BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

402 related articles for article (PubMed ID: 14596593)

  • 1. Cellular effects of small molecule PTP1B inhibitors on insulin signaling.
    Xie L; Lee SY; Andersen JN; Waters S; Shen K; Guo XL; Moller NP; Olefsky JM; Lawrence DS; Zhang ZY
    Biochemistry; 2003 Nov; 42(44):12792-804. PubMed ID: 14596593
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Reduction of protein tyrosine phosphatase 1B increases insulin-dependent signaling in ob/ob mice.
    Gum RJ; Gaede LL; Koterski SL; Heindel M; Clampit JE; Zinker BA; Trevillyan JM; Ulrich RG; Jirousek MR; Rondinone CM
    Diabetes; 2003 Jan; 52(1):21-8. PubMed ID: 12502489
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Mechanism for differential effect of protein-tyrosine phosphatase 1B on Akt versus mitogen-activated protein kinase in 3T3-L1 adipocytes.
    Shimizu S; Maegawa H; Egawa K; Shi K; Bryer-Ash M; Kashiwagi A
    Endocrinology; 2002 Dec; 143(12):4563-9. PubMed ID: 12446583
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Coordinated regulation of insulin signaling by the protein tyrosine phosphatases PTP1B and TCPTP.
    Galic S; Hauser C; Kahn BB; Haj FG; Neel BG; Tonks NK; Tiganis T
    Mol Cell Biol; 2005 Jan; 25(2):819-29. PubMed ID: 15632081
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Hyrtiosal, a PTP1B inhibitor from the marine sponge Hyrtios erectus, shows extensive cellular effects on PI3K/AKT activation, glucose transport, and TGFbeta/Smad2 signaling.
    Sun T; Wang Q; Yu Z; Zhang Y; Guo Y; Chen K; Shen X; Jiang H
    Chembiochem; 2007 Jan; 8(2):187-93. PubMed ID: 17183521
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Overexpression of protein-tyrosine phosphatase-1B in adipocytes inhibits insulin-stimulated phosphoinositide 3-kinase activity without altering glucose transport or Akt/Protein kinase B activation.
    Venable CL; Frevert EU; Kim YB; Fischer BM; Kamatkar S; Neel BG; Kahn BB
    J Biol Chem; 2000 Jun; 275(24):18318-26. PubMed ID: 10751417
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Angiotensin II impairs the insulin signaling pathway promoting production of nitric oxide by inducing phosphorylation of insulin receptor substrate-1 on Ser312 and Ser616 in human umbilical vein endothelial cells.
    Andreozzi F; Laratta E; Sciacqua A; Perticone F; Sesti G
    Circ Res; 2004 May; 94(9):1211-8. PubMed ID: 15044323
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Phosphorylation of PTP1B at Ser(50) by Akt impairs its ability to dephosphorylate the insulin receptor.
    Ravichandran LV; Chen H; Li Y; Quon MJ
    Mol Endocrinol; 2001 Oct; 15(10):1768-80. PubMed ID: 11579209
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Developmental switch from prolonged insulin action to increased insulin sensitivity in protein tyrosine phosphatase 1B-deficient hepatocytes.
    Gonzalez-Rodriguez A; Clampit JE; Escribano O; Benito M; Rondinone CM; Valverde AM
    Endocrinology; 2007 Feb; 148(2):594-608. PubMed ID: 17068137
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Reduction of protein-tyrosine phosphatase-1B increases insulin signaling in FAO hepatoma cells.
    Clampit JE; Meuth JL; Smith HT; Reilly RM; Jirousek MR; Trevillyan JM; Rondinone CM
    Biochem Biophys Res Commun; 2003 Jan; 300(2):261-7. PubMed ID: 12504077
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Hyperglycemia potentiates H(2)O(2) production in adipocytes and enhances insulin signal transduction: potential role for oxidative inhibition of thiol-sensitive protein-tyrosine phosphatases.
    Wu X; Zhu L; Zilbering A; Mahadev K; Motoshima H; Yao J; Goldstein BJ
    Antioxid Redox Signal; 2005; 7(5-6):526-37. PubMed ID: 15889998
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Differential regulation of the phosphoinositide 3-kinase and MAP kinase pathways by hepatocyte growth factor vs. insulin-like growth factor-I in myogenic cells.
    Halevy O; Cantley LC
    Exp Cell Res; 2004 Jul; 297(1):224-34. PubMed ID: 15194438
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Protein-tyrosine phosphatase-1B negatively regulates insulin signaling in l6 myocytes and Fao hepatoma cells.
    Egawa K; Maegawa H; Shimizu S; Morino K; Nishio Y; Bryer-Ash M; Cheung AT; Kolls JK; Kikkawa R; Kashiwagi A
    J Biol Chem; 2001 Mar; 276(13):10207-11. PubMed ID: 11136729
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Insulin signaling leading to proliferation, survival, and membrane ruffling in C2C12 myoblasts.
    Conejo R; Lorenzo M
    J Cell Physiol; 2001 Apr; 187(1):96-108. PubMed ID: 11241354
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Small molecule peptidomimetics containing a novel phosphotyrosine bioisostere inhibit protein tyrosine phosphatase 1B and augment insulin action.
    Bleasdale JE; Ogg D; Palazuk BJ; Jacob CS; Swanson ML; Wang XY; Thompson DP; Conradi RA; Mathews WR; Laborde AL; Stuchly CW; Heijbel A; Bergdahl K; Bannow CA; Smith CW; Svensson C; Liljebris C; Schostarez HJ; May PD; Stevens FC; Larsen SD
    Biochemistry; 2001 May; 40(19):5642-54. PubMed ID: 11341829
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Fibroblast growth factor receptor signaling activates the human interstitial collagenase promoter via the bipartite Ets-AP1 element.
    Newberry EP; Willis D; Latifi T; Boudreaux JM; Towler DA
    Mol Endocrinol; 1997 Jul; 11(8):1129-44. PubMed ID: 9212060
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Early signaling events triggered by peroxovanadium [bpV(phen)] are insulin receptor kinase (IRK)-dependent: specificity of inhibition of IRK-associated protein tyrosine phosphatase(s) by bpV(phen).
    Band CJ; Posner BI; Dumas V; Contreres JO
    Mol Endocrinol; 1997 Dec; 11(13):1899-910. PubMed ID: 9415395
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The chimeric protein tyrosine kinase ETV6-NTRK3 requires both Ras-Erk1/2 and PI3-kinase-Akt signaling for fibroblast transformation.
    Tognon C; Garnett M; Kenward E; Kay R; Morrison K; Sorensen PH
    Cancer Res; 2001 Dec; 61(24):8909-16. PubMed ID: 11751416
    [TBL] [Abstract][Full Text] [Related]  

  • 19. NO attenuates insulin signaling and motility in aortic smooth muscle cells via protein tyrosine phosphatase 1B-mediated mechanism.
    Sreejayan N; Lin Y; Hassid A
    Arterioscler Thromb Vasc Biol; 2002 Jul; 22(7):1086-92. PubMed ID: 12117721
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Modulation of IR/PTP1B interaction and downstream signaling in insulin sensitive tissues of MSG-rats.
    Hirata AE; Alvarez-Rojas F; Carvalheira JB; Carvalho CR; Dolnikoff MS; Abdalla Saad MJ
    Life Sci; 2003 Aug; 73(11):1369-81. PubMed ID: 12850498
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 21.