abstract][Full Text] [Related]  

  • 18. ALK5- and TGFBR2-independent role of ALK1 in the pathogenesis of hereditary hemorrhagic telangiectasia type 2.
    Park SO; Lee YJ; Seki T; Hong KH; Fliess N; Jiang Z; Park A; Wu X; Kaartinen V; Roman BL; Oh SP
    Blood; 2008 Jan; 111(2):633-42. PubMed ID: 17911384
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Smad2/Smad3 in endothelium is indispensable for vascular stability via S1PR1 and N-cadherin expressions.
    Itoh F; Itoh S; Adachi T; Ichikawa K; Matsumura Y; Takagi T; Festing M; Watanabe T; Weinstein M; Karlsson S; Kato M
    Blood; 2012 May; 119(22):5320-8. PubMed ID: 22498737
    [TBL] [Abstract][Full Text] [Related]  

  • 20. TGF-{beta}1 activates two distinct type I receptors in neurons: implications for neuronal NF-{kappa}B signaling.
    König HG; Kögel D; Rami A; Prehn JH
    J Cell Biol; 2005 Mar; 168(7):1077-86. PubMed ID: 15781474
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 39.