166 related articles for article (PubMed ID: 14604280)
1. N-(4-Hydroxyphenyl)retinamide (4-HPR) induces leukemia cell death via generation of reactive oxygen species.
Goto H; Takahashi H; Fujii H; Ikuta K; Yokota S
Int J Hematol; 2003 Oct; 78(3):219-25. PubMed ID: 14604280
[TBL] [Abstract][Full Text] [Related]
2. Intracellular glutathione levels determine cell sensitivity to apoptosis induced by the antineoplasic agent N-(4-hydroxyphenyl) retinamide.
Morales MC; Pérez-Yarza G; Nieto-Rementeria N; Boyano MD; Jangi M; Atencia R; Asumendi A
Anticancer Res; 2005; 25(3B):1945-51. PubMed ID: 16158929
[TBL] [Abstract][Full Text] [Related]
3. Increase of ceramide and induction of mixed apoptosis/necrosis by N-(4-hydroxyphenyl)- retinamide in neuroblastoma cell lines.
Maurer BJ; Metelitsa LS; Seeger RC; Cabot MC; Reynolds CP
J Natl Cancer Inst; 1999 Jul; 91(13):1138-46. PubMed ID: 10393722
[TBL] [Abstract][Full Text] [Related]
4. Mechanism of synergy of N-(4-hydroxyphenyl)retinamide and ABT-737 in acute lymphoblastic leukemia cell lines: Mcl-1 inactivation.
Kang MH; Wan Z; Kang YH; Sposto R; Reynolds CP
J Natl Cancer Inst; 2008 Apr; 100(8):580-95. PubMed ID: 18398104
[TBL] [Abstract][Full Text] [Related]
5. Dynamics of ceramide generation and metabolism in response to fenretinide--Diversity within and among leukemia.
Morad SA; Davis TS; Kester M; Loughran TP; Cabot MC
Leuk Res; 2015 Oct; 39(10):1071-8. PubMed ID: 26220867
[TBL] [Abstract][Full Text] [Related]
6. Dihydroceramide accumulation and reactive oxygen species are distinct and nonessential events in 4-HPR-mediated leukemia cell death.
Apraiz A; Idkowiak-Baldys J; Nieto-Rementería N; Boyano MD; Hannun YA; Asumendi A
Biochem Cell Biol; 2012 Apr; 90(2):209-23. PubMed ID: 22428532
[TBL] [Abstract][Full Text] [Related]
7. Fenretinide cytotoxicity is independent of both constitutive and pharmacologically modulated glutathione levels in pediatric acute lymphoblastic leukemia cells cultured at hypoxia.
Cooper JP; Bang S; Singh H; Williams SC; Kang MH
Pediatr Blood Cancer; 2012 Jun; 58(6):994-7. PubMed ID: 22532987
[TBL] [Abstract][Full Text] [Related]
8. N-(4-hydroxyphenyl)retinamide increases ceramide and is cytotoxic to acute lymphoblastic leukemia cell lines, but not to non-malignant lymphocytes.
O'Donnell PH; Guo WX; Reynolds CP; Maurer BJ
Leukemia; 2002 May; 16(5):902-10. PubMed ID: 11986953
[TBL] [Abstract][Full Text] [Related]
9. ROS-driven Akt dephosphorylation at Ser-473 is involved in 4-HPR-mediated apoptosis in NB4 cells.
Cao J; Xu D; Wang D; Wu R; Zhang L; Zhu H; He Q; Yang B
Free Radic Biol Med; 2009 Sep; 47(5):536-47. PubMed ID: 19482076
[TBL] [Abstract][Full Text] [Related]
10. Fenretinide cytotoxicity for Ewing's sarcoma and primitive neuroectodermal tumor cell lines is decreased by hypoxia and synergistically enhanced by ceramide modulators.
Batra S; Reynolds CP; Maurer BJ
Cancer Res; 2004 Aug; 64(15):5415-24. PubMed ID: 15289350
[TBL] [Abstract][Full Text] [Related]
11. [Mechanisms of fenretinide-triggered apoptosis in leukemic cells].
