485 related articles for article (PubMed ID: 14592453)
1. Characterizing the effects of saturated fatty acids on insulin signaling and ceramide and diacylglycerol accumulation in 3T3-L1 adipocytes and C2C12 myotubes.
Chavez JA; Summers SA
Arch Biochem Biophys; 2003 Nov; 419(2):101-9. PubMed ID: 14592453
[TBL] [Abstract][Full Text] [Related]
2. Ceramide generation is sufficient to account for the inhibition of the insulin-stimulated PKB pathway in C2C12 skeletal muscle cells pretreated with palmitate.
Schmitz-Peiffer C; Craig DL; Biden TJ
J Biol Chem; 1999 Aug; 274(34):24202-10. PubMed ID: 10446195
[TBL] [Abstract][Full Text] [Related]
3. A role for ceramide, but not diacylglycerol, in the antagonism of insulin signal transduction by saturated fatty acids.
Chavez JA; Knotts TA; Wang LP; Li G; Dobrowsky RT; Florant GL; Summers SA
J Biol Chem; 2003 Mar; 278(12):10297-303. PubMed ID: 12525490
[TBL] [Abstract][Full Text] [Related]
4. Modulation of cellular insulin signaling and PTP1B effects by lipid metabolites in skeletal muscle cells.
Obanda DN; Cefalu WT
J Nutr Biochem; 2013 Aug; 24(8):1529-37. PubMed ID: 23481236
[TBL] [Abstract][Full Text] [Related]
5. Oleate dose-dependently regulates palmitate metabolism and insulin signaling in C2C12 myotubes.
Capel F; Cheraiti N; Acquaviva C; Hénique C; Bertrand-Michel J; Vianey-Saban C; Prip-Buus C; Morio B
Biochim Biophys Acta; 2016 Dec; 1861(12 Pt A):2000-2010. PubMed ID: 27725263
[TBL] [Abstract][Full Text] [Related]
6. Saturated, but not n-6 polyunsaturated, fatty acids induce insulin resistance: role of intramuscular accumulation of lipid metabolites.
Lee JS; Pinnamaneni SK; Eo SJ; Cho IH; Pyo JH; Kim CK; Sinclair AJ; Febbraio MA; Watt MJ
J Appl Physiol (1985); 2006 May; 100(5):1467-74. PubMed ID: 16357064
[TBL] [Abstract][Full Text] [Related]
7. Fatty acid-induced defects in insulin signalling, in myotubes derived from children, are related to ceramide production from palmitate rather than the accumulation of intramyocellular lipid.
Sabin MA; Stewart CE; Crowne EC; Turner SJ; Hunt LP; Welsh GI; Grohmann MJ; Holly JM; Shield JP
J Cell Physiol; 2007 Apr; 211(1):244-52. PubMed ID: 17219404
[TBL] [Abstract][Full Text] [Related]
8. Downregulation of lipin-1 induces insulin resistance by increasing intracellular ceramide accumulation in C2C12 myotubes.
Huang S; Huang S; Wang X; Zhang Q; Liu J; Leng Y
Int J Biol Sci; 2017; 13(1):1-12. PubMed ID: 28123341
[TBL] [Abstract][Full Text] [Related]
9. Intracellular ceramide synthesis and protein kinase Czeta activation play an essential role in palmitate-induced insulin resistance in rat L6 skeletal muscle cells.
Powell DJ; Turban S; Gray A; Hajduch E; Hundal HS
Biochem J; 2004 Sep; 382(Pt 2):619-29. PubMed ID: 15193147
[TBL] [Abstract][Full Text] [Related]
10. Acid ceramidase overexpression prevents the inhibitory effects of saturated fatty acids on insulin signaling.
Chavez JA; Holland WL; Bär J; Sandhoff K; Summers SA
J Biol Chem; 2005 May; 280(20):20148-53. PubMed ID: 15774472
[TBL] [Abstract][Full Text] [Related]
11. Sustained Action of Ceramide on the Insulin Signaling Pathway in Muscle Cells: IMPLICATION OF THE DOUBLE-STRANDED RNA-ACTIVATED PROTEIN KINASE.
