BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

282 related articles for article (PubMed ID: 14597630)

  • 1. Prolonged kappa opioid receptor phosphorylation mediated by G-protein receptor kinase underlies sustained analgesic tolerance.
    McLaughlin JP; Myers LC; Zarek PE; Caron MG; Lefkowitz RJ; Czyzyk TA; Pintar JE; Chavkin C
    J Biol Chem; 2004 Jan; 279(3):1810-8. PubMed ID: 14597630
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Kappa opioid receptor activation of p38 MAPK is GRK3- and arrestin-dependent in neurons and astrocytes.
    Bruchas MR; Macey TA; Lowe JD; Chavkin C
    J Biol Chem; 2006 Jun; 281(26):18081-9. PubMed ID: 16648139
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Estrogen Regulation of GRK2 Inactivates Kappa Opioid Receptor Signaling Mediating Analgesia, But Not Aversion.
    Abraham AD; Schattauer SS; Reichard KL; Cohen JH; Fontaine HM; Song AJ; Johnson SD; Land BB; Chavkin C
    J Neurosci; 2018 Sep; 38(37):8031-8043. PubMed ID: 30076211
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Investigation of the role of βarrestin2 in kappa opioid receptor modulation in a mouse model of pruritus.
    Morgenweck J; Frankowski KJ; Prisinzano TE; Aubé J; Bohn LM
    Neuropharmacology; 2015 Dec; 99():600-9. PubMed ID: 26318102
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Molecular basis of differences in (-)(trans)-3,4-dichloro-N-methyl-N-[2-(1-pyrrolidiny)-cyclohexyl]benzeneacetamide-induced desensitization and phosphorylation between human and rat kappa-opioid receptors expressed in Chinese hamster ovary cells.
    Li J; Li JG; Chen C; Zhang F; Liu-Chen LY
    Mol Pharmacol; 2002 Jan; 61(1):73-84. PubMed ID: 11752208
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Neuropathic pain activates the endogenous kappa opioid system in mouse spinal cord and induces opioid receptor tolerance.
    Xu M; Petraschka M; McLaughlin JP; Westenbroek RE; Caron MG; Lefkowitz RJ; Czyzyk TA; Pintar JE; Terman GW; Chavkin C
    J Neurosci; 2004 May; 24(19):4576-84. PubMed ID: 15140929
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Sciatic nerve ligation-induced proliferation of spinal cord astrocytes is mediated by kappa opioid activation of p38 mitogen-activated protein kinase.
    Xu M; Bruchas MR; Ippolito DL; Gendron L; Chavkin C
    J Neurosci; 2007 Mar; 27(10):2570-81. PubMed ID: 17344394
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Agonist-promoted kappa opioid receptor (KOR) phosphorylation has behavioral endpoint-dependent and sex-specific effects.
    Huang P; Chen C; Cao D; Huang M; Liu-Chen LY
    Neuropharmacology; 2022 Jan; 202():108860. PubMed ID: 34736959
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Agonist-Dependent and -Independent κ Opioid Receptor Phosphorylation: Distinct Phosphorylation Patterns and Different Cellular Outcomes.
    Chiu YT; Chen C; Yu D; Schulz S; Liu-Chen LY
    Mol Pharmacol; 2017 Nov; 92(5):588-600. PubMed ID: 28893975
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Kappa Opioid Receptor-Induced Aversion Requires p38 MAPK Activation in VTA Dopamine Neurons.
    Ehrich JM; Messinger DI; Knakal CR; Kuhar JR; Schattauer SS; Bruchas MR; Zweifel LS; Kieffer BL; Phillips PE; Chavkin C
    J Neurosci; 2015 Sep; 35(37):12917-31. PubMed ID: 26377476
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Quantification of kappa opioid receptor ligand potency, efficacy and desensitization using a real-time membrane potential assay.
    Zhao Y; Joshi AA; Aldrich JV; Murray TF
    Biomed Pharmacother; 2021 Nov; 143():112173. PubMed ID: 34536757
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Phosphorylation of a carboxyl-terminal serine within the kappa-opioid receptor produces desensitization and internalization.
    McLaughlin JP; Xu M; Mackie K; Chavkin C
    J Biol Chem; 2003 Sep; 278(36):34631-40. PubMed ID: 12815037
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The dysphoric component of stress is encoded by activation of the dynorphin kappa-opioid system.
    Land BB; Bruchas MR; Lemos JC; Xu M; Melief EJ; Chavkin C
    J Neurosci; 2008 Jan; 28(2):407-14. PubMed ID: 18184783
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Involvement of kappa opioid receptors in formalin-induced inhibition of analgesic tolerance to morphine in mice.
    Tokuyama S; Nagae R; Mashida E; Hamabe W
    J Pharm Pharmacol; 2007 Aug; 59(8):1109-15. PubMed ID: 17725853
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Kappa-opioid receptors on lymphocytes of a human lymphocytic cell line: morphine-induced up-regulation as evidenced by competitive RT-PCR and indirect immunofluorescence.
    Suzuki S; Chuang LF; Doi RH; Bidlack JM; Chuang RY
    Int Immunopharmacol; 2001 Sep; 1(9-10):1733-42. PubMed ID: 11562065
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Involvement of kappa opioid receptors in the inhibition of receptor desensitization and PKC activation induced by repeated morphine treatment.
    Hamabe W; Yamane H; Harada S; Tokuyama S
    J Pharm Pharmacol; 2008 Sep; 60(9):1183-8. PubMed ID: 18718122
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Locus coeruleus kappa-opioid receptors modulate reinstatement of cocaine place preference through a noradrenergic mechanism.
    Al-Hasani R; McCall JG; Foshage AM; Bruchas MR
    Neuropsychopharmacology; 2013 Nov; 38(12):2484-97. PubMed ID: 23787819
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Phosphoproteomic approach for agonist-specific signaling in mouse brains: mTOR pathway is involved in κ opioid aversion.
    Liu JJ; Chiu YT; DiMattio KM; Chen C; Huang P; Gentile TA; Muschamp JW; Cowan A; Mann M; Liu-Chen LY
    Neuropsychopharmacology; 2019 Apr; 44(5):939-949. PubMed ID: 30082888
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Activation of the kappa opioid receptor in the dorsal raphe nucleus mediates the aversive effects of stress and reinstates drug seeking.
    Land BB; Bruchas MR; Schattauer S; Giardino WJ; Aita M; Messinger D; Hnasko TS; Palmiter RD; Chavkin C
    Proc Natl Acad Sci U S A; 2009 Nov; 106(45):19168-73. PubMed ID: 19864633
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Stress-induced p38 mitogen-activated protein kinase activation mediates kappa-opioid-dependent dysphoria.
    Bruchas MR; Land BB; Aita M; Xu M; Barot SK; Li S; Chavkin C
    J Neurosci; 2007 Oct; 27(43):11614-23. PubMed ID: 17959804
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 15.