These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

819 related articles for article (PubMed ID: 14585926)

  • 21. 3C-like proteinase from SARS coronavirus catalyzes substrate hydrolysis by a general base mechanism.
    Huang C; Wei P; Fan K; Liu Y; Lai L
    Biochemistry; 2004 Apr; 43(15):4568-74. PubMed ID: 15078103
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Autoprocessing mechanism of severe acute respiratory syndrome coronavirus 3C-like protease (SARS-CoV 3CLpro) from its polyproteins.
    Muramatsu T; Kim YT; Nishii W; Terada T; Shirouzu M; Yokoyama S
    FEBS J; 2013 May; 280(9):2002-13. PubMed ID: 23452147
    [TBL] [Abstract][Full Text] [Related]  

  • 23. A mechanistic view of enzyme inhibition and peptide hydrolysis in the active site of the SARS-CoV 3C-like peptidase.
    Yin J; Niu C; Cherney MM; Zhang J; Huitema C; Eltis LD; Vederas JC; James MN
    J Mol Biol; 2007 Aug; 371(4):1060-74. PubMed ID: 17599357
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Cinanserin is an inhibitor of the 3C-like proteinase of severe acute respiratory syndrome coronavirus and strongly reduces virus replication in vitro.
    Chen L; Gui C; Luo X; Yang Q; Günther S; Scandella E; Drosten C; Bai D; He X; Ludewig B; Chen J; Luo H; Yang Y; Yang Y; Zou J; Thiel V; Chen K; Shen J; Shen X; Jiang H
    J Virol; 2005 Jun; 79(11):7095-103. PubMed ID: 15890949
    [TBL] [Abstract][Full Text] [Related]  

  • 25. A noncovalent class of papain-like protease/deubiquitinase inhibitors blocks SARS virus replication.
    Ratia K; Pegan S; Takayama J; Sleeman K; Coughlin M; Baliji S; Chaudhuri R; Fu W; Prabhakar BS; Johnson ME; Baker SC; Ghosh AK; Mesecar AD
    Proc Natl Acad Sci U S A; 2008 Oct; 105(42):16119-24. PubMed ID: 18852458
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Structure-based design and synthesis of highly potent SARS-CoV 3CL protease inhibitors.
    Shao YM; Yang WB; Peng HP; Hsu MF; Tsai KC; Kuo TH; Wang AH; Liang PH; Lin CH; Yang AS; Wong CH
    Chembiochem; 2007 Sep; 8(14):1654-7. PubMed ID: 17722121
    [No Abstract]   [Full Text] [Related]  

  • 27. Isatin compounds as noncovalent SARS coronavirus 3C-like protease inhibitors.
    Zhou L; Liu Y; Zhang W; Wei P; Huang C; Pei J; Yuan Y; Lai L
    J Med Chem; 2006 Jun; 49(12):3440-3. PubMed ID: 16759084
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Structural basis of mercury- and zinc-conjugated complexes as SARS-CoV 3C-like protease inhibitors.
    Lee CC; Kuo CJ; Hsu MF; Liang PH; Fang JM; Shie JJ; Wang AH
    FEBS Lett; 2007 Nov; 581(28):5454-8. PubMed ID: 17981158
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Inhibitor recognition specificity of MERS-CoV papain-like protease may differ from that of SARS-CoV.
    Lee H; Lei H; Santarsiero BD; Gatuz JL; Cao S; Rice AJ; Patel K; Szypulinski MZ; Ojeda I; Ghosh AK; Johnson ME
    ACS Chem Biol; 2015 Jun; 10(6):1456-65. PubMed ID: 25746232
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Two adjacent mutations on the dimer interface of SARS coronavirus 3C-like protease cause different conformational changes in crystal structure.
    Hu T; Zhang Y; Li L; Wang K; Chen S; Chen J; Ding J; Jiang H; Shen X
    Virology; 2009 Jun; 388(2):324-34. PubMed ID: 19409595
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Only one protomer is active in the dimer of SARS 3C-like proteinase.
    Chen H; Wei P; Huang C; Tan L; Liu Y; Lai L
    J Biol Chem; 2006 May; 281(20):13894-8. PubMed ID: 16565086
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Structural basis for the development of SARS 3CL protease inhibitors from a peptide mimic to an aza-decaline scaffold.
    Teruya K; Hattori Y; Shimamoto Y; Kobayashi K; Sanjoh A; Nakagawa A; Yamashita E; Akaji K
    Biopolymers; 2016 Nov; 106(4):391-403. PubMed ID: 26572934
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Discovery of potent anilide inhibitors against the severe acute respiratory syndrome 3CL protease.
    Shie JJ; Fang JM; Kuo CJ; Kuo TH; Liang PH; Huang HJ; Yang WB; Lin CH; Chen JL; Wu YT; Wong CH
    J Med Chem; 2005 Jun; 48(13):4469-73. PubMed ID: 15974598
    [TBL] [Abstract][Full Text] [Related]  

  • 34. The SARS-coronavirus papain-like protease: structure, function and inhibition by designed antiviral compounds.
    Báez-Santos YM; St John SE; Mesecar AD
    Antiviral Res; 2015 Mar; 115():21-38. PubMed ID: 25554382
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Substrate specificity and rational design of peptidomimetic inhibitors for SARS coronavirus main protease.
    Wong KB; Wan DC; Chow HF
    Hong Kong Med J; 2014 Aug; 20 Suppl 4():18-21. PubMed ID: 25224113
    [No Abstract]   [Full Text] [Related]  

  • 36. Design and Evaluation of Anti-SARS-Coronavirus Agents Based on Molecular Interactions with the Viral Protease.
    Akaji K; Konno H
    Molecules; 2020 Aug; 25(17):. PubMed ID: 32867349
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Steady-state and pre-steady-state kinetic evaluation of severe acute respiratory syndrome coronavirus (SARS-CoV) 3CLpro cysteine protease: development of an ion-pair model for catalysis.
    Solowiej J; Thomson JA; Ryan K; Luo C; He M; Lou J; Murray BW
    Biochemistry; 2008 Feb; 47(8):2617-30. PubMed ID: 18237196
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Severe acute respiratory syndrome coronavirus 3C-like proteinase N terminus is indispensable for proteolytic activity but not for enzyme dimerization. Biochemical and thermodynamic investigation in conjunction with molecular dynamics simulations.
    Chen S; Chen L; Tan J; Chen J; Du L; Sun T; Shen J; Chen K; Jiang H; Shen X
    J Biol Chem; 2005 Jan; 280(1):164-73. PubMed ID: 15507456
    [TBL] [Abstract][Full Text] [Related]  

  • 39. SARS-CoV and SARS-CoV-2 main protease residue interaction networks change when bound to inhibitor N3.
    Griffin JWD
    J Struct Biol; 2020 Sep; 211(3):107575. PubMed ID: 32653646
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Mechanism for controlling the dimer-monomer switch and coupling dimerization to catalysis of the severe acute respiratory syndrome coronavirus 3C-like protease.
    Shi J; Sivaraman J; Song J
    J Virol; 2008 May; 82(9):4620-9. PubMed ID: 18305031
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 41.