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9. Aryl tetrahydropyridine inhibitors of farnesyltransferase: glycine, phenylalanine and histidine derivatives. Gwaltney SL; O'Connor SJ; Nelson LT; Sullivan GM; Imade H; Wang W; Hasvold L; Li Q; Cohen J; Gu WZ; Tahir SK; Bauch J; Marsh K; Ng SC; Frost DJ; Zhang H; Muchmore S; Jakob CG; Stoll V; Hutchins C; Rosenberg SH; Sham HL Bioorg Med Chem Lett; 2003 Apr; 13(7):1359-62. PubMed ID: 12657282 [TBL] [Abstract][Full Text] [Related]
10. 4-methyl-1,2,4-triazol-3-yl heterocycle as an alternative to the 1-methylimidazol-5-yl moiety in the farnesyltransferase inhibitor ZARNESTRA. Angibaud P; Saha AK; Bourdrez X; End DW; Freyne E; Lezouret P; Mannens G; Mevellec L; Meyer C; Pilatte I; Poncelet V; Roux B; Smets G; Van Dun J; Venet M; Wouters W Bioorg Med Chem Lett; 2003 Dec; 13(24):4361-4. PubMed ID: 14643326 [TBL] [Abstract][Full Text] [Related]
11. Synthesis and evaluation of homofarnesoyl-substituted CAAX-peptidomimetics as farnesyltransferase inhibitors and antiproliferative agents. Schlitzer M; Sattler I; Dahse HM Bioorg Med Chem; 1999 Sep; 7(9):2037-45. PubMed ID: 10530953 [TBL] [Abstract][Full Text] [Related]
12. Novel conformationally extended naphthalene-based inhibitors of farnesyltransferase. Burns CJ; Guitton JD; Baudoin B; Lelièvre Y; Duchesne M; Parker F; Fromage N; Commerçon A J Med Chem; 1997 Jun; 40(12):1763-7. PubMed ID: 9191950 [No Abstract] [Full Text] [Related]
13. Synthesis and activity of 1-aryl-1'-imidazolyl methyl ethers as non-thiol farnesyltransferase inhibitors. Li Q; Wang GT; Li T; Gwaltney SL; Woods KW; Claiborne A; Wang X; Gu W; Cohen J; Stoll VS; Hutchins C; Frost D; Rosenberg SH; Sham HL Bioorg Med Chem Lett; 2004 Nov; 14(21):5371-6. PubMed ID: 15454229 [TBL] [Abstract][Full Text] [Related]
14. Non-thiol farnesyltransferase inhibitors: structure-activity relationships of benzophenone-based bisubstrate analogue farnesyltransferase inhibitors. Schlitzer M; Böhm M; Sattler I Bioorg Med Chem; 2002 Mar; 10(3):615-20. PubMed ID: 11814849 [TBL] [Abstract][Full Text] [Related]
16. 2-substituted piperazines as constrained amino acids. Application to the synthesis of potent, non carboxylic acid inhibitors of farnesyltransferase. Williams TM; Ciccarone TM; MacTough SC; Bock RL; Conner MW; Davide JP; Hamilton K; Koblan KS; Kohl NE; Kral AM; Mosser SD; Omer CA; Pompliano DL; Rands E; Schaber MD; Shah D; Wilson FR; Gibbs JB; Graham SL; Hartman GD; Oliff AI; Smith RL J Med Chem; 1996 Mar; 39(7):1345-8. PubMed ID: 8691462 [No Abstract] [Full Text] [Related]
17. [Inhibitors of farnesyltransferase: a new approach for development of potential cancer drugs]. Schlitzer M Pharm Unserer Zeit; 1998 Nov; 27(6):278-88. PubMed ID: 9894422 [No Abstract] [Full Text] [Related]
18. Farnesyltransferase inhibitors. Adjei AA Cancer Chemother Biol Response Modif; 2003; 21():127-44. PubMed ID: 15338743 [No Abstract] [Full Text] [Related]
19. Design and biological activity of (S)-4-(5-([1-(3-chlorobenzyl)-2-oxopyrrolidin-3-ylamino]methyl)imidazol-1-ylmethyl)benzonitrile, a 3-aminopyrrolidinone farnesyltransferase inhibitor with excellent cell potency. Bell IM; Gallicchio SN; Abrams M; Beshore DC; Buser CA; Culberson JC; Davide J; Ellis-Hutchings M; Fernandes C; Gibbs JB; Graham SL; Hartman GD; Heimbrook DC; Homnick CF; Huff JR; Kassahun K; Koblan KS; Kohl NE; Lobell RB; Lynch JJ; Miller PA; Omer CA; Rodrigues AD; Walsh ES; Williams TM J Med Chem; 2001 Aug; 44(18):2933-49. PubMed ID: 11520202 [TBL] [Abstract][Full Text] [Related]
20. Farnesyltransferase and geranylgeranyltransferase I inhibitors and cancer therapy: lessons from mechanism and bench-to-bedside translational studies. Sebti SM; Hamilton AD Oncogene; 2000 Dec; 19(56):6584-93. PubMed ID: 11426643 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]