Xiao DK; Du YZ; Fan HY; Chen YL; Chen Z; Zhang J; Wang KK
Zhongguo Shi Yan Xue Ye Xue Za Zhi; 2005 Dec; 13(6):975-8. PubMed ID: 16403262
[TBL] [Abstract][Full Text] [Related]
12. 4-oxo-N-(4-hydroxyphenyl)retinamide: two independent ways to kill cancer cells.
Tiberio P; Cavadini E; Abolafio G; Formelli F; Appierto V
PLoS One; 2010 Oct; 5(10):e13362. PubMed ID: 20976277
[TBL] [Abstract][Full Text] [Related]
13. Hypoxia-mediated fenretinide (4-HPR) resistance in childhood acute lymphoblastic leukemia cells.
Yang B; Fan L; Fang L; He Q
Cancer Chemother Pharmacol; 2006 Oct; 58(4):540-6. PubMed ID: 16520989
[TBL] [Abstract][Full Text] [Related]
14. N-(4-Hydroxylphenyl)retinamide (fenretinide, 4-HPR), a retinoid compound with antileukemic and proapoptotic activity in acute lymphoblastic leukemia (ALL).
Faderl S; Lotan R; Kantarjian HM; Harris D; Van Q; Estrov Z
Leuk Res; 2003 Mar; 27(3):259-66. PubMed ID: 12537979
[TBL] [Abstract][Full Text] [Related]
15. Cytotoxic responses to N-(4-hydroxyphenyl)retinamide in human pancreatic cancer cells.
Messner MC; Cabot MC
Cancer Chemother Pharmacol; 2011 Aug; 68(2):477-87. PubMed ID: 21072519
[TBL] [Abstract][Full Text] [Related]
16. Cytotoxicity and molecular activity of fenretinide and metabolites in T-cell lymphoid malignancy, neuroblastoma, and ovarian cancer cell lines in physiological hypoxia.
Song MM; Makena MR; Hindle A; Koneru B; Nguyen TH; Verlekar DU; Cho H; Maurer BJ; Kang MH; Reynolds CP
Anticancer Drugs; 2019 Feb; 30(2):117-127. PubMed ID: 30272587
[TBL] [Abstract][Full Text] [Related]
17. 4-oxo-fenretinide, a recently identified fenretinide metabolite, induces marked G2-M cell cycle arrest and apoptosis in fenretinide-sensitive and fenretinide-resistant cell lines.
Villani MG; Appierto V; Cavadini E; Bettiga A; Prinetti A; Clagett-Dame M; Curley RW; Formelli F
Cancer Res; 2006 Mar; 66(6):3238-47. PubMed ID: 16540676
[TBL] [Abstract][Full Text] [Related]
18. [The role of reactive oxygen species in N-[4-hydroxyphenyl] retinamide induced apoptosis in bladder cancer cell lineT24].
Liu J; Li AP; Li CP; Zhang ZD; Zhou JW
Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi; 2005 Jun; 23(3):191-4. PubMed ID: 16124896
[TBL] [Abstract][Full Text] [Related]
19. 4-HPR-mediated leukemia cell cytotoxicity is triggered by ceramide-induced mitochondrial oxidative stress and is regulated downstream by Bcl-2.
Morales MC; Pérez-Yarza G; Rementería NN; Boyano MD; Apraiz A; Gómez-Muñoz A; Pérez-Andrés E; Asumendi A
Free Radic Res; 2007 May; 41(5):591-601. PubMed ID: 17454142
[TBL] [Abstract][Full Text] [Related]
20. Reactive oxygen species mediate N-(4-hydroxyphenyl)retinamide-induced cell death in malignant T cells and are inhibited by the HTLV-I oncoprotein Tax.
Darwiche N; Abou-Lteif G; Bazarbachi A
Leukemia; 2007 Feb; 21(2):261-9. PubMed ID: 17122865
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