Hage Hassan R; Pacheco de Sousa AC; Mahfouz R; Hainault I; Blachnio-Zabielska A; Bourron O; Koskas F; Górski J; Ferré P; Foufelle F; Hajduch E
J Biol Chem; 2016 Feb; 291(6):3019-29. PubMed ID: 26698173
[TBL] [Abstract][Full Text] [Related]
12. Modulating serine palmitoyl transferase (SPT) expression and activity unveils a crucial role in lipid-induced insulin resistance in rat skeletal muscle cells.
Watson ML; Coghlan M; Hundal HS
Biochem J; 2009 Feb; 417(3):791-801. PubMed ID: 18922131
[TBL] [Abstract][Full Text] [Related]
13. A role for protein phosphatase 2A-like activity, but not atypical protein kinase Czeta, in the inhibition of protein kinase B/Akt and glycogen synthesis by palmitate.
Cazzolli R; Carpenter L; Biden TJ; Schmitz-Peiffer C
Diabetes; 2001 Oct; 50(10):2210-8. PubMed ID: 11574400
[TBL] [Abstract][Full Text] [Related]
14. A Role for Ceramides, but Not Sphingomyelins, as Antagonists of Insulin Signaling and Mitochondrial Metabolism in C2C12 Myotubes.
Park M; Kaddai V; Ching J; Fridianto KT; Sieli RJ; Sugii S; Summers SA
J Biol Chem; 2016 Nov; 291(46):23978-23988. PubMed ID: 27703011
[TBL] [Abstract][Full Text] [Related]
15. Different impacts of saturated and unsaturated free fatty acids on COX-2 expression in C(2)C(12) myotubes.
Kadotani A; Tsuchiya Y; Hatakeyama H; Katagiri H; Kanzaki M
Am J Physiol Endocrinol Metab; 2009 Dec; 297(6):E1291-303. PubMed ID: 19755671
[TBL] [Abstract][Full Text] [Related]
16. Characterising the inhibitory actions of ceramide upon insulin signaling in different skeletal muscle cell models: a mechanistic insight.
Mahfouz R; Khoury R; Blachnio-Zabielska A; Turban S; Loiseau N; Lipina C; Stretton C; Bourron O; Ferré P; Foufelle F; Hundal HS; Hajduch E
PLoS One; 2014; 9(7):e101865. PubMed ID: 25058613
[TBL] [Abstract][Full Text] [Related]
17. Ceramide mediates inhibition of the AKT/eNOS signaling pathway by palmitate in human vascular endothelial cells.
Xiao-Yun X; Zhuo-Xiong C; Min-Xiang L; Xingxuan H; Schuchman EH; Feng L; Han-Song X; An-Hua L
Med Sci Monit; 2009 Sep; 15(9):BR254-61. PubMed ID: 19721393
[TBL] [Abstract][Full Text] [Related]
18. Increased beta-oxidation in muscle cells enhances insulin-stimulated glucose metabolism and protects against fatty acid-induced insulin resistance despite intramyocellular lipid accumulation.
Perdomo G; Commerford SR; Richard AM; Adams SH; Corkey BE; O'Doherty RM; Brown NF
J Biol Chem; 2004 Jun; 279(26):27177-86. PubMed ID: 15105415
[TBL] [Abstract][Full Text] [Related]
19. Key role for ceramides in mediating insulin resistance in human muscle cells.
Pickersgill L; Litherland GJ; Greenberg AS; Walker M; Yeaman SJ
J Biol Chem; 2007 Apr; 282(17):12583-9. PubMed ID: 17337731
[TBL] [Abstract][Full Text] [Related]
20. Leptin, skeletal muscle lipids, and lipid-induced insulin resistance.
Dube JJ; Bhatt BA; Dedousis N; Bonen A; O'Doherty RM
Am J Physiol Regul Integr Comp Physiol; 2007 Aug; 293(2):R642-50. PubMed ID: 17491114
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
