137 related articles for article (PubMed ID: 14581930)
1. Assembly and activation of the gamma-secretase complex: roles of presenilin cofactors.
Iwatsubo T
Mol Psychiatry; 2004 Jan; 9(1):8-10. PubMed ID: 14581930
[No Abstract] [Full Text] [Related]
2. Alzheimer's disease. Closing in on gamma-secretase.
De Strooper B
Nature; 2000 Jun; 405(6787):627, 629. PubMed ID: 10864307
[No Abstract] [Full Text] [Related]
3. Total inactivation of gamma-secretase activity in presenilin-deficient embryonic stem cells.
Herreman A; Serneels L; Annaert W; Collen D; Schoonjans L; De Strooper B
Nat Cell Biol; 2000 Jul; 2(7):461-2. PubMed ID: 10878813
[No Abstract] [Full Text] [Related]
4. Presenilin function and gamma-secretase activity.
Brunkan AL; Goate AM
J Neurochem; 2005 May; 93(4):769-92. PubMed ID: 15857382
[TBL] [Abstract][Full Text] [Related]
5. Phosphorylation of amyloid precursor carboxy-terminal fragments enhances their processing by a gamma-secretase-dependent mechanism.
Vingtdeux V; Hamdane M; Gompel M; Bégard S; Drobecq H; Ghestem A; Grosjean ME; Kostanjevecki V; Grognet P; Vanmechelen E; Buée L; Delacourte A; Sergeant N
Neurobiol Dis; 2005 Nov; 20(2):625-37. PubMed ID: 15936948
[TBL] [Abstract][Full Text] [Related]
6. Proteolytic processing of the Alzheimer's disease amyloid precursor protein in brain and platelets.
Evin G; Zhu A; Holsinger RM; Masters CL; Li QX
J Neurosci Res; 2003 Nov; 74(3):386-92. PubMed ID: 14598315
[TBL] [Abstract][Full Text] [Related]
7. Presenilin modulates Pen-2 levels posttranslationally by protecting it from proteasomal degradation.
Crystal AS; Morais VA; Fortna RR; Carlin D; Pierson TC; Wilson CA; Lee VM; Doms RW
Biochemistry; 2004 Mar; 43(12):3555-63. PubMed ID: 15035625
[TBL] [Abstract][Full Text] [Related]
8. Distinct presenilin-dependent and presenilin-independent gamma-secretases are responsible for total cellular Abeta production.
Wilson CA; Doms RW; Lee VM
J Neurosci Res; 2003 Nov; 74(3):361-9. PubMed ID: 14598312
[TBL] [Abstract][Full Text] [Related]
9. [Presenilins in the genesis of Alzheimer s disease].
Pérez-Tur J
Rev Neurol; 2001 Nov 16-30; 33(10):967-72. PubMed ID: 11785012
[TBL] [Abstract][Full Text] [Related]
10. Alzheimer's disease. A partner for presenilin.
Schenk D
Nature; 2000 Sep; 407(6800):34-5. PubMed ID: 10993060
[No Abstract] [Full Text] [Related]
11. In vitro characterization of the presenilin-dependent gamma-secretase complex using a novel affinity ligand.
Beher D; Fricker M; Nadin A; Clarke EE; Wrigley JD; Li YM; Culvenor JG; Masters CL; Harrison T; Shearman MS
Biochemistry; 2003 Jul; 42(27):8133-42. PubMed ID: 12846562
[TBL] [Abstract][Full Text] [Related]
12. PEN-2 enhances gamma-cleavage after presenilin heterodimer formation.
Shiraishi H; Sai X; Wang HQ; Maeda Y; Kurono Y; Nishimura M; Yanagisawa K; Komano H
J Neurochem; 2004 Sep; 90(6):1402-13. PubMed ID: 15341524
[TBL] [Abstract][Full Text] [Related]
13. Presenilin clinical mutations can affect gamma-secretase activity by different mechanisms.
Bentahir M; Nyabi O; Verhamme J; Tolia A; Horré K; Wiltfang J; Esselmann H; De Strooper B
J Neurochem; 2006 Feb; 96(3):732-42. PubMed ID: 16405513
[TBL] [Abstract][Full Text] [Related]
14. Presenilin-directed inhibitors of gamma-secretase trigger caspase 3 activation in presenilin-expressing and presenilin-deficient cells.
Alves da Costa C; Ayral E; Hernandez JF; St George-Hyslop P; Checler F
J Neurochem; 2004 Aug; 90(4):800-6. PubMed ID: 15287885
[TBL] [Abstract][Full Text] [Related]
15. Gamma-secretase subunit composition and distribution in the presenilin wild-type and mutant mouse brain.
Siman R; Salidas S
Neuroscience; 2004; 129(3):615-28. PubMed ID: 15541883
[TBL] [Abstract][Full Text] [Related]
16. Mechanism of gamma-secretase cleavage activation: is gamma-secretase regulated through autoinhibition involving the presenilin-1 exon 9 loop?
Knappenberger KS; Tian G; Ye X; Sobotka-Briner C; Ghanekar SV; Greenberg BD; Scott CW
Biochemistry; 2004 May; 43(20):6208-18. PubMed ID: 15147205
[TBL] [Abstract][Full Text] [Related]
17. gamma-Secretase complexes containing N- and C-terminal fragments of different presenilin origin retain normal gamma-secretase activity.
Strömberg K; Hansson EM; Laudon H; Bergstedt S; Näslund J; Lundkvist J; Lendahl U
J Neurochem; 2005 Nov; 95(3):880-90. PubMed ID: 16135086
[TBL] [Abstract][Full Text] [Related]
18. [Pathogenesis of Alzheimer's disease: implications from amyloid research front].
Iwatsubo T
Rinsho Shinkeigaku; 2004 Nov; 44(11):768-70. PubMed ID: 15651286
[TBL] [Abstract][Full Text] [Related]
19. Familial Alzheimer's disease mutations inhibit gamma-secretase-mediated liberation of beta-amyloid precursor protein carboxy-terminal fragment.
Wiley JC; Hudson M; Kanning KC; Schecterson LC; Bothwell M
J Neurochem; 2005 Sep; 94(5):1189-201. PubMed ID: 15992373
[TBL] [Abstract][Full Text] [Related]
20. Intramembrane proteolysis by presenilins.
Steiner H; Haass C
Nat Rev Mol Cell Biol; 2000 Dec; 1(3):217-24. PubMed ID: 11252897
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]