BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

139 related articles for article (PubMed ID: 14582122)

  • 1. Invesgations [correction investigations] on the influence of halide substituents on the estrogen receptor interaction of 2, 4, 5-tris(4-hydroxyphenyl)imidazoles.
    Gust R; Busch S; Keilitz R; Schmidt K; Von Rauch M
    Arch Pharm (Weinheim); 2003 Oct; 336(10):456-65. PubMed ID: 14582122
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Antiestrogenically active 1,1,2-tris(4-hydroxyphenyl)alkenes without basic side chain: synthesis and biological activity.
    Lubczyk V; Bachmann H; Gust R
    J Med Chem; 2003 Apr; 46(8):1484-91. PubMed ID: 12672249
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Synthesis, structural evaluation, and estrogen receptor interaction of 4,5-bis(4-hydroxyphenyl)imidazoles.
    Gust R; Keilitz R; Schmidt K; von Rauch M
    Arch Pharm (Weinheim); 2002 Dec; 335(10):463-71. PubMed ID: 12506394
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Effects of C2-alkylation, N-alkylation, and N,N'-dialkylation on the stability and estrogen receptor interaction of (4R,5S)/(4S,5R)-4,5-bis(4-hydroxyphenyl)-2-imidazolines.
    von Rauch M; Schlenk M; Gust R
    J Med Chem; 2004 Feb; 47(4):915-27. PubMed ID: 14761193
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Investigations on the influence of terminal groups at the C2-propyl side chain of 1,1-bis(4-hydroxyphenyl)-2-phenylpent-1-ene and 1,1,2-tris(4-hydroxyphenyl)pent-1-ene on the estrogen receptor binding and the estrogenic/anti-estrogenic properties.
    Gust R; Lubczyk V
    J Steroid Biochem Mol Biol; 2003 Jul; 86(1):57-70. PubMed ID: 12943745
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Investigations on the effects of basic side chains on the hormonal profile of (4R,5S)/(4S,5R)-4,5-bis(4-hydroxyphenyl)-2-imidazolines.
    von Rauch M; Busch S; Gust R
    J Med Chem; 2005 Jan; 48(2):466-74. PubMed ID: 15658860
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Investigations on estrogen receptor binding. The estrogenic, antiestrogenic, and cytotoxic properties of C2-alkyl-substituted 1,1-bis(4-hydroxyphenyl)-2-phenylethenes.
    Lubczyk V; Bachmann H; Gust R
    J Med Chem; 2002 Nov; 45(24):5358-64. PubMed ID: 12431063
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Structure-activity relationship study to understand the estrogen receptor-dependent gene activation of aryl- and alkyl-substituted 1H-imidazoles.
    Wiglenda T; Gust R
    J Med Chem; 2007 Apr; 50(7):1475-84. PubMed ID: 17352461
    [TBL] [Abstract][Full Text] [Related]  

  • 9. (4R,5S)/(4S,5R)-4,5-Bis(4-hydroxyphenyl)-2-imidazolines: ligands for the estrogen receptor with a novel binding mode.
    Gust R; Keilitz R; Schmidt K; von Rauch M
    J Med Chem; 2002 Aug; 45(16):3356-65. PubMed ID: 12139447
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Investigations of new lead structures for the design of selective estrogen receptor modulators.
    Gust R; Keilitz R; Schmidt K
    J Med Chem; 2001 Jun; 44(12):1963-70. PubMed ID: 11384241
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Synthesis and pharmacological evaluation of 1H-imidazoles as ligands for the estrogen receptor and cytotoxic inhibitors of the cyclooxygenase.
    Wiglenda T; Ott I; Kircher B; Schumacher P; Schuster D; Langer T; Gust R
    J Med Chem; 2005 Oct; 48(20):6516-21. PubMed ID: 16190777
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Synthesis, structural evaluation, and estrogen receptor interaction of 2,3-diarylpiperazines.
    Gust R; Keilitz R; Schmidt K
    J Med Chem; 2002 May; 45(11):2325-37. PubMed ID: 12014971
    [TBL] [Abstract][Full Text] [Related]  

  • 13. [N-ethyl- and [N,N'-diethyl-1,2-bis(2,6-difluoro-3-hydroxyphenyl)-ethylenediamine]dichloroplatinum(II): structure and cytotoxic/estrogenic activity in breast cancer cells.
    Gust R; Niebler K; Schönenberger H
    J Med Chem; 2005 Nov; 48(23):7132-44. PubMed ID: 16279771
    [TBL] [Abstract][Full Text] [Related]  

  • 14. 1-(2,6-dichloro-4-hydroxyphenyl)-2-phenylethanes--new biological response modifiers for the therapy of breast cancer. Synthesis and evaluation of estrogenic/antiestrogenic properties.
    Schertl S; Hartmann RW; Batzl-Hartmann C; Schlemmer R; Spruss T; Bernhardt G; Gust R; Schönenberger H
    Arch Pharm (Weinheim); 2001 Apr; 334(4):125-37. PubMed ID: 11382148
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Synthesis, structure, and estrogenic activity of 4-amino-3-(2-methylbenzyl)coumarins on human breast carcinoma cells.
    Jacquot Y; Laïos I; Cleeren A; Nonclercq D; Bermont L; Refouvelet B; Boubekeur K; Xicluna A; Leclercq G; Laurent G
    Bioorg Med Chem; 2007 Mar; 15(6):2269-82. PubMed ID: 17275315
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Estrogen receptor modulators: identification and structure-activity relationships of potent ERalpha-selective tetrahydroisoquinoline ligands.
    Renaud J; Bischoff SF; Buhl T; Floersheim P; Fournier B; Halleux C; Kallen J; Keller H; Schlaeppi JM; Stark W
    J Med Chem; 2003 Jul; 46(14):2945-57. PubMed ID: 12825935
    [TBL] [Abstract][Full Text] [Related]  

  • 17. NHC gold halide complexes derived from 4,5-diarylimidazoles: synthesis, structural analysis, and pharmacological investigations as potential antitumor agents.
    Liu W; Bensdorf K; Proetto M; Abram U; Hagenbach A; Gust R
    J Med Chem; 2011 Dec; 54(24):8605-15. PubMed ID: 22091836
    [TBL] [Abstract][Full Text] [Related]  

  • 18. 2,5-Diphenylfuran-based pure antiestrogens with selectivity for the estrogen receptor alpha.
    Zimmermann J; Liebl R; von Angerer E
    J Steroid Biochem Mol Biol; 2005 Feb; 94(1-3):57-66. PubMed ID: 15862950
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Synthesis and evaluation of 17alpha-20E-21-(4-substituted phenyl)-19-norpregna-1,3,5(10),20-tetraene-3,17beta-diols as probes for the estrogen receptor alpha hormone binding domain.
    Hanson RN; Lee CY; Friel CJ; Dilis R; Hughes A; DeSombre ER
    J Med Chem; 2003 Jul; 46(14):2865-76. PubMed ID: 12825929
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Synthesis, biochemical properties and molecular modelling studies of organometallic specific estrogen receptor modulators (SERMs), the ferrocifens and hydroxyferrocifens: evidence for an antiproliferative effect of hydroxyferrocifens on both hormone-dependent and hormone-independent breast cancer cell lines.
    Top S; Vessières A; Leclercq G; Quivy J; Tang J; Vaissermann J; Huché M; Jaouen G
    Chemistry; 2003 Nov; 9(21):5223-36. PubMed ID: 14613131
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.