BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

131 related articles for article (PubMed ID: 14604658)

  • 1. New analogues of AHMA as potential antitumor agents: synthesis and biological activity.
    Chang JY; Lin CF; Pan WY; Bacherikov V; Chou TC; Chen CH; Dong H; Cheng SY; Tasi TJ; Lin YW; Chen KT; Chen LT; Su TL
    Bioorg Med Chem; 2003 Nov; 11(23):4959-69. PubMed ID: 14604658
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Antitumor AHMA linked to DNA minor groove binding agents: synthesis and biological evaluation.
    Rastogi K; Chang JY; Pan WY; Chen CH; Chou TC; Chen LT; Su TL
    J Med Chem; 2002 Sep; 45(20):4485-93. PubMed ID: 12238927
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Synthesis and structure-activity relationships of potential anticancer agents: alkylcarbamates of 3-(9-acridinylamino)-5-hydroxymethylaniline.
    Su TL; Chen CH; Huang LF; Chen CH; Basu MK; Zhang XG; Chou TC
    J Med Chem; 1999 Nov; 42(23):4741-8. PubMed ID: 10579838
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Synthesis and antitumor activity of 5-(9-acridinylamino)anisidine derivatives.
    Bacherikov VA; Chang JY; Lin YW; Chen CH; Pan WY; Dong H; Lee RZ; Chou TC; Su TL
    Bioorg Med Chem; 2005 Dec; 13(23):6513-20. PubMed ID: 16140018
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Development of DNA topoisomerase II-mediated anticancer agents, 3-(9-acridinylamino)-5-hydroxymethylanilines (AHMAs) and related compounds.
    Su TL
    Curr Med Chem; 2002 Sep; 9(18):1677-88. PubMed ID: 12171550
    [TBL] [Abstract][Full Text] [Related]  

  • 6. 9-substituted acridine derivatives with long half-life and potent antitumor activity: synthesis and structure-activity relationships.
    Su TL; Chou TC; Kim JY; Huang JT; Ciszewska G; Ren WY; Otter GM; Sirotnak FM; Watanabe KA
    J Med Chem; 1995 Aug; 38(17):3226-35. PubMed ID: 7650675
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Structure-activity relationships for substituted bis(acridine-4-carboxamides): a new class of anticancer agents.
    Gamage SA; Spicer JA; Atwell GJ; Finlay GJ; Baguley BC; Denny WA
    J Med Chem; 1999 Jul; 42(13):2383-93. PubMed ID: 10395479
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Potent antitumor 9-anilinoacridines and acridines bearing an alkylating N-mustard residue on the acridine chromophore: synthesis and biological activity.
    Su TL; Lin YW; Chou TC; Zhang X; Bacherikov VA; Chen CH; Liu LF; Tsai TJ
    J Med Chem; 2006 Jun; 49(12):3710-8. PubMed ID: 16759114
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Synthesis and antiproliferative activity of 9-benzylamino-6-chloro-2-methoxy-acridine derivatives as potent DNA-binding ligands and topoisomerase II inhibitors.
    Zhang W; Zhang B; Zhang W; Yang T; Wang N; Gao C; Tan C; Liu H; Jiang Y
    Eur J Med Chem; 2016 Jun; 116():59-70. PubMed ID: 27060757
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Structure-activity relationships for acridine-substituted analogues of the mixed topoisomerase I/II inhibitor N-[2-(dimethylamino)ethyl]acridine-4-carboxamide.
    Spicer JA; Gamage SA; Atwell GJ; Finlay GJ; Baguley BC; Denny WA
    J Med Chem; 1997 Jun; 40(12):1919-29. PubMed ID: 9191970
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Crystallization and preliminary X-ray analysis of anti-cancer agent 3-(9-acridinylamino)-5-(hydroxymethyl)aniline complexed with the DNA hexamer d(CGTACG)2.
    Dong X
    Biochim Biophys Acta; 2003 Jan; 1625(1):27-9. PubMed ID: 12527422
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Influence of polyamine architecture on the transport and topoisomerase II inhibitory properties of polyamine DNA-intercalator conjugates.
    Wang L; Price HL; Juusola J; Kline M; Phanstiel O
    J Med Chem; 2001 Oct; 44(22):3682-91. PubMed ID: 11606133
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Novel tetra-acridine derivatives as dual inhibitors of topoisomerase II and the human proteasome.
    Vispé S; Vandenberghe I; Robin M; Annereau JP; Créancier L; Pique V; Galy JP; Kruczynski A; Barret JM; Bailly C
    Biochem Pharmacol; 2007 Jun; 73(12):1863-72. PubMed ID: 17391647
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Synthesis and antiinflammatory evaluation of 9-anilinoacridine and 9-phenoxyacridine derivatives.
    Chen YL; Lu CM; Chen IL; Tsao LT; Wang JP
    J Med Chem; 2002 Oct; 45(21):4689-94. PubMed ID: 12361395
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Oxiranylmethyloxy or thiiranylmethyloxy-azaxanthones and -acridone analogues as potential topoisomerase I inhibitors.
    Cho HJ; Jung MJ; Kwon Y; Na Y
    Bioorg Med Chem Lett; 2009 Dec; 19(23):6766-9. PubMed ID: 19836231
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Synthesis and antitumor properties of N-[2-(dimethylamino)ethyl]carboxamide derivatives of fused tetracyclic quinolines and quinoxalines: a new class of putative topoisomerase inhibitors.
    Deady LW; Kaye AJ; Finlay GJ; Baguley BC; Denny WA
    J Med Chem; 1997 Jun; 40(13):2040-6. PubMed ID: 9207945
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Rational design, synthesis, and biological evaluation of bis(pyrimido[5,6,1-de]acridines) and bis(pyrazolo[3,4,5-kl]acridine-5-carboxamides) as new anticancer agents.
    Antonini I; Polucci P; Magnano A; Sparapani S; Martelli S
    J Med Chem; 2004 Oct; 47(21):5244-50. PubMed ID: 15456268
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Synthesis and biological evaluation of modified acridines: the effect of N- and O- substituent in the nitrogenated ring on antitumor activity.
    Sánchez I; Reches R; Caignard DH; Renard P; Pujol MD
    Eur J Med Chem; 2006 Mar; 41(3):340-52. PubMed ID: 16413635
    [TBL] [Abstract][Full Text] [Related]  

  • 19. BO-0742, a derivative of AHMA and N-mustard, has selective toxicity to drug sensitive and drug resistant leukemia cells and solid tumors.
    Lee CH; Chou TC; Su TL; Yu J; Shao LE; Yu AL
    Cancer Lett; 2009 Apr; 276(2):204-11. PubMed ID: 19108949
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Synthesis and antiproliferative activity of some variously substituted acridine and azacridine derivatives.
    Ferlin MG; Marzano C; Chiarelotto G; Baccichetti F; Bordin F
    Eur J Med Chem; 2000 Sep; 35(9):827-37. PubMed ID: 11006484
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.